A5066874751- Advanced Sensor and Energy Harvesting Materials
- Non-Invasive Vital Sign Monitoring
- Electrical and Bioimpedance Tomography
- Wireless Body Area Networks
- Advanced biosensing and bioanalysis techniques
- Wireless Power Transfer Systems
- Microfluidic and Bio-sensing Technologies
- Micro and Nano Robotics
- Advanced Chemical Sensor Technologies
- Graphene research and applications
- Graphene and Nanomaterials Applications
- ECG Monitoring and Analysis
- Electrochemical sensors and biosensors
- Energy Harvesting in Wireless Networks
- Hemodynamic Monitoring and Therapy
- EEG and Brain-Computer Interfaces
- Biosensors and Analytical Detection
- Photoacoustic and Ultrasonic Imaging
- Analytical Chemistry and Sensors
- Neuroscience and Neural Engineering
- 3D Printing in Biomedical Research
- Tactile and Sensory Interactions
- Cleft Lip and Palate Research
- Soft Robotics and Applications
- Ultrasound Imaging and Elastography
Imperial College London
2016-2025
Universidade de São Paulo
2025
Universidade dos Açores
2024
Centro Hospitalar Lisboa Norte
2024
Allegheny General Hospital
2024
In sport, exercise and healthcare settings, there is a need for continuous, non-invasive monitoring of biomarkers to assess human performance, health wellbeing. Here we report the development flexible microfluidic platform with fully integrated sensing on-body testing sweat. The system can simultaneously selectively measure metabolite (e.g. lactate) electrolytes pH, sodium) together temperature internal calibration. construction designed such that continuous flow sweat pass through an array...
Biosensors based on graphene field effect transistors (GFETs) have the potential to enable development of point-of-care diagnostic tools for early stage disease detection. However, issues with reproducibility and manufacturing yields sensors, but also Debye screening unwanted detection nonspecific species, prevented wider clinical use technology. Here, we demonstrate that our wafer-scalable GFETs array platform enables meaningful results. As a case study high relevance, an accurate robust...
Precise manipulation of flexible surgical tools is crucial in minimally invasive procedures, necessitating a miniature and robotic probe that can precisely direct the instruments. In this work, we developed polymer-based fiber with thermal actuation mechanism by local heating along sides single fiber. The robot was fabricated highly scalable drawing technology using common low-cost materials. This low-profile (below 2 millimeters diameter) exhibits remarkable motion precision 50 micrometers)...
Wearable biomedical technology has gained much support lately as devices have become more affordable to the general public and they can easily interact with mobile phones other platforms. The feasibility accuracy of data generated by these so replace standard medical methods in use today is still under scrutiny. In this paper, we present an ear-worn device measure cardiovascular sweat parameters during physical exercise. ECG bipolar recordings capture electric potential around both ears,...
Graphene field-effect transistor (GFET) biosensors exhibit high sensitivity due to a large surface-to-volume ratio and the of Fermi level presence charged biomolecules near surface. For most reported GFET biosensors, bulky external reference electrodes are used which prevent their full-scale chip integration contribute higher costs per test. In this study, arrays with on-chip integrated liquid were employed for COVID-19 detection functionalized either antibody or aptamer selectively bind...
Real-time monitoring of intrabody pressures can benefit from the use miniaturized force sensors during surgical interventions or for recovery period thereafter. Herein, we present a sensor made poly(vinylidene fluoride)-co-trifluoroethylene (P(VDF-TrFE)) with simple fabrication process that has been integrated into tip medical catheter intraluminal pressure monitoring, as well an implantable device power consumption 180 μW obtained by near-field communication (NFC) interface to monitor...
Flexible electronic materials combined with micro-3D fabrication present new opportunities for wearable biosensors and medical devices. This Research Article introduces a novel carbon-nanotube-coated force sensor, successfully combining the advantages of flexible conductive nanomaterials versatility two photon polymerization technologies creating functional 3D microstructures. The device employs microsprings varying configurations geometries real-time sensing. To demonstrate its practical...
In this article, a novel method for measuring the volume of urinary bladder non-invasively is presented that relies on principles dictated by Electrical Impedance Tomography (EIT). The electronic prototype responsible injecting innocuous electrical currents to lower abdominal region and developed voltage levels fully described, as well computational models resolution so-called Forward Inverse Problems in Imaging. simultaneous multi-tone injection current provided high performance Field...
Excessive stress is one of the main causes mental illness. Long-term exposure could affect one's physiological wellbeing (such as hypertension) and psychological condition depression). Multisensory information such heart rate variability (HRV) pH can provide suitable about physical stress. This paper proposes a novel approach for monitoring using disposable flexible sensors. By integrating amplifiers with commercially available polyvinylidene difluoride (PVDF) mechanical deformation sensor...
Flexible endomicroscopes commonly use coherent fiber bundles with high core densities to facilitate high-resolution in vivo imaging during endoscopic and minimally-invasive procedures. However, under-sampling due the inter-core spacing limits spatial resolution, making it difficult resolve smaller cellular features. Here, we report a compact rapid piezoelectric transducer (PZT) based bundle-shifting endomicroscopy system which super-resolution (SR) image is restored from multiple...
Mental illnesses are vast and cause a lot of individual social discomfort, with significant healthcare costs associated in terms diagnosis treatment. They can be triggered by number factors including stress, fatigue or anxiety. The physiological, cardiac autonomic changes assessed, centrally, through brain imaging or, peripherally, other signal recording modalities. With recent advances wearable devices, these parameters now assessed natural living conditions as mood disorders such...
Implantable devices represent the future of remote medical monitoring and administration both chemical physical therapies to patients. Although some these are already in market, security mechanisms deployed inside them withstand deliberate external influence still decades away from robust digital data schemes employed modern distributed networks days. Medical theft, spoofing, disclosure pose serious threats that can ultimately lead individual social stigmas or even death. In this article, we...
Cancer is one of the leading causes high mortality worldwide, affecting most body organs including breast and colon. Triple‐negative (TNBC) colorectal cancers (CRC) usually present poorest clinical outcomes lowest disease‐free survival rates among different cancer types. Novel biomarkers for early detection TNBC CRC have been proposed throughout years, although rate success remains limited. Herein, a dual method cancer‐derived exosomes based on measurement Raman spectra in graphene...
ABSTRACT Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed describe the safety of two doses COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed by additional mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised (IC) adults, compared immunocompetent/healthy (H) individuals. phase 4, multicenter, open label included solid organ transplant and hematopoietic stem cell recipients, cancer patients...
Totally implanted access ports (TIAP) are widely used with oncology patients requiring long term central venous for the delivery of chemotherapeutic agents, infusions, transfusions, blood sample collection and parenteral nutrition. Such devices offer a significant improvement to quality life reduced complication rates, particularly infection, in contrast classical catheters. Nevertheless, infections do occur, biofilm formation bringing difficulties treatment infection-related complications...
Cardiac-related diseases are still the number one cause of death worldwide. Methods and technologies to suppress this problem currently being investigated by integrating electrocardiographic (ECG) monitoring with other sensing modalities in order detect these more accurately due course time. In paper, we propose a battery-less flexible device be worn as chest patch for cardiac hemodynamic parameters through electrical acoustic measurements, combined sweat pH level estimation skin...
Abstract Ultrasounds (US) has been used in the past decades as a non-invasive imaging modality. Although employed extensively clinical applications for soft tissue imaging, acoustic beams can also be sensing and actuation biological implants. In this paper we present unified three dimensional (3D) computational framework to simulate performance response of deeply implanted devices US stimulation composed by double piezoelectric layer with different material composition configurations. The...
Periprosthetic infection is one of the most devastating complications following orthopaedic surgery. Rapid detection an can change treatment pathway and improve outcomes for patient. In here, we propose a miniaturized lactate biosensor developed on flexible substrate integrated small-form bone implant to detect infection. The methods fabrication integration are fully described within this study. system performance was comprehensively electrochemically characterised, including with L-lactate...