A5005989732- Proteins in Food Systems
- Surfactants and Colloidal Systems
- Polymer Surface Interaction Studies
- Lipid Membrane Structure and Behavior
- Skin and Cellular Biology Research
- Dyeing and Modifying Textile Fibers
- Photonic Crystals and Applications
- Force Microscopy Techniques and Applications
- Electrochemical Analysis and Applications
- Spectroscopy and Quantum Chemical Studies
- Microfluidic and Bio-sensing Technologies
- Hair Growth and Disorders
- Nail Diseases and Treatments
- Food Allergy and Anaphylaxis Research
- Advanced Physical and Chemical Molecular Interactions
- Molecular spectroscopy and chirality
- Conducting polymers and applications
- Microencapsulation and Drying Processes
- Hydrogels: synthesis, properties, applications
- Advancements in Transdermal Drug Delivery
- Polysaccharides Composition and Applications
University of Huddersfield
2016
University of Manchester
2012-2014
Unilever (United Kingdom)
2010-2013
University of Leeds
2008-2012
Wilton Park
2008
Monoglycerides and unsaturated fatty acids, naturally present in trace amounts the stratum corneum (top layer of skin) lipid matrix, are commonly used pharmaceutical, cosmetic health care formulations. However, a detailed molecular understanding how oil additives get incorporated into skin lipids from topical application and, once incorporated, they affect properties integrity matrix remains unexplored. Using ceramide 2 bilayers as surrogates, we use series dynamics simulations with six...
Molecular dynamics simulations of non-ionic triphenylene-based chromonic liquid crystal molecules demonstrate self-assembly the into stacks and “quasi-isodesmic” aggregation behaviour.
The influence of the polysaccharide charge distribution on structure, thickness, and reversal interfacial layers, formed by adsorbed positively charged protein oppositely polysaccharide, has been investigated using a lattice-based self-consistent field (SCF) approach. We compare adsorption behaviour uniformly model with that consisting short long block carrying different densities. For homogeneously we observe resulting layer is closer to mixed + film, rather than multi-layer. also find...
The effect on the adsorbed layer properties of modification αS1-casein by covalent bonding with an uncharged polysaccharide side chain has been investigated using lattice-based self-consistent field (SCF) theory. Interactions between two hydrophobic planar surfaces coated a modified have studied as function pH and ionic strength. While interactions unmodified layers become attractive at high strength, it shown that presence attachment to molecule can confer net repulsive over wide range salt...
We model cyclic voltammetry experiments on supported lipid films where a non-trivial dependence of the capacitance applied voltage is observed. Previously, based mean-field treatment Flory–Huggins type, under assumption strongly screened electrostatic interactions, it has been hypothesized that peaks in capacitance-vs.-voltage profiles correspond to sequence structural or phase transitions within adsorbed film. To examine this hypothesis, study we use both calculations and Monte Carlo...
Keratins are important structural proteins found in skin, hair and nails. Keratin Intermediate Filaments major components of corneocytes, nonviable horny cells the Stratum Corneum, outermost layer skin. It is considered that interactions between unstructured domains key factor maintaining elasticity skin.We have developed a model for keratin intermediate filaments based on self-consistent field theory. The represented by charged surfaces, disordered terminal keratins heteropolymers grafted...
We have developed a model for the interactions between keratin intermediate filaments based on self-consistent field theory. The are represented by charged surfaces, and disordered terminal domains of keratins heteropolymers grafted to these surfaces. estimate system is close charge compensation point where heteropolymer grafting density matched surface density. Using protein with amino acid resolution domains, we find that chains can mediate weak attraction origin combination bridging...
We model cyclic voltammetry experiments on supported lipid films where a non-trivial dependence of the capacitance applied voltage is observed. Previously, based mean-field treatment Flory-Huggins type, under assumption strongly screened electrostatic interactions, it has been hypothesized that peaks in capacitance-vs-voltage profiles correspond to sequence structural or phase transitions within interface. To examine this hypothesis, study we use both calculations and Monte Carlo simulations...