A5101851897- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- Advanced ceramic materials synthesis
- Shape Memory Alloy Transformations
- Breast Lesions and Carcinomas
- High-Velocity Impact and Material Behavior
- Fatigue and fracture mechanics
- Metallurgy and Material Forming
- AI in cancer detection
- Numerical methods in engineering
- Digital Radiography and Breast Imaging
- Titanium Alloys Microstructure and Properties
- Radiomics and Machine Learning in Medical Imaging
- Nuclear and radioactivity studies
- High Temperature Alloys and Creep
- Colorectal Cancer Screening and Detection
- Cancer Immunotherapy and Biomarkers
- Estrogen and related hormone effects
- Cancer Risks and Factors
- Innovations in Concrete and Construction Materials
- Cancer Cells and Metastasis
- Breast Implant and Reconstruction
- Microstructure and Mechanical Properties of Steels
- Medical Imaging Techniques and Applications
- PI3K/AKT/mTOR signaling in cancer
Tohoku Medical and Pharmaceutical University
2017-2024
South Texas Accelerated Research Therapeutics
2019-2021
Start Treatment & Recovery Centers
2019-2021
Tohoku Medical and Pharmaceutical University Hospital
2021
International University of Health and Welfare
2018
Tohoku University Hospital
2005-2018
The Cancer Institute Hospital
2018
Kyoto University
2018
University of Tsukuba
2018
Tohoku University
2005-2017
The status of tumor-infiltrating lymphocytes (TILs) has been recently proposed to predict clinical outcome patients with breast cancer. We therefore studied the prognostic significance CD8(+) TILs and FOXP3(+) in residual tumors after neoadjuvant chemotherapy (NAC) alterations these parameters before NAC triple-negative cancer (TNBC).One hundred thirty-one TNBC who received at three institutions were examined. TIL biopsy specimens evaluated by double-staining immunohistochemistry. was...
Abstract Notch signaling is required for vascular development and tumor angiogenesis. Although inhibition of the ligand Delta-like 4 can restrict growth disrupt neovasculature, effect inhibiting receptor function on angiogenesis has yet to be defined. In this study, we generated a soluble form Notch1 (Notch1 decoy) assessed its in vitro vivo. decoy expression reduced stimulated by binding three distinct ligands inhibited morphogenesis endothelial cells overexpressing Notch4. Thus, functioned...
<h3>Importance</h3> Mammography has limited accuracy in breast cancer screening. Ultrasonography, when used conjunction with mammography screening, is helpful to detect early-stage and invasive cancers for asymptomatic women dense nondense breasts. <h3>Objective</h3> To evaluate the performance of adjunctive ultrasonography according differences density. <h3>Design, Setting, Participants</h3> This study a secondary analysis Japan Strategic Anti-cancer Randomized Trial. Between July 2007...
In the present study, we searched for genetic alterations of entire coding region PTEN/MMACl, a recently isolated candidate tumor suppressor gene, in 178 specimens from Japanese patients with various malignant tumors by polymerase chain reaction‐single strand conformation polymorphism method. The samples consisted 11 glioblastoma multiformes (GBMs), 14 astrocytomas, 47 breast cancers, 25 non‐small cell lung 9 small 8 pancreatic 24 renal carcinomas, 20 ovarian and metastatic organs. Only one...
The age-specific sensitivity of a screening program was investigated using population-based cancer registry as source false-negative cases. A for breast run either clinical examinations (CBE) alone or mammography combined with CBE in the Miyagi Prefecture from 1997 to 2002. Interval cancers were newly identified by linking records estimate number cases program. Among 112 071 women screened CBE, detected cancers, and 289, 22 92.9%, respectively, based on reports participating municipalities....
ObjectiveThe aim of this study was to evaluate the reliability information obtained by core needle biopsy (CNB).
The significantly low prevalence of atherosclerotic cardiovascular disease in premenopausal women has been noted, and postmenopausal hormone replacement therapy (HRT) is associated with protection from this disease. aim study was to investigate the effects estrogen progestin on growth-factor-induced vascular smooth muscle cell (VSMC) proliferation migration vitro.Two lines human female aortic cells (AOSMCs) were used for study. DNA synthesis evaluated by [3H]thymidine incorporation into...
ObjectiveThe objective of the Japan Strategic Anti-cancer Randomized Trial was to verify efficacy use ultrasonography in breast cancer screening among women aged 40–49 years. The purpose this paper report design and recruitment result study.
A feasibility study of a remote radiation monitoring system using an autonomous unmanned helicopter, mounted with detector and three CCD cameras, was carried out for surveying the dose-rate distribution environmental radiation. This can fly to destinations return under automatic operation, measure data during flight, immediately transmit data, including images, station on ground. It is also possible monitor map computer display in real time. Flight tests confirmed that fluctuations ground,...
The relationship between phase transformation and electric resistivity of Ti-42.6Ni-7Cu SMA was investigated. In the isothermal tensile tests, stress—strain curve shows large hysteresis nonlinearity, whereas resistivity—strain can be fitted by linearity. SMAs determined from volume fractions martensitic austenitic phases. This characteristics leads to that resistance is used as a parameter strain SMAs. A actuator using feedback control system proposed, which retain positioning at any...
Abstract This article updates readers as to what is new in the Japanese Breast Cancer Society Clinical Practice Guidelines for Screening and Diagnosis, 2018 Edition. cancer screening issues are covered, including matters of breast density possible supplemental modalities, along with appropriate pre-operative/follow-up diagnostic imaging tests. Up-to-date clinical practice guidelines diagnosis should help provide patients clinicians not only evidence-based options, but also accurate balanced...
Abstract This article provides updates to readers based on the newly published Japanese Breast Cancer Society Clinical Practice Guidelines for Screening and Diagnosis, 2022 Edition. These guidelines incorporate latest evaluation of evidence from studies diagnostic accuracy. For each clinical question, outcomes benefits harms were established, qualitative or quantitative systematic reviews conducted. Recommendations determined through voting by a multidisciplinary group, documented facilitate...