A5008176512- Viral Infections and Vectors
- Respiratory viral infections research
- Autophagy in Disease and Therapy
- Influenza Virus Research Studies
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Gut microbiota and health
- Herpesvirus Infections and Treatments
- Animal Virus Infections Studies
- Mangiferin and Mango Extracts
- Food Allergy and Anaphylaxis Research
Wenzhou Medical University
2020-2021
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2020-2021
Children with nonalcoholic fatty liver disease (NAFLD) display an altered gut microbiota compared healthy children. However, little is known about the fecal bile acid profiles and their association dysbiosis in pediatric NAFLD. A total of 68 children were enrolled this study, including 32 NAFLD patients 36 Fecal samples collected analyzed by metagenomic sequencing to determine changes NAFLD, ultra-performance liquid chromatography coupled tandem mass spectrometry (UPLC-MS/MS) system was used...
Abstract This study aimed to investigate the mechanism of mangiferin on regulating endoplasmic reticulum (ER) stress in acute liver injury. The mouse model injury was established by injection LPS/D-GalN. primary hepatocytes were stimulated with LPS induce vitro model. effect miR-20a/101a luciferase activity Nrf2 3′-UTR assessed reporter assay. Mangiferin improved function, inhibited oxidative and ER down-regulated expressions miR-20a miR-101a LPS/D-GalN-induced mice LPS-induced hepatocytes....
In recent years, the incidence of varicella cases is rising, and outbreaks are frequently being reported worldwide. Our study aims to analyze association between serum antibody level in post-vaccine era. We retrieved analyzed prevalence data for children age 1–14 years Wenzhou, China during 2010–2018. A cross-sectional seroepidemiology analysis was carried out a series 168 general healthy as well at outbreak Wenzhou. showed significant surge aged 10–14 2017 2018 while they were kept...
Objective To explore the relationship between influenza-like-illness in children and meteorological factors Wenzhou. Methods The data of were collected from May 2011 to December 2017 Yuying children’s hospital affiliated Wenzhou Medical University. The city same period. relevant regression analysis conducted by SPSS26.0. Results The was bimodal popular spring or summer winter. peak often occurred when monthly mean temperature 10°C 30 °C. incidence negatively correlated with...