Т. А. Руженцова

ORCID: 0000-0002-6945-2019
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Respiratory viral infections research
  • Pediatric health and respiratory diseases
  • SARS-CoV-2 and COVID-19 Research
  • Human Health and Disease
  • Viral gastroenteritis research and epidemiology
  • Dermatological and COVID-19 studies
  • COVID-19 Impact on Reproduction
  • Healthcare Systems and Public Health
  • Streptococcal Infections and Treatments
  • Medical and Agricultural Research Studies
  • Child and Adolescent Health
  • Dermatology and Skin Diseases
  • Infectious Encephalopathies and Encephalitis
  • Parvovirus B19 Infection Studies
  • Digestive system and related health
  • Cardiovascular Disease and Adiposity
  • Infant Nutrition and Health
  • Vitamin C and Antioxidants Research
  • Cardiovascular Effects of Exercise
  • Respiratory and Cough-Related Research
  • Autoimmune and Inflammatory Disorders
  • Infant Health and Development
  • Food Allergy and Anaphylaxis Research

Gabrichevsky Institute of Epidemiology and Microbiology
2021-2024

Samara Medical Institute Reaviz
2023-2024

Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2021-2024

Academy of Sciences Republic of Uzbekistan
2024

Central Research Institute of Epidemiology
2012-2021

The article provides an overview of the latest concepts regarding role specific exposomal factors in atopic dermatitis children and adults. As is known, include: air pollutants (external, internal); humidity; metals; water hardness; detergents; pollen other allergens; diet; human lifestyle factors. In this work, main attention paid to all above factors, except for allergy etiopathogenesis (a separate publication will be devoted issue). Based on data systematic reviews, meta-analyses recent...

10.36691/rja16984 article EN Russian Journal of Allergy 2025-02-11

Background: Favipiravir is an antiviral drug, inhibitor of RNA dependent polymerase that preliminarily effective against SARS-CoV-2 virus. The aim this study was to evaluate the efficacy and safety favipiravir for treatment mild moderate coronavirus disease (COVID-19).Methods: We conducted open-labeled, randomized, active-controlled multicenter trial oral dosage form in out- hospitalized patients with COVID-19. organized 10 clinical centers Russia. Eligible had laboratory confirmed by PCR...

10.2139/ssrn.3696907 article EN SSRN Electronic Journal 2020-01-01

The increasing prevalence of atopic dermatitis (AD) over recent decades suggests that environmental factors play an important role in the etiology and pathogenesis disease. Nonspecific refer to external (or exposomal) include human natural influence health a population: for example, socioeconomic status patient; climate, including air temperature, exposure ultraviolet radiation, pollution; living city or rural area. Although studies have shown these on course AD, general, none them...

10.53529/2500-1175-2024-1-5-11 article EN cc-by-sa Allergology and Immunology in Pediatrics 2024-05-05

Objective of the work was to investigate peculiarities gastrointestinal tract disorders in children with coronavirus disease caused by SARS-CoV-2 virus. Materials and methods . We have analyzed frequency, terms emergence, duration character on basis medical records 36 receiving treatment for community-acquired pneumonia etiology (positive virus) children’s infectious department Moscow State Clinical Hospital, Mytishchi. The majority patients had moderate form (97 %), severe cases were not...

10.21055/0370-1069-2020-3-154-157 article EN cc-by Problems of Particularly Dangerous Infections 2020-10-22

Medical consortia help solve current healthcare problems. Four scientific medical institutions (GBUZ of the Moscow region “Research Institute Childhood Ministry Health Region”, Scientific Research Clinical Pediatrics and Pediatric Surgery named after Academician Yu. E. Veltishchev Federal State Autonomous Educational Institution Higher Education “Russian National University N. I. Pirogov” Russia, Budgetary “Medical Genetic Center P. Bochkov”, “Moscow Epidemiology Microbiology G....

10.31146/2949-4664-apps-2-1-6-23 article EN cc-by Archives of Pediatrics and Pediatric Surgery 2024-03-26

The purpose of the study. To evaluate results using a drug based on benzidamine hydrochloride in treatment regimens acute respiratory viral infections children today. Materials and methods. study included 875 aged 3 to 18 years with infections, which occurred mild or moderate forms, were treated an outpatient basis. During non-interventional study, retrospective analysis information from medical records was made. main group 318 who recommended therapy hydrochloride, comparison 557 received...

10.14427/jipai.2024.1.86 article EN Immunopathology Allergology Infectology 2024-01-01

Aim: to assess the efficacy of antiviral therapy in treatment acute respiratory viral infections children context contemporary clinical practice Patients and Methods: study employed a pharmacoepidemiologic approach, utilizing questionnaire survey physicians collect data on 6,116 aged 3 7 years with mild moderate infections. The group included 5,144 (84%) who received inosine pranobex. Comparison 1 654 (11%) other antivirals or immunomodulators. 2 318 (5%) did not receive any etiological...

10.32364/2618-8430-2024-7-2-12 article EN cc-by Russian Journal of Woman and Child Health 2024-01-01

Introduction. Analysis of the pathogenesis coronavirus infection caused SARS-CoV-2 indicates a significant impact hemorheological disorders on its course and outcomes. It is known that chronic cardiovascular diseases are associated with risk severe lethal outcomes both in COVID-19 other infectious diseases. Therefore, each case it necessary to study interaction mutual influence different components treatment program prescribed such patients.The purpose this work was evaluate effect...

10.36233/0507-4088-14 article EN cc-by Problems of Virology 2021-03-07

Журнал для непрерывного медицинского образования врачей Эффективность и безопасность применения фавипиравира в комплексной терапии COVID-19 легкого среднетяжелого течения 1 Федеральное бюджетное учреждение науки «Центральный научно-исследовательский институт эпидемиологии»

10.33029/2305-3496-2020-9-4-26-38 article RU Infectious diseases News Opinions Training 2020-01-01

The article discusses indications for antibiotic treatment and choice of drugs in children with acute enteric infections. Our study demonstrated the efficacy safety cefixime, oral third-generation cephalosporin. regimen Pancef (cefixime) suspension is presented.

10.21518/2079-701x-2016-1-98-101 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2016-12-30

The data on clinical, ECG, ultrasound and laboratory features of myocarditides that developed in children with acute respiratory viral infections (ARVI) have been presented this article. dynamics changes the identified possibility forming chronic pathology a one year after onset disease has shown.

10.17816/eid40658 article EN Epidemiology and Infectious Diseases 2012-06-15

Проанализировано более 30 литературных источников, содержащих данные о течении, диагностике и терапии Covid-19. Ни в одном источнике не упоминается дезинтоксикационной и/или антиоксидантной терапии. Проанализированы три клинических случая COVID-19. На основе собственной клинической практики сформирована модель патогенеза COVID-19, которая обосновывает необходимость применения препаратов – дезинтоксикантов, сорбентов антиоксидантов, как улучшающих течение, прогноз исход заболевания....

10.21055/preprints-3111722 preprint RU cc-by 2020-07-20

The article tells about the main aspects of differential diagnosis and therapy for diarrheal syndrome. components treatment indications antimicrobials in acute intestinal infections are considered. Results studies confirm efficacy safety nifuroxazide.

10.21518/2079-701x-2016-07-78-81 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2016-01-01

The article presents the results of an observational study to evaluate effectiveness COVID‑19 therapy. aim study. To etiotropic therapy in outpatient patients with COVID‑19. Materials and methods . included 244 According starting from first week disease, were divided into 3 groups: those who received favipiravir, umifenovir did not receive antiviral agents. Results median time interquartile interval before virus elimination while taking favipiravir was (3.0; 5.0) days, among – 5 7.0) without...

10.33667/2078-5631-2022-18-23-26 article EN Medical alphabet 2022-07-26

The article presents the results of a study frequency diarrheal syndrome in patients with COVID‑19. pathogenesis diarrhea and its differences from other acute respiratory infections are considered detail, including on clinical example. Objective. To registration, features pathogenetic therapy for confirmed Materials methods. 286 case histories male female aged 18–96 years old who received outpatient treatment June 2020 to February 2021 connection diagnosis COVID‑19 were analyzed. Results....

10.33667/2078-5631-2023-34-24-28 article EN Medical alphabet 2024-01-18

РУБРИКА ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ Анализ уровня цитокинов в зависимости от течения COVID-191 Ташкентская медицинская академия, 100109, г.Ташкент, Республика Узбекистан 2 Федеральное бюджетное учреждение науки «Московский научноисследовательский институт эпидемиологии и микробиологии имени Г.Н.Габричевского» Федеральной службы по надзору сфере защиты

10.33029/2305-3496-2024-13-1-15-19 article RU Infectious diseases News Opinions Training 2024-01-01

Introduction. Representatives of the family Enterobacteriaceae are ubiquitous in environment, causing severe, including opportunistic diseases immunocompromised individuals. The occurrence antibiotic-sensitive bacteria Klebsiella genus within recreational zone a water body is potent posing an epidemiologic danger to inhabitants settlement. Materials and Methods. Water samples from surface aquifers Don Temernik rivers Rostov-on-Don served as material for study. sensitivity isolates Kl....

10.47470/0016-9900-2024-103-3-234-241 article EN Hygiene and Sanitation 2024-04-10

Representatives of the genus Staphylococcus spp. occupy a leading place in etiology infections caused by opportunistic bacteria. spp., being symbionts humans and/or animals, are constantly located on surface skin and mucous membranes, which their natural habitats. The importance bacteria It is determined significant distribution population, as well among patients medical personnel, due to transient resident carrier, high adaptive potential, ability form biofilms produce enzymes that provide...

10.17816/eid632504 article EN Epidemiology and Infectious Diseases 2024-09-10

The article presents materials and results of the VAll-Russian Anniversary Congress with international participation «5P Children’s Medicine», held in Moscow on March 27-29, 2024. significance this event for development Russian pediatric medicine as asignificant world is considered framework extrapolating experience best practices, highlighting new achievements fundamental applied pediatrics.

10.31146/2949-4664-apps-2-2-4-16 article EN Archives of Pediatrics and Pediatric Surgery 2024-09-15

Objective. To evaluate the features of manifestations active Epstein–Barr virus (EBV) infection in children and to clarify possibilities etiotropic therapy. Patients methods. Seventy aged 3 7 years were included study. The main group 35 with laboratory signs EBV activity, comparison negative results. results different approaches therapy evaluated group. Results. Lymphadenopathy (71%), hyperemia posterior pharyngeal wall (100%), enlargement tonsils (74%), plaques on (51%), enanthema (46%)...

10.20953/1817-7646-2024-4-64-70 article EN Voprosy praktičeskoj pediatrii 2024-01-01

The purpose of the study . aim was to evaluate effectiveness antiviral therapy in urogenital infection caused by herpes simplex virus combination with human papillomavirus (HSV‑1, -2 and HPV) couples impaired reproductive function. Materials methods. included 149 married complaints about absence or pathological course pregnancy termination first trimester. Urogenital detected 80 couples. A 36 cases. evaluated. Results. After treatment use an antiherpetic drug who had manifestations active...

10.33667/2078-5631-2023-34-47-50 article EN Medical alphabet 2024-01-18

The article presents the results of studies microbiome features in patients with autism spectrum disorders. role microbiota as a part enteral nervous system influencing dynamics symptoms is considered. links between eating behavior and severity autistic disorders, increased permeability gastrointestinal mucosa hypoxia brain cells, nature intestinal dysbiotic clinical manifestations are shown. Taking into account presented data, optimal approaches to diagnosis therapy disorders shown, which...

10.31146/2949-4664-apps-2-1-170-181 article EN cc-by Archives of Pediatrics and Pediatric Surgery 2024-03-26

The authors present a review of the literature on peculiarities immunity in children, which may explain differences symptoms COVID-19 childhood. In tends to occur more easily than adults. However, as years pandemic, and post-pandemic period, there were quite few cases complicated course with need for hospitalization, sometimes fatal outcomes. Infants under age 1 year account highest percentage hospitalizations among children. Currently, analysis results comparing clinical manifestations...

10.31146/2949-4664-apps-2-1-96-103 article EN cc-by Archives of Pediatrics and Pediatric Surgery 2024-03-26
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