A5013555424- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Antimicrobial Peptides and Activities
- Bacteriophages and microbial interactions
- Cardiac electrophysiology and arrhythmias
- Bacterial Identification and Susceptibility Testing
- Cardiac Ischemia and Reperfusion
- Heart Failure Treatment and Management
- Biochemical and Structural Characterization
University of Patras
2021-2024
The purpose of the present study was to investigate anti-staphylococcal activity liposomal daptomycin against four biofilm-producing S. aureus and epidermidis clinical strains, three which are methicillin-resistant. Neutral negatively charged daptomycin-loaded liposomes were prepared using methods, namely, thin-film hydration (TFH), a dehydration–rehydration vesicle (DRV) method, microfluidic mixing (MM); moreover, they characterized for drug encapsulation (EE%), size distribution,...
The purpose of the present study was to investigate anti-staphylococcal activity daptomycin and bacteriophage K, alone or in combination, against biofilm-producers non-producers S. aureus epidermidis strains, under biofilm forming cells’ proliferation conditions. Daptomycin K (ATCC 19685B1), different concentrations, were tested 10 Staphylococcus epidermidis, characterized by phenotypes genotypes. quantitative microtiter plate (crystal violet, CV), methylthiazoltetrazolium (MTT), growth...
The purpose of the present study was to investigate anti-staphylococcal activity liposomal daptomycin, against four biofilm-producing S. aureus and epidermidis clinical strains, three which are methicillin resistant. Neutral negatively charged Daptomycin-loaded liposomes were prepared by methods thin film hydration (TFH), DRV microfluidic mixing (MM), characterized for drug encapsulation (EE%), size distribution, zeta-potential, vesicle stability, release integrity. Interestingly, whilst...
(1) Background: The present study aims to investigate the effect of administration Levosimendan and Exenatide in various concentrations, as well coadministration those agents an ischemia-reperfusion injury isolated heart model. (2) Methods: After 30 min perfusion, hearts underwent a period regional ischemia followed by 120 reperfusion. All animals were randomly divided into 12 experimental groups nine each group: Control, Sham, (3) Digox (Negative control, Digoxin 1.67 μg/min), (4) Levo 1...
Introduction. Dalbavancin was approved in Europe 2015 for skin and soft tissue infections. Hypothesis/Gap Statement. Data on methicillin-resistant coagulase-negative staphylococci (MR-CNS) dalbavancin susceptibility are scarce. Aim. To assess the of MR-CNS to other anti-staphylococcal agents. Methodology. A total 443 clinical isolates from patients hospitalized a Greek university hospital during 2.5-year period (January 2018 June 2020) were included. The MICs vancomycin, teicoplanin,...