A5022275850- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Muscle and Compartmental Disorders
- Potassium and Related Disorders
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Acute Kidney Injury Research
- Electrolyte and hormonal disorders
- Respiratory Support and Mechanisms
- Renal function and acid-base balance
- Renal Transplantation Outcomes and Treatments
- Cardiovascular Function and Risk Factors
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis Viruses Studies and Epidemiology
- Mechanical Circulatory Support Devices
- Poisoning and overdose treatments
- Congenital Heart Disease Studies
- Cardiac Arrest and Resuscitation
- Atrial Fibrillation Management and Outcomes
- Organ Donation and Transplantation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Flavonoids in Medical Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Blood groups and transfusion
- Medicinal Plant Research
Allegheny Health Network
2024-2025
Wellesley College
2024
University of Minnesota
2021-2024
Southern Illinois University School of Medicine
2024
McMaster University
2024
University of Virginia Health System
2014-2023
Khyber Teaching Hospital
2023
University of Virginia
2020-2023
Doctors Hospital
2023
Mayo Clinic
2021
Volatile anesthetics are currently believed to cause unconsciousness by acting on one or more molecular targets including neural ion channels, receptors, mitochondria, synaptic proteins, and cytoskeletal proteins. Anesthetic gases isoflurane bind microtubules (MTs) dampen their quantum optical effects, potentially contributing causing unconsciousness. This possibility is supported the finding that taxane chemotherapy consisting of MT-stabilizing drugs reduces effectiveness anesthesia during...
This article explores the potential of phytochemicals as immunomodulatory agents in cancer therapy, bridging gap between traditional plant-based medicine and modern oncological treatments. Phytochemicals, including flavonoids, alkaloids, terpenoids, polyphenols, have demonstrated significant properties that can enhance immune system function promote anti-tumor responses. These bioactive compounds work by modulating key signaling pathways, cell activation, cytokine production, tumor...
Erectile dysfunction falls under one of three main categories when evaluating male sexual dysfunction; other two include, low libido and ejaculatory disorders, both which are not included in the scope this paper. This paper will review guidelines for Dysfunction (ED) with aim to increase awareness amongst primary care clinicians signs symptoms ED, how manage patients ED community setting.
Atrial fibrillation (AF) is a low-flow state and may underestimate aortic stenosis (AS) severity. Single-high Doppler signals (HS) consistent with severe AS (peak velocity ≥4 m/s or mean gradient ≥40 mm Hg) are averaged down in current practice. The objective for the study was to determine significance of HS AF low-gradient (LGAS). One thousand five hundred forty-one patients valve area ≤1 cm2 left ventricular ejection fraction ≥50% were identified classified as high-gradient (HGAS) (≥40...
Introduction: Hypertensive disorders of pregnancy (HDP) increase long-term cardiovascular risk, yet adherence to postpartum follow-up is poor, particularly among women facing socioeconomic barriers. This study explores how factors such as race, social determinants health (SDOH), substance use, and admissions NICU correlate with current screening recommendations. Hypothesis: We hypothesize that disparities in race SDOH influence guidelines. Additionally, we high-risk may contribute lapses...
Lyme neuroborreliosis has several different clinical manifestations in children, of which facial nerve palsies, meningitis and radiculopathies are the most common. Transverse myelitis (TM) secondary to disease been reported rare occasions, typically presenting with severe weakness, sensory abnormalities autonomic dysfunction. We present case a 16-year-old male who developed acute left peripheral palsy longitudinal extensive TM disease. Remarkably, patient only mild symptoms back pain absence...
Iodinated contrast agents are well tolerated in ESRD patients. Certain types of ICM, i.e., LOCM and the nonionic associated with better safety profiles. Current available evidence, although not optimal, does support need for additional hemodialysis ICM removal to preserve residual renal function or treat other potential toxicities ICM. However, limiting exposure is a prudent measure patients given ICM’s toxicity; close monitoring poor cardiac also recommended subjects receiving higher doses...
Introduction Infections account for 8% of the total mortality in ESKD patients (1). are at increased risk infectious complications due to their immunosuppressed status. Metabolic uremia cause abnormalities monocyte and neutrophil function, as well antigen processing, antibody formation cell mediated immune responses (2). The effects on vaccine efficacy include lower seroconversion rate, peak titers faster decline titers. Consequently, Centers Disease Control Prevention (CDC) United States...
Grading severity of AS in AF is complicated by varying stroke volumes associated with fluctuating maximum velocities and pressure gradients across the aortic valve. Current guidelines recommend averaging five continuous‐wave peak velocity mean gradient ( MG ) Doppler signals valve when estimating . However, it unknown grading how average multiple vs highest signal compares to patient normal sinus rhythm. We present a series patients who had two echocardiograms performed within 2‐4 months...
Symptomatic pleural effusion secondary to pleuroperitoneal communication in patients undergoing peritoneal dialysis (PD) occurs approximately 2% of continuous ambulatory PD. The classic presentation is that a low-protein, high-glucose aspirate consistent with the high dextrose concentrations present standard PD fluids, hence name sweet hydrothorax. Nevertheless, increasing use icodextrin calls for an innovative bedside diagnostic approach because does not contain after all. We describe...