A5012107728- Chronic Obstructive Pulmonary Disease (COPD) Research
- High Altitude and Hypoxia
- Heart Rate Variability and Autonomic Control
- Hemoglobinopathies and Related Disorders
- RNA modifications and cancer
- Iron Metabolism and Disorders
- Erythropoietin and Anemia Treatment
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
Genomed (Poland)
2024
Voronezh State Medical Academy named after N.N. Burdenko
2016-2019
Ministry of Health of the Russian Federation
2016
Anemia of chronic disease (ACD) is one the most frequent forms anemia often observed in patients with infections, cancer and inflammatory or autoimmune diseases. The underlying mechanisms are complex include dysregulation iron homeostasis erythropoietin production, impaired proliferation erythroid progenitor cells reduced life span red blood cells. Moreover, ACD superimposed by malnutrition, bleeding renal failure. mediated through cytokines characterized low serum (hypoferremia) increased...
Introduction. Next-generation sequencing (NGS) is a molecular approach that can provide clinicians with comprehensive information about patient’s profile, which an important aspect of the effective application targeted therapy. Aim. To assess frequency tumor somatic mutations in non-small cell lung cancer (NSCLC) cohort Russian patients to subsequently optimize diagnostics and personalize treatment strategies. Materials methods. The study included results NGS testing from 1.400 NSCLC between...
Until recently, compensatory erythrocytosis related to impaired renal blood circulation, treatment with some pharmacological agent, smoking, etc., was considered as one of the obligatory signs advanced chronic obstructive pulmonary disease (COPD). Currently, normochromic normocytic anemia in COPD patients diagnosed according results several studies. Prevalence data on differ significantly from 7.5% 33%. It is unclear, if a systemic feature or comorbidity. This article review about...