A5090854661- Photosynthetic Processes and Mechanisms
- Phytase and its Applications
- Plant Disease Management Techniques
- Nitrogen and Sulfur Effects on Brassica
- Plant Reproductive Biology
- Plant tissue culture and regeneration
- Nematode management and characterization studies
- Occupational and environmental lung diseases
- Plant nutrient uptake and metabolism
- S100 Proteins and Annexins
- Plant biochemistry and biosynthesis
- Legume Nitrogen Fixing Symbiosis
- Advanced Glycation End Products research
- Plant-Microbe Interactions and Immunity
- Plant Pathogenic Bacteria Studies
- Animal Virus Infections Studies
- Bacteriophages and microbial interactions
- Seed Germination and Physiology
- Plant Stress Responses and Tolerance
- Studies on Chitinases and Chitosanases
- Polyamine Metabolism and Applications
- Forest Management and Policy
- GABA and Rice Research
- Toxin Mechanisms and Immunotoxins
- Plant Disease Resistance and Genetics
University of Georgia
2022-2024
Florida Department of Agriculture and Consumer Services
2024
University of Hawaiʻi at Mānoa
2011-2017
University of Hawaii System
2013-2017
University of Hawaii Cancer Center
2013
Cancer Center of Hawaii
2013
Micronesia Conservation Trust
2011
University of Arkansas at Monticello
2011
US Forest Service
2011
Human malignant mesothelioma (MM) is an aggressive cancer linked to asbestos and erionite exposure. We previously reported that High-Mobility Group Box-1 protein (HMGB1), a prototypic damage-associated molecular pattern, drives MM development sustains progression. Moreover, we demonstrated targeting HMGB1 inhibited cell growth motility in vitro, reduced tumor vivo, prolonged survival of MM-bearing mice. Ethyl pyruvate (EP), the ethyl ester pyruvic acid, has been shown be effective inhibitor...
Abstract The tree legume Leucaena leucocephala contains a large amount of toxic nonprotein aromatic amino acid, mimosine, and also an enzyme, mimosinase, for mimosine degradation. In this study, we isolated 1,520-bp complementary DNA (cDNA) mimosinase from L. characterized the encoded enzyme mimosine-degrading activity. deduced acid sequence coding region cDNA was predicted to have chloroplast transit peptide. nucleotide sequence, excluding peptide, codon optimized expressed in Escherichia...
Leucaena leucocephala (leucaena) is a tropical tree-legume, known for its high level of tolerance to various stress conditions including drought and diseases. We hypothesised that leucaena contains specific set genes abiotic biotic stresses, which may be either absent or not expressed in other legumes are susceptible these conditions. Interspecies suppression subtractive hybridisation (iSSH) was used identify some leucaena-specific using cDNAs from Acacia confusa (acacia) as the tester...
The seeds of Jatropha curcas (jatropha), which contain 27-40% oil, are an important source for bio-diesel production. For making production profitable, it is desirable to use the seed meal generated as a byproduct producing animal feed. Although jatropha contains 50-62% protein, not suitable feed without additional processing because one proteins, curcin, toxin that inhibits protein synthesis. A rapid detection method curcin will be useful in determining any remnant processed products....
The resistance (R) gene family in plants is a vital component of the plant defense system, enabling host against pathogens through interactions with pathogen effector proteins. These R genes often encode nucleotide-binding (NB-ARC or N) and leucine-rich-repeat (LRR L) domains, collectively forming NLR protein family. proteins have been widely explored crops from Poaceae Brassicaceae, but limited studies are available for other families, including Fabaceae. To address this gap, we conducted...
The soil-borne pathogens, particularly Fusarium oxysporum f. sp. niveum (FON) and southern root-knot nematode (RKN, Meloidogyne incognita) are the major threats to watermelon production in southeastern United States. role of soil micronutrients on induced resistance (IR) plant diseases is well-documented soil-based media. However, media do not allow us determine contribution individual induction IR. In this manuscript, we utilized hydroponics-medium assess effect controlled application...
Abstract High-Mobility Group Box 1 (HMGB1) is a chromatin-associated protein critically involved in nucleosome assembly. During cell necrosis, HMGB1 first translocated from the nucleus to cytoplasm, and then passively released extracellular space, where it initiates propagates inflammatory response. Immune cells (e.g. macrophages) cancer are also able actively secrete HMGB1. Extracellular therefore considered crucial molecule for both chronic inflammation development, promising therapeutic...
In plants, the final step of cysteine formation involves addition sulfide to O ‐acetylserine (OAS) and release acetate, catlyzed by (thiol) lyase (OASTL). The purpose this study was isolate characterize recombinant OASTL from Leucaena leucocephala (leucaena), a protein‐rich legume used as fodder. contains toxic, nonprotein amino acid, mimosine, which is also produced OASTL. order understand function enzyme, we first studied synthesis. cDNA for cytosolic obtained through interspecies...
Abstract Leucaena leucocephala (leucaena) is an important agroforestry tree of tropics and subtropics due to its protein rich foliages, ability grow on poor soils, high level tolerance various stresses including drought diseases. We hypothesized that leucaena have a unique set genes which confer abiotic biotic these are either absent or not expressed in other legumes susceptible stress conditions. Interspecies suppression subtractive hybridization (iSSH) was performed identify some from...
The soil-borne pathogens, particularly Fusarium oxysporum f. sp. niveum (FON) and southern root-knot nematode (RKN, Meloidogyne incognita) are the major threat to watermelon production in south-eastern United States. role of soil micronutrients on induced resistance (IR) plant diseases is well-documented soil-based mediums. However, mediums limit determination role(s) individual IR. In this manuscript, we utilized hydroponics assess effect controlled application micronutrient, including iron...