Paolo Grossi

ORCID: 0000-0003-2883-5061
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About
Contact & Profiles
Research Areas
  • Legal and Labor Studies
  • Cytomegalovirus and herpesvirus research
  • Renal Transplantation Outcomes and Treatments
  • Hepatitis C virus research
  • Transplantation: Methods and Outcomes
  • Historical and Environmental Studies
  • Classical Studies and Legal History
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Comparative constitutional jurisprudence studies
  • Antibiotic Resistance in Bacteria
  • Hepatitis B Virus Studies
  • HIV/AIDS drug development and treatment
  • COVID-19 Clinical Research Studies
  • Antibiotics Pharmacokinetics and Efficacy
  • Antimicrobial Resistance in Staphylococcus
  • SARS-CoV-2 and COVID-19 Research
  • Infective Endocarditis Diagnosis and Management
  • Legal processes and jurisprudence
  • Comparative International Legal Studies
  • Herpesvirus Infections and Treatments
  • Liver Disease Diagnosis and Treatment
  • Human Rights and Immigration
  • Antifungal resistance and susceptibility
  • Organ Transplantation Techniques and Outcomes
  • HIV/AIDS Research and Interventions

University of Insubria
2016-2025

Istituto Ortopedico Gaetano Pini
2025

Ospedale di Circolo e Fondazione Macchi
2014-2024

Hospital for Tropical Diseases
2024

Aziende Socio Sanitarie Territoriale dei Sette Laghi
2018-2024

International Society for Heart and Lung Transplantation
2020-2024

Associazione Italiana Vulvodinia Onlus
2024

IFC Research (United Kingdom)
2024

University of Florence
1997-2023

Escuela Superior de Guerra
2020-2023

This study analyzed salivary samples of COVID-19 patients and compared the results with their clinical laboratory data.

10.1016/j.jinf.2020.04.005 article EN cc-by-nc-nd Journal of Infection 2020-04-14

Several small studies on patients with COVID-19 and haematological malignancies are available showing a high mortality in this population. The Italian Hematology Alliance aimed to collect data from adult who required hospitalisation for COVID-19.This multicentre, retrospective, cohort study included (aged ≥18 years) diagnosis of WHO-defined malignancy admitted 66 hospitals between Feb 25 May 18, 2020, laboratory-confirmed symptomatic COVID-19. Data cutoff analysis was June 22, 2020. primary...

10.1016/s2352-3026(20)30251-9 article EN other-oa The Lancet Haematology 2020-08-13

The COVID-19 pandemic has rapidly evolved and changed our way of life in an unprecedented manner. emergence impacted transplantation worldwide. impact not been just restricted to issues pertaining donors or recipients, but also health-care resource utilization as the intensity cases certain jurisdictions exceeds available capacity. Here we provide a personal viewpoint representing different from around world order outline current on organ transplantation. Based collective experience, discuss...

10.1111/ajt.15876 article EN cc-by-nc-nd American Journal of Transplantation 2020-03-23

Abstract Background A growing body of observational evidence supports the value ceftazidime-avibactam (CAZ-AVI) in managing infections caused by carbapenem-resistant Enterobacteriaceae. Methods We retrospectively analyzed data on use and outcomes CAZ-AVI therapy for Klebsiella pneumoniae carbapenemase–producing K. (KPC-Kp) strains. Multivariate regression analysis was used to identify variables independently associated with 30-day mortality. Results were adjusted propensity score receipt...

10.1093/cid/ciab176 article EN Clinical Infectious Diseases 2021-02-19

Fourteen heart transplant recipients were monitored for human cytomegalovirus (HCMV) infection based on determination of antigenemia, viremia, and DNAemia (by polymerase chain reaction [PCR]) in peripheral blood polymorphonuclear leukocytes (PMNL). Three patients had symptomatic primary, 10 recurrent (3 asymptomatic), 1 (seronegative) no HCMV infection. Severe clinical symptoms appeared when levels viremia/antigenemia greater than 50 infected PMNL/2 x 10(5) cells examined. Of 200 samples...

10.1093/infdis/164.3.488 article EN The Journal of Infectious Diseases 1991-09-01

Transmission of infection via transplantation allografts including solid organs, eyes, and tissues are uncommon but potentially life-threatening events. Donor-derived infections have been documented following organ, tissue, ocular transplants. Each year, more than 70 000 100 corneas, 2 million human tissue implanted worldwide. Single donors may provide for >100 organ recipients; each allograft carries some, largely unquantifiable, risk disease transmission. Protocols screening or infectious...

10.1093/cid/cis519 article EN Clinical Infectious Diseases 2012-06-05

10.1016/j.ijantimicag.2018.11.001 article EN International Journal of Antimicrobial Agents 2018-11-08

Advances in surgical technique, immunosuppression and antimicrobial prophylaxis have resulted significantly reduced morbidity mortality following organ transplantation. As a result, transplantation is currently considered the definitive therapy for individuals with end-organ failure. Despite these advances, unexpected transmission of infections from donor to recipient remains rare complication transplantation; when it does occur, event frequently associated significant (1,2).

10.1111/ajt.12095 article EN cc-by-nc-nd American Journal of Transplantation 2013-03-01

<h2>Summary</h2><h3>Background</h3> Bacterial brain abscesses remain a serious central nervous system problem despite advances in neurosurgical, neuroimaging, and microbiological techniques the availability of new antibiotics. The successful treatment requires surgery, appropriate antibiotic therapy, eradication primary source; nevertheless many controversial issues on management this infection unresolved. <h3>Controversial issues</h3> aim GISIG (Gruppo Italiano di Studio sulle Infezioni...

10.1016/j.ijid.2010.05.010 article EN publisher-specific-oa International Journal of Infectious Diseases 2010-09-17

Donor-derived infections due to multidrug-resistant bacteria are a growing problem in solid organ transplantation, and optimal management options not clear. In 2-year period, 30/214 (14%) recipients received an from 18/170 (10.5%) deceased donors with infection or colonization caused by carbapenem-resistant gram-negative that was unknown at the time of transplantation. Among them, 14/30 (47%) transplant donor bacteremia infection/colonization transplanted were considered high risk...

10.1111/ajt.13317 article EN cc-by-nc-nd American Journal of Transplantation 2015-05-15
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