A5006512526- Retinopathy of Prematurity Studies
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Ophthalmology and Visual Health Research
- Retinal Imaging and Analysis
- Neonatal Respiratory Health Research
- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Health Systems, Economic Evaluations, Quality of Life
- Tryptophan and brain disorders
- Ocular Oncology and Treatments
- Photoreceptor and optogenetics research
- Neonatal and fetal brain pathology
- Alzheimer's disease research and treatments
- Ocular Diseases and Behçet’s Syndrome
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical Economics and Policy
- Vascular Malformations and Hemangiomas
- Neuroinflammation and Neurodegeneration Mechanisms
- Restraint-Related Deaths
- Ophthalmology and Eye Disorders
- Telemedicine and Telehealth Implementation
- Dental Education, Practice, Research
- Medical and Biological Sciences
Thomas Jefferson University
2021-2025
Wills Eye Hospital
2021-2025
HealthPartners
2025
American Academy of Ophthalmology
2023
Harvard University
2017-2021
Boston Children's Hospital
2014-2021
Massachusetts Eye and Ear Infirmary
2019-2021
Alcon (France)
2021
Purpose: Because preterm birth and retinopathy of prematurity (ROP) are associated with poor visual acuity (VA) altered foveal development, we evaluated relationships among the central retinal photoreceptors, postreceptor neurons, overlying fovea, VA in ROP. Methods: We obtained optical coherence tomograms (OCTs) born subjects no history ROP (none; n = 61), that resolved spontaneously without treatment (mild; 51), required by laser ablation avascular peripheral retina (severe; 22), as well...
Introduction Intranasal (IN) deferoxamine (DFO) has emerged over the past decade as a promising therapeutic in preclinical experiments across neurodegenerative and neurovascular diseases. As an antioxidant iron chelator, its mechanisms are multimodal, involving binding of brain consequent engagement several pathways to counter pathogenesis multiple We other research groups have shown that IN DFO rescues cognitive impairment rodent models Alzheimer Disease (AD). Methods This study was...
Virtual visits (VVs) are necessitated due to the public health crisis and social distancing mandates COVID-19. However, these have been rare in ophthalmology. Over 3.5 years of conducting >350 ophthalmological VVs, our group has gained numerous insights into best practices. This communication shares experiences with medical community support patient care during this difficult time beyond. We highlight that mastering technological platform choice, optimizing lighting, camera positioning, "eye...
To identify geographic and socioeconomic variables predictive of residential proximity to retinopathy prematurity (ROP) clinical trial locations.This cross-sectional epidemiological study used census tract-level data from three national public sets trial-level ClinicalTrials.gov. Socioeconomic predictors driving distance time the nearest ROP location were identified. Primary outcomes >60 minutes miles traveled site.Multivariate analysis showed that residents more likely travel site if they...
Purpose: Retinopathy of prematurity (ROP) is the leading cause visual impairment in premature infants, and middle-income nations are currently experiencing “third epidemic” ROP. Screening programs essential to prevent negative outcomes, but screening efforts require a great amount resources from healthcare systems difficult marshal, particularly geographically isolated or resource-limited settings. Telemedical using remote digital fundus imaging (RDFI) hold promise alleviating many burdens...
Abstract Purpose: Our study describes the racial/ethnic composition and broad health status/severity of disease cohorts Diabetic Retinopathy Clinical Research (DRCR) clinical trials compares rates non-completion trial to first data report (lost follow up (LTFU)). Methods: This is a retrospective cohort participants in Retina Network that met our inclusion criteria. The primary outcome was lost their associated risk factors. Results: Eight with 3492 Participants who were LTFU more likely...