A5084748999- Porphyrin and Phthalocyanine Chemistry
- Photodynamic Therapy Research Studies
- Metal-Catalyzed Oxygenation Mechanisms
- Photochemistry and Electron Transfer Studies
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Photochromic and Fluorescence Chemistry
- Electrochemical Analysis and Applications
- Magnetism in coordination complexes
- Luminescence and Fluorescent Materials
- Conducting polymers and applications
- Nanoplatforms for cancer theranostics
- Oxidative Organic Chemistry Reactions
- Organic Chemistry Cycloaddition Reactions
- Electrochemical sensors and biosensors
- Perovskite Materials and Applications
- Nanomaterials for catalytic reactions
- Organic Electronics and Photovoltaics
- Synthesis and Reactions of Organic Compounds
- Hydrogen embrittlement and corrosion behaviors in metals
- Inorganic and Organometallic Chemistry
- Asymmetric Hydrogenation and Catalysis
- Organic Light-Emitting Diodes Research
- Analytical Chemistry and Sensors
- TiO2 Photocatalysis and Solar Cells
Istanbul Technical University
2013-2025
Polish Academy of Sciences
2012-2013
Istanbul University
2003-2011
In this study, the in vitro photodynamic therapy (PDT) activity of two zinc phthalocyanines (ZnPc1 and ZnPc2) was systematically examined human umbilical vein endothelial cells, focusing on PDT-induced cytotoxicity, reactive oxygen species (ROS) generation, inhibition angiogenic processes. Both ZnPcs demonstrated minimal cytotoxicity absence light, confirming their safety as photosensitizers. ZnPc-PDT led to significant cell death via apoptosis. ZnPc1 exhibited enhanced ROS particularly at...
In this study, the PDT activities of two cationic zinc phthalocyanines, ZnPcs, were investigated in 2D monolayer cultures and 3D spheroids three human cancer cell lines: A253, HT29, FaDu. The results indicate that both molecules are non-toxic absence light, which is a crucial feature an effective photosensitizer. Upon exposure to ZnPc1 exhibited significant cytotoxicity all lines, particularly FaDu cells, spheroids, whereas ZnPc2 showed moderate efficacy compared ZnPc1. using phthalocyanines...
The synthesis of novel tetra-substituted manganese and indium phthalocyanines was achieved by cyclotetramerization corresponding phthalonitrile derivative. new compounds have been characterized using UV-vis, IR, 1H NMR mass spectroscopic data. Spectroelectrochemical characterization an phthalocyanine complex performed for the first time in this paper its electrochemical spectroelectrochemical responses were compared with phthalocyanine, bearing a redox active metal center. Electrochemical...
Abstract This study describes the electrochemical, in situ spectroelectrochemical, electrocolorimetric and electrocatalytic characterization of metallophthalocyanines bearing four dioctylaminocarbonyl biphenyloxy groups (MPc's). While CoPc gives both metal‐based ring‐based redox processes, ZnPc CuPc show only reduction oxidation processes. In‐situ method was applied to investigate color electrogenerated anionic cationic forms complexes. Perchloric acid titrations monitored by cyclic...
A convenient, general procedure for formylation of diverse range phenols with the Duff protocol has been developed. The gives dialdehydes when possible.
The synthesis, spectroscopic and electrochemical properties of new phthalocyanines bearing four morpholine chloro units is reported. Two-step synthesis involved efficient nucleophilic substitution 4,5-dichlorophthalonitrile as the key step. free-base phthalocyanine its several complexes have been characterized using UV-vis, IR, 1 H NMR , 13 C mass data. Voltammetric spectroelectrochemical studies show that while cobalt gives both metal- ring-based, diffusion-controlled, multi-electron...
Two novel phthalonitrile derivatives, bearing two hexyloxy groups and a benzodioxin (or naphthodioxin) annulated ring, along with their corresponding metal-free phthalocyanines (H2Pc) were prepared. FT-IR, mass, electronic absorption, 1H NMR, 13C NMR spectroscopy employed for the characterization of all compounds. The effect hexadeca substituents on photophysical properties Pcs was investigated. Photophysical H2Pc studied in tetrahydrofuran (THF). Fluorescent quantum yields (Pcs) calculated...
The novel tetracationic metallophthalocyanines having diethylmethyl aminoethylsulfanyl groups on the periphery have been synthesized and characterized. compounds tend to form aggregates in aqueous solutions. aggregation of ZnPc 4+ or CoPc , but not that CuPc was hindered by addition surfactants (Triton X-100 Tween 20). Using absorption fluorescence spectroscopic techniques, DNA BSA binding properties presence were also investigated.
Inhibition of stainless steel corrosion in a 3.0 M NaCl solution by 4-(2-diethylamino-ethylsulfanyl)-phthalonitrile (DAESPN) and 4,5-bis(hexylsulfonyl)-phthalonitrile (Bis-HSPN) was investigated polarization electrochemical impedance spectroscopy (EIS) measurements. The values cathodic ( β c ) anodic Tafel slopes, , rate (CR), inhibition efficiences (IE%) obtained from curves resistance (), double-layer capacitance specific () were EIS. Double-layer differences the presence absence...