A5013074081- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- DNA and Nucleic Acid Chemistry
- Sports injuries and prevention
- Cancer therapeutics and mechanisms
- Knee injuries and reconstruction techniques
- Bacteriophages and microbial interactions
Johns Hopkins Medicine
2025
Johns Hopkins University
2025
Phoenix (United States)
2023
WinnMed
2022-2023
Mayo Clinic Hospital
2023
Mayo Clinic in Florida
2022-2023
DNA supercoiling (SC), the over- and under-winding of DNA, is generated by transcription as described in twin-domain model. Conversely, SC also impacts through torsional stress. therefore regulates independent factor binding, classic protein-based regulatory mechanism, particularly context chromosomal topological domains actions topoisomerases. SC-coupled has inspired several computational models, but a systematic quantitative assessment parameters controlling this complex interplay missing....
When used appropriately, the minimal clinically important difference (MCID) provides a powerful tool for identifying meaningful improvements brought about by given treatment, offering more relevant information than frequentist statistical analysis. However, recent studies have shown inconsistent derivation methods and use of MCIDs. The goal this study was to report rate patient-reported outcome measures (PROMs) MCIDs in literature assess how has changed over time.All articles published 2010...
Abstract Introduction Minimum clinically important differences (MCIDs) are critical to understanding changes in patient-reported outcome measure (PROM) scores after total joint arthroplasty (TJA). The usage and adoption of MCIDs not been well-studied. This study was performed IDENTIFY trends PROM MCID use TJA over the past decade. Methods All articles published calendar years 2010 2020 CORR, JBJS, Journal Arthroplasty were reviewed. Articles relating clinical outcomes primary hip (THA) or...