This study describes a green synthesis method for silver nanoparticles (AgNPs) using autochthonous "Mollar de Elche" pomegranate peel extract and optimized through Python-programmed Box-Behnken design (BBD) created specifically the work. The bioactive compounds in pomegranate, particularly punicalagin, serve as effective reducing stabilizing agents. BBD was used to analyze effects of dependent variables such nitrate concentration, temperature on responses hydrodynamic diameter,...

Abstract Rose petals may involve high water contact angles together with drop adhesion which are antagonistic wetting properties. Petal surfaces have a cuticle is generally considered continuous, hydrophobic lipid coating. The peculiar properties of rose not fully understood and been associated surface roughness at different scales. Here, the chemical structural features natural upper lower petal analyzed by atomic force microscopy (AFM). Both statistically equivalent very all scales from 5...

Glioblastoma (GBM), characterized by fast growth and invasion into adjacent tissue, is the most aggressive cancer of brain origin. Current protocols, which include cytotoxic chemotherapeutic agents, effectively treat localized disease; however, these therapies present side effects due to high doses administered. Therefore, more efficient ways drug delivery have been studied reduce therapeutic exposure patients. We isolated fully small extracellular vesicles (EVs) from seven patient-derived...

Neurosensory disorders such as pain and pruritus remain a major health problem greatly impacting the quality of life, often increasing risk mortality. Current pre-clinical models to investigate dysfunction sensory neurons have shown limited clinical translation, in part, by failing mimic compartmentalized nociceptor anatomy that exhibits central compartment containing soma peripheral one harboring axon endings with distinct molecular cellular environmental composition. Thus, there is need...

Pancreatic Ductal Adenocarcinoma (PDAC), is the most common aggressive cancer of pancreas. The standard care PDAC includes tumor resection and chemotherapy, but lack early diagnosis limited response to treatment worsens patient's condition. In order improve efficiency we look for more efficient systems drug delivery. We isolated fully characterized small Extracellular Vesicles (EVs) from RWP-1 cell line. Our study indicates that direct incubation method was loading protocol a minimum total...

The use of diverse Ag-based nanoparticulated forms has shown promising results in controlling viral propagation. In this study, a commercial nanomaterial consisting ceramic-coated silver nanoparticles (AgNPs) was incorporated into thermoplastic polyurethane (TPU) plates using an industrial protocol, and the surface composition, ion-release dynamics viricidal properties were studied. characterization by FESEM-EDX revealed that molar composition ceramic material 5.5 P:3.3 Mg:Al facilitated...

Sound propagation velocity of surface acoustic waves (SAWs) and bulk (BAWs) has been investigated by means high resolution Brillouin spectroscopy. The results show a linear dependence the BAW with Al concentration. There is no relevant influence substrate chosen in BAWs AlxGa1−xN thin films. SAW epitaxially grown AlN clearly lower than observed one prepared reactive dc magnetron sputtering. Numerical simulation are compared experimental results.

Several mechanisms have been revised to explain the aggregation of metal adsorbates on a $7\ifmmode\times\else\texttimes\fi{}7$ reconstructed Si(111) surface. Some them are based high mobility incident particles, while others collect nonlocal weak or moderate interactions among adsorbates. The adsorbate aggregation, which has characterized via temporal evolution surface occupation and monomer cluster density ratios, studied for each mechanism through kinetic Monte Carlo simulations as well...

In this article, the authors developed a topographic image processing procedure based on polynomial interpolating functions for studying growth of thin films at nanoscale. Using atomic force microscopy images as input proposed procedure, obtained surface slope distributions different thicknesses (2–60nm) evaporated Au(111) well thickness dependence mean slope. The scaling exponents [namely, exponent β=0.70±0.02 and dynamic one 1∕z=0.004±0.013 that determine roughness (σ) size features (ξ)...

Este trabajo estudia el papel desempeñado por las comisiones de nombramientos y retribuciones (CNR) en diseño políticas retributivas los consejeros ejecutivos empresas españolas cotizadas. Se analiza si la independencia relevancia CNR afectan a remuneraciones percibidas ejecutivos. Los resultados obtenidos, contrariamente lo esperado, ofrecen indicios que tanto como CNR, aproximada esta última través participación accionarial sus miembros su tamaño términos relativos al del consejo,...

The Spanish Code of Best Practice, Olivencia Code, contains 23 recommendations regarding the composition, size and operating characteristics Board Directors that aim to increase its supervisory duty. This paper analyzes market reaction announcements compliance with Practice made by firms. It also tries determine how different firm may explain these excess returns. results obtained indicate reacts positively firms when they imply a major restructuring Directors, while no wealth effects are...

Este trabajo analiza la influencia de estructura gobierno corporativo sobre cuantia y composicion las retribuciones los consejeros en empresas cotizadas. Se evalua si que presentan estructuras con una mayor capacidad supervisora aplican politicas retributivas caracterizadas por moderacion salarial el peso variables. Los resultados sugieren que, junto tamano rentabilidad empresarial, determinados aspectos como son concentracion accionarial, participacion accionarial o existencia comisiones...

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The scaling exponents of interface width and coarsening evaporated gold films with thickness from 30 to 1800 nm were obtained two-dimensional measurements on scanning tunneling microscopy (STM) images are presented here. lateral size protrusion the surface increases a constant exponent n≈1/3. grows in two stages. final stage starts at ≈60 corresponds time β≈1/3 slope morphology. Scaling compared those models for high epitaxial growth polycrystalline film growth, all predict To help choice...

In order to unfold the components of interface width $w$ a columnar growth we measured by scanning tunneling microscopy parameters that define surface-protrusion (SP) shapes and their fluctuations in paradigmatic Au thin film growth. The profiles SP sections can be fitted parabolas $y=a\ensuremath{-}b{x}^{2}$. scaling shape mean as well is obtained. These allow synthesis height distribution curve, separation at surface. value slope paraboloid section borders maintained constant during An...

The decomposition of the surface morphology films into well-defined elements, which are spatially distributed, allows us to obtain a versatile set parameters describe element shape. roughness is explicitly expressed in terms such shape parameters. Based on that, thickness dependence resulting for competitive columnar growth evaporated Au[111] thin was predicted, exhibiting good agreement with experimental data. expression subsequently generalized wider functional systems attractive...