A5090063999- Research on Leishmaniasis Studies
- Nanoparticles: synthesis and applications
- Trypanosoma species research and implications
- Toxin Mechanisms and Immunotoxins
- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- Graphene and Nanomaterials Applications
- Veterinary medicine and infectious diseases
- Helicobacter pylori-related gastroenterology studies
- Immunotherapy and Immune Responses
- Nanoparticle-Based Drug Delivery
- Vector-borne infectious diseases
- Insect Pest Control Strategies
- Moringa oleifera research and applications
- Mesenchymal stem cell research
- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Nerve injury and regeneration
- Insect and Pesticide Research
- Tissue Engineering and Regenerative Medicine
- biodegradable polymer synthesis and properties
- Polymer Surface Interaction Studies
- Burkholderia infections and melioidosis
- Monoclonal and Polyclonal Antibodies Research
- Nigella sativa pharmacological applications
National Nuclear Research Center
2023-2024
Bielefeld University
2024
Yıldız Technical University
2013-2023
Ministry of Healthcare
2023
World Health Organization - Afghanistan
2023
Istanbul Technical University
2018
University of Veterinary and Animal Sciences
2018
Istanbul University
2015
Azerbaijan Medical University
2015
Institute of Scientific and Technical Information
2015
Abstract: Leishmaniasis is a protozoan vector-borne disease and one of the biggest health problems world. Antileishmanial drugs have disadvantages such as toxicity recent development resistance. One best-known mechanisms antibacterial effects silver nanoparticles (Ag-NPs) production reactive oxygen species to which Leishmania parasites are very sensitive. So far no information about Ag-NPs on tropica parasites, causative agent leishmaniasis, exists in literature. The aim this study was...
Abstract Biocatalysis has emerged in recent decades toward a widely applied catalysis technology the chemical industry. In particular fine chemicals and pharmaceuticals industries benefit from advantages of biocatalysis, which made its way to dominating industrial core for manufacturing chiral molecules. However, often biocatalysis is still certain extent away having solved all challenges being needed “perfect process technology”. Among existing are, e.g., stability under conditions easy...
Canine parvovirus 2 (CPV-2) remains a significant worldwide canine pathogen and the most common cause of viral enteritis in dogs. The 1 L15 7 peptides overlap each other with QPDGGQPAV residues (7-15 VP2 capsid protein CPV) is shown to produce high immune response. PLGA nanoparticles were demonstrated have special properties such as; controlled antigen release, protection from degradation, elimination booster-dose enhancing cellular uptake by presenting cells. Nevertheless, there no study...
A total of 1,030 patients, 40.2% men and 59.8% women, identified during the period October 1998 to November 2002 as having cutaneous leishmaniasis (CL), were studied; 1,431 lesions in patients. One lesion was present 80.7% The size (longest axis) 13.6 mm (standard, 12.1 mm; range 3-150 mm). Most papular type (51.2%), although several atypical clinical presentations CL observed. duration disease ranged between 1 72 mo (mean duration, 10.8 mo). suspicion confirmed by observation amastigotes on...
In general there is an urgent current need to switch from fossil-based materials renewable sources and this also the case for production of alkenes with a chain length...
The purpose of this study was to show the efficacy olfactory stem cells for injured facial nerve reconstruction in a rat model.Olfactory were isolated from mucosa human participants. A 2-mm excision performed on right all rats. Reconstruction with conduit group 1 (n = 9); and phosphate-buffered saline 2 labeled cell 3 9). Rats followed whisker movements electroneuronography (ENoG) analyses.The whisker-movement scores significantly different other groups (p < .001). ENoG showed that amplitude...
Objective: To prepare and characterize polycaprolactone (PCL) nanoparticles loaded with sonicator fragmented (SLA) freeze- thaw Leishmania antigens (FTLA) to investigate the in vitro immunogenicity of antigen-encapsulated calcium phosphate adjuvant. Methods: The water/oil/water binary emulsion solvent evaporation method was used synthesize antigen-loaded PCL nanoparticles. Particles were characterized by scanning electron microscopy zeta potential measurements. Their cytotoxicity J774...
A sensitive microcapillary culture method (MCM) was developed for rapid diagnosis of cutaneous leishmaniasis (CL). The MCM is superior to the traditional (TCM) as determined by smaller inoculum size, higher sensitivity detection promastigotes, and more time emergence promastigotes. With lesion amastigote loads from grade III 0, positive rates periods promastigote were 3-4-fold faster with than TCM, e.g., 83-97% in 4-7 days versus 20-40% 15-30 (P = 0.0001). Pco(2) lower Po(2) pH presumably...
One of the biggest challenges in fight against cancer is early detection. Early diagnosis vital, but there are some barriers such as economic, cultural, and personal factors. Considering disadvantages radiological imaging techniques or serological analysis methods used diagnosis, being expensive, requiring expertise, time-consuming, a need to develop faster, more reliable, cost-effective diagnostic for use diagnosis. Exosomes, which responsible intercellular communication with sizes ranging...
Abstract Research on the conjugates of synthetic polyelectrolytes with antigenic molecules, such as proteins, peptides, or carbohydrates, is an attractive area due to their highly immunogenic character in comparison classical adjuvants. For example, polyacrylic acid (PAA) a weak polyelectrolyte and has been used several biomedical applications immunological studies, drug delivery, enzyme immobilization. However, our knowledge, there are no studies that document immune-stimulant properties...
This study is the first to investigate antileishmanial activities of Nigella sativa oil (NSO) entrapped poly-