A5026077616- Obsessive-Compulsive Spectrum Disorders
- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Autism Spectrum Disorder Research
- Bipolar Disorder and Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neurotransmitter Receptor Influence on Behavior
- Eating Disorders and Behaviors
- Body Image and Dysmorphia Studies
- Schizophrenia research and treatment
- Sexuality, Behavior, and Technology
- Gambling Behavior and Treatments
- Adolescent and Pediatric Healthcare
- Children's Physical and Motor Development
- Sexual function and dysfunction studies
- Neural and Behavioral Psychology Studies
- Perfectionism, Procrastination, Anxiety Studies
- Receptor Mechanisms and Signaling
- Stuttering Research and Treatment
- Cognitive and developmental aspects of mathematical skills
- Child Nutrition and Feeding Issues
- Sleep and related disorders
- Treatment of Major Depression
- Maternal Mental Health During Pregnancy and Postpartum
- Youth Substance Use and School Attendance
Fondazione Stella Maris
2012-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2022
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
1996-2013
University of Pisa
1997-2013
University of Florence
2002
Objective: A substantial portion of juvenile bipolar disorder (BD) has a comorbid attention‐deficit hyperactivity (ADHD). The aim our study was to analyze the cross‐sectional and longitudinal implications such comorbidity in children adolescents with BD. Methods: Ninety‐eight refereed patients (mean age 13.7 ± 3.0 years) diagnosis BD by Schedule for Affective Disorders Schizophrenia School‐Age Children, Present Lifetime version (K‐SADS‐PL) were followed 6 months. Results: Thirty‐seven...
Few studies have examined the impact of gender, age at onset, phenotype and comorbidity in pediatric obsessive-compulsive disorder (OCD) children. In this naturalistic study we consider these characteristics OCD framework 4 phenotypes (contamination/cleaning, order/symmetry, obsessions/checking hoarding) proposed by Leckman et al.A consecutive series 257 patients aged 13.6 +/- 2.8 years, diagnosed using a DSM-IV-based clinical interview (Schedule for Affective Disorders Schizophrenia School...
Although Attention Deficit Hyperactivity Disorder (ADHD) has been related to an increased risk for behavioral addictions, the relationship between ADHD and Internet Gaming (IGD) is still debated. The aim of this study address topic by exploring prevalence IGD in a consecutive sample youth, compared normal control group, assessing selected psychopathological cognitive features patients with without IGD. One hundred eight (mean age 11.7 ± 2.6 years, 96 males) 147 controls (NC) 13.9 3.0 114...
Summary Insight is a complex phenomenon that can be interpreted according to dimensional model. Given the controversial data of insight in obsessive–compulsive disorder (OCD), our study aimed investigate an Italian sample patients with OCD by means specific item on Yale–Brown scale (Y-BOCS) and explore possible correlations between it clinical features. One hundred seventeen out-patients DSM-IV diagnosis different comorbid psychiatric disorders were included assessed Y-BOCS, Hamilton rating...
Risperidone, an atypical neuroleptic, has been proposed for augmentation strategies in resistant obsessive-compulsive disorder (OCD). We report the results of open-label trial on use combination serotonin reuptake inhibitors (SRIs) with risperidone 20 refractory OCD outpatients. All patients had suffering from OCD, according to DSM-IV criteria, at least 2 years and various comorbid disorders. treated a SRI adequate dosages 6 months, but failed respond. Therefore, was added dosage titrated up...
The aim of this study was to assess efficacy aripiprazole augmentation serotonin reuptake inhibitor (SRI) treatment in adolescents with obsessive-compulsive disorder (OCD) who did not respond 2 initial trials SRI monotherapy. A consecutive series 39 (28 males and 11 females; age range, 12 18 years; mean age, 14.6 ± 1.2 years), OCD diagnosed based on a clinical interview according the Diagnostic Statistical Manual Mental Disorders, Fourth Edition criteria, were included. final dosage 12.2 3.4...
Tourette's disorder (TD) in children and adolescents is frequently co-morbid with attention-deficit/hyperactivity (ADHD). Dopamine-blockers are the first line treatment for TD, whereas dopamine-agonists, such as stimulants, gold-standard of ADHD. These contrasting effects supported concerns about risk that stimulants treating ADHD may trigger or worsen tics. Aripiprazole, a partial dopamine agonist, acts an antagonist at D2 receptors hyperdopaminergic conditions displays agonist properties...
The similarities between the serotonin (5-HT) transporter in both human platelets and brain permit us to investigate this structure patients with different psychiatric disorders. Several reports have shown abnormalities of 5-HT transporter, by means measurement uptake or 3H-imipramine binding, obsessive-compulsive disorder (OCD). availability ligand 3H-paroxetine, a selective reuptake inhibitor, label promoted evaluate binding 3H-paroxetine 18 drug-free OCD. results, showing that had lower...
Background: This study on a large sample of unselected, consecutive children and adolescents referred to third-level hospital who received diagnosis bipolar disorder (BD) was aimed at exploring whether childhood-onset BD, as compared with adolescent-onset presents specific clinical features in terms severity, functional impairment, course, prevalent mood, pattern co-morbidity, treatment outcome. Methods: A total 136 patients, 81 males (59.6%) 55 females (40.4%), mean age 13.5 ± 2.9 years,...
The present study reports the results of an open-label trial on use combination olanzapine (an atypical antipsychotic) serotonin reuptake inhibitors (SRIs) in 26 resistant outpatients affected by obsessive-compulsive disorder (OCD). All patients had been suffering from OCD, according to DSM IV criteria, for at least 2 years and different comorbid disorders; they treated with SRI adequate dosages 6 months, or tried augmentation strategies no poor response. As a result, was added continued 1...
ABSTRACT Introduction: The high percentage (between 40% and 60%) of resistance to first-line drugs, such as clomipramine or selective serotonin reuptake inhibitors, is a major problem in the pharmacologic management obsessive-compulsive disorder (OCD). In these cases, different strategies have been employed with controversial outcomes. meager information available on association two serotonergic drugs prompted us explore possible effectiveness tolerability citalopram+clomipramine resistant...
Article AbstractObjective: Two main patterns of comorbidity have been described in bipolar disorder children and adolescents: the first including preexisting attention-deficit/hyperactivity (ADHD) related disruptive behavior disorders second anxiety disorders, namely, association co-occurring multiple usually predating onset bipolarity. This study was aimed at exploring whether ADHD may exhibit different pathways to specific phenotypes.Method: We compared 49 youths (7 18 years) with +...
Attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant (ODD) are frequently co-occurring in youth, but data about the pharmacological management of this comorbidity scarce, especially when impulsive aggression is prominent. Although stimulants first-line medication for ADHD, second-generation antipsychotics, namely, risperidone, used. We aimed to assess effectiveness safety monotherapy with stimulant methylphenidate (MPH) risperidone a consecutive sample 40 drug-naive male...
Emotional dysregulation (ED) is currently the most frequently used term to describe children with an impaired regulation of emotional states. Recent research studies speculate whether ED may be a neurodevelopmental disorder itself, shared risk factor, or common key feature several psychiatric disorders, including, among others, attention deficit hyperactivity (ADHD), and bipolar spectrum disorders (BSD). The association between ADHD one main reasons misconceptions in definition boundaries...