Débora Raquel Benedita Terrabuio
A5058826602- Liver Diseases and Immunity
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Hepatitis B Virus Studies
- Organ Transplantation Techniques and Outcomes
- Systemic Lupus Erythematosus Research
- Gallbladder and Bile Duct Disorders
- Hepatitis Viruses Studies and Epidemiology
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Drug Transport and Resistance Mechanisms
- Trace Elements in Health
- SARS-CoV-2 and COVID-19 Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Microscopic Colitis
- Antibiotics Pharmacokinetics and Efficacy
- Parasites and Host Interactions
- Drug-Induced Hepatotoxicity and Protection
- Antibiotic Resistance in Bacteria
- Renal Transplantation Outcomes and Treatments
- Mosquito-borne diseases and control
- Dermatological and COVID-19 studies
- Alkaline Phosphatase Research Studies
- Inflammatory Bowel Disease
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2025
Universidade de São Paulo
2013-2025
Hospital Universitário da Universidade de São Paulo
2024
Hospital São Paulo
2023
Amsterdam University Medical Centers
2023
Vrije Universiteit Amsterdam
2023
Radboud University Nijmegen
2022
Radboud University Medical Center
2022
ERN RARE-LIVER
2022
Saarland University
2022
To assess maternal and fetal outcomes clinical management of pregnancy in patients with autoimmune hepatitis (AIH).There is a paucity information about outcomes, AIH activity during the postpartum period. There no consensus administration azathioprine breastfeeding.Retrospective analysis 54 pregnancies (3 still progress) 39 patients.The median age at conception was 24 years, 68.4% women had liver cirrhosis. Before early pregnancy, prednisone were administered 48.1%, but treatment regimen...
Background & AimsGenetic ancestry or racial differences in health outcomes exist diseases associated with systemic inflammation (eg, COVID-19). This study aimed to investigate the association of genetic and race acute-on-chronic liver failure (ACLF), which is characterized by acute inflammation, multi-organ failure, high risk short-term death.MethodsThis prospective cohort analyzed a comprehensive set data, including among several others, 1274 patients acutely decompensated cirrhosis who...
Abstract Background Patients colonized with carbapenem-resistant Enterobacteriaceae (CRE) are at higher risk of developing CRE infection after liver transplantation (LT), associated high morbidity and mortality. Prediction model for LT among carriers could be useful to target preventive strategies. Methods Multinational multicenter cohort study consecutive adult patients underwent before or LT, from January 2010 December 2017. Risk factors were analyzed by univariate analysis Fine-Gray...
Coronavirus disease 2019 (COVID-19) is a proinflammatory and prothrombotic condition, but its impact on adrenal function has not been adequately evaluated.A 46-year-old woman presented with abdominal pain, hypotension, skin hyperpigmentation after COVID-19 infection. The patient had hyponatremia, serum cortisol <1.0 ug/dL, ACTH of 807 pg/mL aldosterone <3 ng/dL. Computed tomography (CT) findings enlargement no parenchymal minimal peripheral capsular enhancement contrast were consistent...
Direct antiviral agents (DAAs) including sofosbuvir (SOF), daclatasvir (DCV), simeprevir (SIM) and ombitasvir, paritaprevir dasabuvir were introduced 2015 in Brazil for treatment of hepatitis C virus (HCV) infection. The aims this study to assess effectiveness safety HCV with DAA real-life world a highly admixed population from Brazil. All Brazilian reference centers invited take part web-based registry, prospectively conducted by the Society Hepatology, outcomes DAAs. Data be collected...
Abstract Background Wilson disease (WD) is an autosomal recessive disorder that leads to organ toxicity due copper overload. Early diagnosis complicated by the rarity and diversity of manifestations. Objective To describe diagnostic features response treatment in our cohort WD patients. Methods This was a retrospective analysis 262 patients stratified clinical presentation, complementary exams, ATP7B genotyping, treatment. Results Symptoms occurred at average age 17.4 (7–49) years, were...
Abstract Background Autoantibodies to ribosomal P proteins (anti‐rib P) are specific serological markers for systemic lupus erythematosus ( SLE ) and associated with liver involvement in this disease. The similarity autoimmune background between hepatitis AIH ‐associated raises the possibility that anti‐rib antibodies might also have relevance . Aims To evaluate frequency clinical significance of a large cohort. Methods Sera obtained at diagnosis 96 patients 82 healthy controls were tested...
ABSTRACT Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed describe the safety of two doses COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed by additional mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised (IC) adults, compared immunocompetent/healthy (H) individuals. phase 4, multicenter, open label included solid organ transplant and hematopoietic stem cell recipients, cancer patients...
The impact of coronavirus disease-19 (COVID-19) in liver recipients remains largely unknown. Most data derive from small retrospective series patients transplanted years ago. We aimed to report a single-center case five consecutive the early postoperative period deceased-donor transplantation who developed nosocomial COVID-19. Two presented important respiratory discomfort and eventually died. One was 69 old had severe coronary disease. She rapidly worsened after COVID-19 diagnosis on 9th...
Between 50% and 86% of patients with autoimmune hepatitis (AIH) relapse after immunosuppression withdrawal; long-term is associated increased risk neoplasias infections. Chloroquine diphosphate (CQ) an immunomodulatory drug that reduces the flares in rheumatologic diseases. Our aims were to investigate efficacy safety CQ for maintenance biochemical remission AIH a double-blind randomized trial define subgroup obtained greater benefit from its use. A total 61 histologic (90.1% type 1 [AIH-1])...
Aim: Up to 40% of patients with primary biliary cholangitis (PBC) will have a suboptimal biochemical response ursodeoxycholic acid (UDCA), which can be improved by the addition fibrates. This exploratory study aims evaluate long-term real-life different fibrates, including ciprofibrate, in subjects UDCA-unresponsive PBC. Methods: The Brazilian Cholestasis Study Group multicenter database was reviewed assess rates UDCA plus fibrates PBC 1 and 2 years after treatment initiation validated...
Abstract Background Carbapenem‐resistant Enterobacterales (CRE) colonisation at liver transplantation (LT) increases the risk of CRE infection after LT, which impacts on recipients’ survival. Colonization status usually becomes evident only near LT. Thus, predictive models can be useful to guide antibiotic prophylaxis in endemic centres. Aims This study aimed identify factors for LT order build a model. Methods Retrospective multicentre including consecutive adult patients who underwent from...
Abstract Background Cirrhotic patients are highly exposed to healthcare services and antibiotics. Although pre‐liver transplantation (LT) infections directly related the worsening of liver function, impact these on LT outcomes is still unclear. This study aimed identify effect multidrug‐resistant microorganism (MDRO) before survival after LT. Methods Retrospective that included who underwent between 2010 2019. Variables analyzed were patients’ comorbidities, underlying diseases, time waiting...