Xiubao Chen

ORCID: 0000-0002-6912-1834
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About
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Research Areas
  • Aquatic Invertebrate Ecology and Behavior
  • Fish Ecology and Management Studies
  • Environmental Toxicology and Ecotoxicology
  • Isotope Analysis in Ecology
  • Fish Biology and Ecology Studies
  • Marine and fisheries research
  • Identification and Quantification in Food
  • Heavy metals in environment
  • Morphological variations and asymmetry
  • Ichthyology and Marine Biology
  • Marine Bivalve and Aquaculture Studies
  • Ferroptosis and cancer prognosis
  • Mercury impact and mitigation studies
  • Orthopaedic implants and arthroplasty
  • Receptor Mechanisms and Signaling
  • Cancer Immunotherapy and Biomarkers
  • RNA modifications and cancer
  • Advanced Chemical Sensor Technologies
  • Cancer, Stress, Anesthesia, and Immune Response
  • Immunotherapy and Immune Responses
  • Marine animal studies overview
  • Mine drainage and remediation techniques
  • Calcium Carbonate Crystallization and Inhibition
  • Cancer-related molecular mechanisms research
  • Fish biology, ecology, and behavior

Chinese Academy of Fishery Sciences
2016-2025

Nanjing Agricultural University
2012-2024

Shandong University of Traditional Chinese Medicine
2022-2023

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2022-2023

Ministry of Agriculture and Rural Affairs
2022-2023

This study aims at investigating the potential targets and functional mechanisms of Scutellariae Radix-Coptidis Rhizoma (QLYD) against atherosclerosis (AS) through network pharmacology, molecular docking, bioinformatic analysis experimental validation.The compositions QLYD were collected from Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform (TCMSP) literature, where main active components corresponding identified. The therapeutic AS excavated using OMIM database,...

10.1016/j.biopha.2023.115210 article EN Biomedicine & Pharmacotherapy 2023-07-25

X-ray electron probe microanalyzer technology was used to study the microchemistry and habitat history of Coilia nasus collected from Dawanzhou section Yangtze River between May June 2023. The Sr/Ca ratio otolith core diameter low (640–1100 µm), representing first stage development. In second stage, C. exhibited two distinct types. type, which included individuals 5HK05 6HK03, exclusively inhabited brackish estuarine waters. comprising 13 individuals, resided in higher-salinity seawater...

10.3390/fishes10030113 article EN cc-by Fishes 2025-03-05

The estuarine tapertail anchovy, Coilia nasus, is a migratory fish with high economic value in China. We collected from the Changjiang River (the Yangtze River) estuary, Qiantang and southern Yellow Sea, studied their relationships using otolith elemental stable isotopic microchemistry signatures to assess population connectivity of C. nasus. Results show that, addition Ca, other elements were present core. δ18O, Na/Ca, Fe/Ca, Cu/Ca values significantly higher than those others, whereas its...

10.3390/fishes7040147 article EN cc-by Fishes 2022-06-23

The authentication of high-quality fishery products originating from specific geographical regions is urgently needed worldwide. Chinese mitten crabs (Eriocheir sinensis), Yangcheng Lake, are prime counterfeiting targets for the same reasons. Foreign that cultured briefly in lake, known as “bathed” crabs, illegally marketed natives, negatively impacting product quality. To establish a method distinguishing and genuine this paper we conduct comparative investigation by an Agilent 7500ce...

10.3390/fishes7010011 article EN cc-by Fishes 2022-01-07

Abstract The gene encoding beta2-adrenergic receptor (β2-AR), adrenoceptor beta 2 ( ADRB2 ), has been reported to closely associated with various cancers. However, its role in lung adenocarcinoma (LUAD) remains controversial. This research shed light on the prognostic value of LUAD and further explored association immune cell infiltration. was significantly decreased LUAD. expression correlated gender, smoking status, T classification, pathologic stage. Patients low group presented poorer...

10.1038/s41598-022-19991-y article EN cc-by Scientific Reports 2022-09-26

Copper (Cu) contamination has become a severe problem in freshwater environments worldwide. The mussel Anodonta woodiana is used as unique bioindicator to monitor Cu environments. However, toxicity and response mechanisms A. are still largely unknown. A sublethal acute exposure experiment (2.0 mg/L for 72 h) was conducted investigate the effects of bioaccumulation on ionoregulatory homeostasis, histological features, transcriptome responses using gills indicator tissue. gill capacity up 474....

10.3390/fishes8070368 article EN cc-by Fishes 2023-07-14

Loss of valued diadromous fishes and their habitats is one the most critical problems in aquatic habitat connection resource management worldwide. In China, Poyang, Dongting, Gaobao, Gucheng, Dongping, Taihu lakes were known to be historical migratory spawning sites anadromous estuarine tapertail anchovy Coilia nasus. However, except for Poyang Lake, it believed that these are no longer used by fish owing overfishing, water pollution, loss connectivity. To confirm this assumption, we an...

10.1016/j.heliyon.2020.e04571 article EN cc-by-nc-nd Heliyon 2020-08-01

Freshwater mussels of Anodonta woodiana were artificially cultured from newly transformed juveniles (day 0) to the onset adulthood 750). Morphological and organogenic development, growth rates, biometric relationships studied during sequential developmental stages. The most obvious feature day 0 was a mobile foot. Adult morphology apparent after 60 days, inner organs well formed. Annuli deposited on shell's surface in winter. Males females became sexually mature at approximately 750 days....

10.1080/07924259.2015.1047039 article EN Invertebrate Reproduction & Development 2015-06-01

To confirm whether Chinese mitten crabs (Eriocheir sinensis), commonly known as hairy or river crabs, in non-Yangcheng Lake areas undergo morphological convergence with the original Yangcheng purse seine and high-standard modified aquaculture ponds after being “introduced” “bathed”-cultured, we employed a geometric morphometrics approach. This approach allowed us to compare analyze dynamic changes carapace morphology of both Kunshan City at 0, 7, 14, 30 days “bathing” culture. The analysis...

10.3390/fishes9010006 article EN cc-by Fishes 2023-12-21

Abstract Background Restocking by introducing hatchery-reared fish into wild habitats aids in the restoration of fishery aquatic ecosystems and reefs to increase abundance resources, restore ecological balance water bodies, enhance ecosystem functioning. Accurately, rapidly, effectively evaluating success restocking using chemical markers (e.g., strontium [Sr]) remains challenging for fisheries management. Consequently, non-lethal sampling, hard tissues, such as fin rays, have received...

10.1186/s13717-024-00501-z article EN cc-by Ecological Processes 2024-02-29

Fanconi anemia (FA) group D2 ( FANCD2 ) is a ferroptosis-related gene crucial for DNA damage repair and negative ferroptosis regulation. Our study aimed to evaluate its prognostic value as well association with immune infiltration in lung adenocarcinoma (LUAD). Transcriptome sequencing data, clinical information, immunohistochemistry data were collected from the TCGA, GEO, HPA databases, respectively, three independent cohorts. Univariate multivariate analyses used assess correlations...

10.3389/fgene.2022.825685 article EN cc-by Frontiers in Genetics 2022-05-11
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