A5004021884- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Cyclopropane Reaction Mechanisms
- Sulfur-Based Synthesis Techniques
- Radical Photochemical Reactions
- Ginseng Biological Effects and Applications
- Ubiquitin and proteasome pathways
- Probiotics and Fermented Foods
- Endoplasmic Reticulum Stress and Disease
- Autophagy in Disease and Therapy
- Heat shock proteins research
- Chemical Synthesis and Reactions
- Protein Degradation and Inhibitors
- DNA and Nucleic Acid Chemistry
- Gut microbiota and health
- Ferrocene Chemistry and Applications
- Synthesis of Indole Derivatives
- Protein Structure and Dynamics
- Metal complexes synthesis and properties
Chengdu University of Traditional Chinese Medicine
2022-2024
A series of dihydroquinolinones have been synthesized via synergistic catalysis combining photolysis and Lewis base utilizing in situ generated ketenes ortho -amino MBH carbonates.
A metal-free, scalable, and cascade protocol for assembling diverse polysubstituted pyridines from tertiary enaminones α,β-unsaturated sulfonylketimines by cleaving C–N/N–S bonds is reported.
Substituent-controlled regiodivergent synthesis of aza-analogs β-lactam and γ-fused lactam derivatives via the visible-light-induced Wolff rearrangement α-diazoketones azo esters.
Photogenerated ketenes simplify and accelerate the synthesis of diverse cyclic architectures demonstrate their promising applications in flow chemistry.
Developing efficient strategies for synthesizing novel diazocine compounds is valuable because their use has been limited by synthetic accessibility. This work describes the catalytic (4+3) cycloaddition reaction of carbonyl ylides with azoalkenes generated in situ. The rhodium-catalyzed cascade features good atom and step economy, providing first access to oxo-bridged diazocines. product could be synthesized on a gram scale converted into diversely substituted dihydroisobenzofurans.
An efficient, scalable cascade [1,5] hydride transfer/cyclization approach for the construction of spirocyclic pyrazolone-pyrrolo[4,3,2- de ]quinoline skeletons through C(sp 3 )–H functionalization.