A5081128134- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Emergency and Acute Care Studies
- Health and Conflict Studies
- Global Maternal and Child Health
- Primary Care and Health Outcomes
- Healthcare Systems and Reforms
- Tuberculosis Research and Epidemiology
- Global Health and Surgery
- Healthcare Systems and Practices
- Interprofessional Education and Collaboration
- Parasitic infections in humans and animals
- Health and Medical Studies
Public Health Institute
2007-2009
National Institutes of Health
2009
Tampere University
2008
Helsinki University Hospital
1999
University of Helsinki
1999
The strong herd immunity effect and the serotype replacement associated with use of pneumococcal conjugate vaccine have highlighted importance asymptomatic carriage. To describe development pneumoccoccal carriage in a developing country setting we carried out longitudinal study Bangladesh.Ninety-nine children, born Savar, Bangladesh between May 2000 April 2001, were enrolled their families. Nasopharyngeal samples collected at prescheduled 2-4 week intervals from index children family...
Asymptomatic nasopharyngeal carriage is the main reservoir for transmission of Streptococcus pneumoniae. The rate both and pneumococcal disease decreases with age. To what extent these changes are result developing natural immunity currently a subject debate.To study hypothesis that previous induces serotype-independent protective to new colonization.We compared rates acquisition children different histories. We identified 435 episodes during first year life in follow-up data 99 Bangladeshi...
SUMMARY The burden of pneumococcal carriage is largest in developing countries from which, however, detailed studies on transmission are missing. In this study we followed nasopharyngeal Bangladeshi infants ( n =99) birth, with 2-week sampling intervals until age 4 months, and monthly thereafter 1 year, also their family members at the same intervals. We assessed dependence acquisition rates age, serotype, serotype-specific exposure (i.e. transmission) current state (yes/no). A statistical...
The chessboard modification of the quellung method for serotyping Streptococcus pneumoniae (Pneumococcus) was introduced in Gonoshasthaya Vaccine Research Laboratory, a small laboratory Bangladesh. We applied initial bench-side training and subsequent continuous surveillance quality assurance as approaches good practice. Results obtained this on 1,101 consecutive isolates had satisfactory sensitivity (85.1-100%) specificity (97.9-99.9%) 10 most common serogroups/types pneumococci when...
Among the many challenges facing populations disrupted by complex emergencies, personal security and food rank much higher than access to healthcare. However, over time health needs assume increasing importance. Many crises occur in settings where background incidence of TB is already high; social economic conditions are then highly conducive amplification existing problem. Innovative approaches delivery diagnostic treatment services, transition planning integration with other healthcare...
Background: In Somalia, there has been no functioning national tuberculosis (TB) programme for the past 16 years. As a consequence, until recently TB treatment regimes were non-standardised, making development of drug resistance imminent. No sensitivity testing was available. Our aim to re-establish culture laboratory in Somalia and describe prevalence Mogadishu. Methods: 2006 performing cultures established Sputum samples from clinically suspected patients three clinics Mogadishu area...