A5026811041- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- Phytochemicals and Antioxidant Activities
- Antioxidant Activity and Oxidative Stress
- Microbial Metabolites in Food Biotechnology
- Enzyme Production and Characterization
- Concrete and Cement Materials Research
- Dialysis and Renal Disease Management
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Sarcoidosis and Beryllium Toxicity Research
- Atherosclerosis and Cardiovascular Diseases
- Systemic Lupus Erythematosus Research
- Polyamine Metabolism and Applications
- Phytase and its Applications
- Chemical synthesis and alkaloids
- Fungal Biology and Applications
- 3D Printing in Biomedical Research
- Bioactive Compounds and Antitumor Agents
- Advanced Chemical Sensor Technologies
- Parathyroid Disorders and Treatments
- Magnesium Oxide Properties and Applications
- Chronic Kidney Disease and Diabetes
- Planarian Biology and Electrostimulation
- Innovative concrete reinforcement materials
- Cholesterol and Lipid Metabolism
Jiangnan University
2019-2025
Southern Medical University
2022-2025
Nanfang Hospital
2022-2025
State Key Laboratory of Food Science and Technology
2019-2024
Abstract BACKGROUND Stevia has been proposed as a potential antidiabetic sweetener, mainly based on inconsistent results from stevioside or the plant extract, yet lacking relative experimental evidence individual steviol glycosides (SGs) and their metabolites. RESULTS The systematically revealed that typical SGs final metabolite (steviol) presented an effect streptozotocin (STZ) diabetic mice in all assayed aspects. In general, performance strength of samples followed sequence > glucosyl...
Edible mushroom Antrodia cinnamomea is distinctive for its use in many health supplement products relieving of diverse health-related conditions. A. known rich array bioactive secondary metabolites, predominantly terpenoids, that possess anti-inflammatory properties. Despite the abundance these compounds, only some compounds have demonstrated notable activity. Moreover, there a lack established quality control methods specifically tailored to active constituents products. Consequently, great...
Antrodia cinnamomea is widely known for its bioactive properties, particularly in anti-cancer, anti-inflammatory, and antibacterial areas. Despite the full use of compounds from fruiting body, high-value residues remain largely underexploited. This study presents a novel one-pot gel formation method, utilizing cellulose-riched to create hydrogels as an effective wound-healing dressing. The derived these show desirable including non-drying characteristics, activity against Staphylococcus...
Although enormous efforts have been made to prepare tasty and soluble steviol glycosides (SGs), the structure–property relationship of SGs still remains unclear, neither in experiment fact nor mechanism, such as influence linkage type position substituted glucosyl on physiochemical properties sensory features SGs. The favorable SGs, rebaudioside D (RD) A (RA), possess good edulcorant quality, poor solubility, other significantly different physical properties. This research chose two pairs...
In this study, a monoglucosyl rebaudioside A product was isolated from the mixture of glucosylated obtained most reported and industrial used cyclodextrin glycosyl transferase, Toruzyme 3.0 L (CGTase, L). The molecular structure characterized using LC-MS/MS methylation analysis combined with 1D 2D NMR, indicating that it is 13-[(2-O-(3-α-O-D-glucopyranosyl)-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester (also known as...
Polyphenols from stevia leaves (PPSs) are abundant byproducts steviol glycoside production, which have been often studied as raw extracts for their bioactivities. Herein, the PPSs rich in isochlorogenic acids were antimicrobial and anti-inflammatory properties, well inhibitory effects on digestive enzymes. The presented stronger antibacterial activity against E. coli, S. aureus, P. aeruginosa, B. subtilis than antifungal M. furfur A. niger. Meanwhile, inhibited four cancer cells by more 60%...
Stevia leaves have been claimed to possess the highest antioxidant capacity among botanic foods, yet activity has attributed polyphenols from (PPS). However, most studies about PPS were based on extracts that contain abundant and flavonoids. The excluded flavonoids found similar of epigallocatechin gallate, demonstrating stronger hydrophilic stability than ascorbic acid (VC), vitamin E, or chlorogenic under assayed circumstances. Both their are very stable in various physical environments,...
Abstract Background Endothelial cell (EC) dysfunction leading to microvascular alterations is a hallmark of technique failure in peritoneal dialysis (PD). However, the mechanisms underlying EC PD are poorly defined. Methods We combined RNA sequencing with metabolite set analysis characterize metabolic profile ECs from mouse model PD. This was EC‐selective blockade glycolysis by genetic or pharmacological inhibition 6‐phosphofructo‐2‐kinase/fructose‐2,6‐biphosphatase 3 (PFKFB3) vivo and...
Aims: Effective and applicable predictors of end-stage kidney disease (ESKD) are needed for patients with myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis (MPO-AAV) involvement. We investigated whether urinary matrix metalloproteinase-7 (uMMP7) was associated injury severity incident ESKD in MPO-AAV. Results: A prospective two-stage study conducted 150 newly diagnosed MPO-AAV two independent cohorts. uMMP7 measured on the days initial repeat biopsies. In stage I, a...
In general, polymers that enhance the mechanical strength of gypsum plaster simultaneously decrease its water absorption capability. this research, starting from polyvinyl acetate (PVAc) and alcohol (PVA), respectively, two groups PVA-derived were, partially hydrolyzed acetates (PHPVAs) sulfates (PVAS). The modulation with PHPVA PVAS was studied. Their structure–property relationship investigated. Except for morphology, influence product structure on properties hardened studied, including...
Understanding the edulcorant profile of synthetic glucosyl steviol glycosides (GSGs) and rare natural (SGs) is challenging due to their numerous species rareness. This study developed a computational model based on interactions SG molecules with human sweet bitter taste receptors (hSTR/hBTR). The models demonstrated high correlation between cumulative interaction energies perceived sweetness SGs (R2 = 0.97), elucidating mechanism diverse SGs. It also revealed that more (within three) glucose...