Larissa Akeme Nakano

ORCID: 0000-0002-6838-3306
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About
Contact & Profiles
Research Areas
  • Gallbladder and Bile Duct Disorders
  • Pediatric Hepatobiliary Diseases and Treatments
  • Hepatitis B Virus Studies
  • Liver Diseases and Immunity
  • Hepatitis C virus research
  • Liver Disease and Transplantation
  • Drug Transport and Resistance Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Systemic Lupus Erythematosus Research
  • Biliary and Gastrointestinal Fistulas

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2018-2020

Between 50% and 86% of patients with autoimmune hepatitis (AIH) relapse after immunosuppression withdrawal; long-term is associated increased risk neoplasias infections. Chloroquine diphosphate (CQ) an immunomodulatory drug that reduces the flares in rheumatologic diseases. Our aims were to investigate efficacy safety CQ for maintenance biochemical remission AIH a double-blind randomized trial define subgroup obtained greater benefit from its use. A total 61 histologic (90.1% type 1 [AIH-1])...

10.1002/hep4.1275 article EN cc-by-nc-nd Hepatology Communications 2018-11-14

Summary Introduction: Hepatitis B is an important public health problem in the world and one of forms contagion would be through vertical transmission. Precose diagnosis allows adoption prophylaxis measures, which results prevention more than 90% cases. Objective: To describe prevalences transmission compare two generations (mother/patient patient/child). Method: This was a cross-sectional study, included 101 patients. The interviews were performed application instrument data collection...

10.1590/1806-9282.64.02.154 article EN Revista da Associação Médica Brasileira 2018-02-01

Abstract Background Health care costs are growing faster than the rest of global economy, according to World Organization (WHO). Countries’ health expenditures include paying for general medicine, diagnostic procedures, hospitalizations and surgeries, as well medications prescribed treatment. Primary biliary cholangitis (PBC) is a rare autoimmune liver disease first line available treatment ursodeoxycholic acid (UDCA), however, direct indirect expensive. Main aim this trial was assess if...

10.1186/s12876-020-01399-5 article EN cc-by BMC Gastroenterology 2020-08-05
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