A5070530856- Click Chemistry and Applications
- Synthesis and biological activity
- Tuberculosis Research and Epidemiology
- Synthesis and Catalytic Reactions
- Pesticide and Herbicide Environmental Studies
- Organic Chemistry Cycloaddition Reactions
- Biochemical and Molecular Research
- Computational Drug Discovery Methods
- Cancer therapeutics and mechanisms
- Pesticide Residue Analysis and Safety
- Allelopathy and phytotoxic interactions
- vaccines and immunoinformatics approaches
- Multicomponent Synthesis of Heterocycles
- Pharmaceutical and Antibiotic Environmental Impacts
- Colorectal Cancer Treatments and Studies
- Synthesis and Biological Evaluation
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Analysis
- Weed Control and Herbicide Applications
- Pharmacology and Obesity Treatment
- Natural Antidiabetic Agents Studies
- Bacteriophages and microbial interactions
- Morinda citrifolia extract uses
- Synthesis of Organic Compounds
Vietnam National University Ho Chi Minh City
2023
University of Hong Kong
2023
An Giang University
2023
Inserm
2012-2020
Université de Lille
2020
Médicaments et Molécules pour Agir sur les Systèmes Vivants
2015-2020
Institut Pasteur de Lille
2015-2020
Ho Chi Minh City Medicine and Pharmacy University
2009-2015
Center for Infectious Disease Research
2014
Université Claude Bernard Lyon 1
2012-2013
Killing more than one million people each year, tuberculosis remains the leading cause of death from a single infectious agent. The growing threat multidrug-resistant strains Mycobacterium stresses need for alternative therapies. EthR, mycobacterial transcriptional regulator, is involved in control bioactivation second-line drug ethionamide. We have previously reported discovery vitro nanomolar boosters ethionamide through fragment-based approaches. In this study, we further explored...
A series of halogen containing 1,4-naphthoquinon derivatives (1-4,5a-f) were synthesized and studied for their antifungal activities against C. albicans ATCC10231, 955, T. mentagrophytes M. gypseum. The results indicate that compound 2-hydroxy-3-chloro-1,4-naphthoquinone (2), 2-(N-acetyl)- acetamido-3-chloro- 1,4-napthoquinone (3) 2-(N-acetyl)-acetamido-3-chloro- 1,4- napthoquinone (4) have potent activity. Among these promising candidates, 2 4 showed better activity than clinically drug...
Obesity is a growing global health problem, but few drugs are available for the treatment of obesity. Several classes compounds have been studied and demonstrated human lipase inhibition activity - target in obesity prevention. This study was about design, synthesis biological evaluation some synthetic chalcones as pancreatic inhibitors. FlexX software integrated LeadIT used molecular docking studies 66 chalcone derivatives. 6 derivatives with low scores (good binding affinity) were selected...
Abstract In situ generated nitrile oxides undergo 1,3‐dipolar cycloaddition with alkenes to give 2‐isoxazoline derivatives.
Diuron has been widely applied to control weeds causing serious environmental pollution. In the current study, mixed culture of three bacterial isolates, Bacillus subtilis DU1, Acinetobacter baumannii DU, and Pseudomonas sp. DUK, was investigated for diuron degradation in a packed reactor soil. The immobilization bacteria mixture rice straw increased degradation. specific rates by immobilized batch cultures from 0.38 ± 0.03 mg/L at first cycle 0.98 0.10 fourth cycle. using also carried out...
Novel chemical entities are urgently needed to develop new antibacterial agents in order tackle the increasing antibiotic resistance. This study focuses on 1,3-benzodioxole scaffold with promising biological activities literature. Five containing derivatives were synthesised from piperonal as starting material by various reactions. Their structures elucidated standard spectroscopic methods. The vitro studied agar diffusion method against 5 pathogenic strains: Escherichia coli, Pseudomonas...
The herbicide of acetochlor has been widely applied to control weeds in agricultural sector, but it is responsible for numerous environmental hazards. In the current study, we investigated effects on bacteria and microfungi communities soil. research findings revealed that used at 1.24 mg/kg inhibited growth both microfungi. Moreover, degradation half-life values were greater higher concentrations soil, from 12.3 ± 1.2 days concentration 1.0× 24.5 2.5 2.0×. augmentation P. fluorescens KT3...