Lena Altrogge

ORCID: 0000-0002-6871-235X
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About
Contact & Profiles
Research Areas
  • Genetic Mapping and Diversity in Plants and Animals
  • Genetics and Plant Breeding
  • Chromosomal and Genetic Variations
  • Genomics and Phylogenetic Studies
  • Genetic and phenotypic traits in livestock
  • Algal biology and biofuel production
  • Lipid metabolism and biosynthesis
  • Photosynthetic Processes and Mechanisms
  • RNA and protein synthesis mechanisms
  • Plant Molecular Biology Research
  • Genomics and Chromatin Dynamics

University of Bonn
2016-2021

Sequence-indexed insertional libraries in maize (Zea mays) are fundamental resources for functional genetics studies. Here, we constructed a Mutator (Mu) library the B73 inbred background designated BonnMu. A total of 1,152 Mu-tagged F2-families were sequenced using Mu-seq approach. We detected 225,936 genomic Mu insertion sites and 41,086 high quality germinal insertions covering 16,392 annotated genes (37% B73v4 genome). On average, each F2-family BonnMu captured 37 Filtered Gene Set...

10.1104/pp.20.00478 article EN cc-by PLANT PHYSIOLOGY 2020-08-07

Heterosis is the superior performance of F1 hybrids compared with their homozygous, genetically distinct parents. In this study, we monitored transcriptomic divergence maize (Zea mays) inbred lines B73 and Mo17 reciprocal hybrid progeny in primary roots under control water deficit conditions simulated by polyethylene glycol treatment. Single-parent expression (SPE) genes an extreme instance gene complementation, which are active only one two parents but expressed both hybrids. 1,997 2,024...

10.1104/pp.16.01045 article EN PLANT PHYSIOLOGY 2016-12-20

Algae have evolved several mechanisms to adjust changing environmental conditions. To separate from their surroundings, algal cell membranes form a hydrophobic barrier that is critical for life. Thus, it important maintain or the physical and biochemical properties of which are exposed factors. Especially glycerolipids thylakoid membranes, site photosynthesis photoprotection within chloroplasts, affected by different light Since little known about membrane lipid remodeling upon treatments,...

10.1042/bcj20200160 article EN cc-by Biochemical Journal 2020-06-18

Insertional mutagenesis allows for the creation of loss-of-function mutations on a genome-wide scale. In theory, every gene can be 'knocked out' via insertion an additional DNA sequence. Resources sequence-indexed mutants plant and animal model organisms are instrumental functional genomics studies. Such repositories significantly speed up acquisition interesting genotypes allow validation hypotheses regarding phenotypic consequences in reverse genetics. To create such resources,...

10.1093/bioinformatics/btab679 article EN cc-by Bioinformatics 2021-09-23
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