Hiroyuki Hasegawa

ORCID: 0000-0002-7138-780X
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Research Areas
  • Metal and Thin Film Mechanics
  • Crystallization and Solubility Studies
  • Organic and Molecular Conductors Research
  • X-ray Diffraction in Crystallography
  • Porphyrin and Phthalocyanine Chemistry
  • Perovskite Materials and Applications
  • Diamond and Carbon-based Materials Research
  • Neurotransmitter Receptor Influence on Behavior
  • Semiconductor materials and devices
  • Organic Electronics and Photovoltaics
  • Conducting polymers and applications
  • Photoreceptor and optogenetics research
  • Magnetism in coordination complexes
  • Tryptophan and brain disorders
  • Force Microscopy Techniques and Applications
  • Molecular Junctions and Nanostructures
  • GaN-based semiconductor devices and materials
  • Crystallography and molecular interactions
  • Remote Sensing and LiDAR Applications
  • Satellite Image Processing and Photogrammetry
  • Advanced Surface Polishing Techniques
  • Advanced machining processes and optimization
  • Receptor Mechanisms and Signaling
  • Polyamine Metabolism and Applications
  • Electrochemical Analysis and Applications

Saga University
2010-2024

University of Yamanashi
2024

University of Yamanashi Hospital
2022-2024

University of Shimane
2023-2024

Shimane University
2019-2024

National Institute of Information and Communications Technology
2006-2023

Japan Advanced Institute of Science and Technology
2022

Dai Nippon Printing (Japan)
2022

Chubu Electric Power (Japan)
2021

Nihon University
1995-2020

SP-22 is a mitochondrial antioxidant protein in bovine adrenal cortex. The homologous to thioredoxin peroxidase and other proteins. It protects radical-sensitive enzymes from oxidative damage by radical-generating system (Fe2+/dithiothreitol) the presence of small amount serum. In this study we purified second with Mr 11,777, which cooperates protect glutamine synthetase proteins Fe2+/dithiothreitol-mediated damage. Without SP-22, had no protecting activity. We determined amino acid...

10.1111/j.1432-1033.1997.t01-1-00052.x article EN European Journal of Biochemistry 1997-10-01

10.1016/s0924-2716(99)00006-4 article EN ISPRS Journal of Photogrammetry and Remote Sensing 1999-07-01

Introduction of an ethylenedithio group into amphiphilic bis(tetrathiafulvalene) annulated macrocycle results in the formation organogels which produce nanodot-array structures Langmuir–Blodgett films (see picture). Chemical oxidation sulphur-containing π-electron system afforded size-controllable electrically conducting nanodot structures. Supporting information for this article is available on WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z502336_s.pdf or from author. Please...

10.1002/anie.200502336 article EN Angewandte Chemie International Edition 2005-10-17

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotoinduced Coagulation of Au NanocolloidsNaoki Satoh, Hiroyuki Hasegawa, Kaoru Tsujii, and Keisaku KimuraCite this: J. Phys. Chem. 1994, 98, 8, 2143–2147Publication Date (Print):February 1, 1994Publication History Published online1 May 2002Published inissue 1 February 1994https://pubs.acs.org/doi/10.1021/j100059a029https://doi.org/10.1021/j100059a029research-articleACS PublicationsRequest reuse permissionsArticle...

10.1021/j100059a029 article EN The Journal of Physical Chemistry 1994-02-01

Serotonin [5-hydroxytryptamine (5-HT)] is a major therapeutic target of psychiatric disorders. Tryptophan hydroxylase (TPH) catalyzes the rate-limiting reaction in biosynthesis 5-HT. Two isoforms (TPH1 and TPH2) having tryptophan hydroxylating activity were identified. Association studies have revealed possible TPH1 involvement conditions behavioral traits. However, mRNA was reported to be mainly expressed pineal gland periphery barely detected brain. Therefore, contribution brain 5-HT...

10.1523/jneurosci.1835-05.2006 article EN cc-by-nc-sa Journal of Neuroscience 2006-01-11

Trifluoromethylphenyl-substituted phthalimide derivatives favorably form triboluminescence (TL) active noncentrosymmetric crystals. Oligothienyl-, oligophenyl-, and naphthyl-substituted were successfully developed as a series of metal free TL compounds. X-ray crystal structure analyses bithienyl naphthyl revealed layer structures in the same direction. Introduction suitable electron rich π-units such thienyl groups enhances their photoluminescence characteristics, colors can be also...

10.1021/acs.joc.5b02191 article EN The Journal of Organic Chemistry 2015-12-11

A highly conducting partially oxidized salt of TPP[Co(Pc)(CN)2 ]2 can be obtained by electrocrystallization ]. The crystal is composed one-dimensional TPP arrays surrounded slipped-stacked [Co(Pc)(CN)2 ] chains. electrical conductivity at room temperature quite high, 120 Ω–1 cm–1 , though low it weakly semiconducting. band width for this stacking mode has been estimated from both thermoelectric power measurements and an extended Hückel calculation. latter suggests that the value...

10.1039/a800123e article EN Journal of Materials Chemistry 1998-01-01

Incorporation reactions of carbon dioxide (CO2) with N-Boc-α-amido and α-acetoxy stannanes were developed using CsF as a mild tin activator. Monoprotected α-amido could be used, the corresponding arylglycine derivatives obtained in moderate-to-high yields under 1 MPa (10 atm) CO2 pressure. α-Acetoxy also underwent carboxylation to afford mandelic acid excellent ambient Both transformations enabled synthesis α-tertiary α-quaternary carboxylic derivatives. In addition, chirality...

10.1021/jo202597p article EN The Journal of Organic Chemistry 2012-01-30

Band gap reduction down to 0.8 eV is observed in tin iodide-based hybrid perovskites as a result of bismuth doping. The band originated because lowering the conduction energies. In spite foreign metal doping, number carriers not affected.

10.1039/c7tc00446j article EN Journal of Materials Chemistry C 2017-01-01

Ti-based binary nitride and ternary films were deposited on cemented carbide by the arc ion plating method investigated microhardness, lattice parameter morphology. Micro-Vickers hardness of TiN, CrN, ZrN was 2000, 1400, 1500 HV, respectively. On other hand, nitrides such as (Ti,Al)N, (TiCr)N, (Ti,Zr)N, (Ti,V)N with identical atomic ratio against Ti generally had higher 3100, 3000, 2400 The parameters both (Ti,Al)N (Ti,Cr)N smaller 4.18 4.19 Å. Futhermore, surface roughness ZrN, (TiAl)N,...

10.1116/1.582296 article EN Journal of Vacuum Science & Technology A Vacuum Surfaces and Films 2000-05-01

Dihydropteridine reductase [EC 1.6.99.7] was purified from bovine liver in 50% yield and crystallized. The physicochemical properties of the enzyme were quite similar to those sheep dihydropteridine reductase. During course purification, however, found be separated into 2 major peaks together with minor by column chromatography on CM-Sephadex, one identified as a binary complex NADH. reductase-NADH also prepared vitro Upon addition quinonoid-dihydropterin complex, NADH oxidized released...

10.1093/oxfordjournals.jbchem.a131432 article EN The Journal of Biochemistry 1977-01-01

Because few previous studies have shown the immunohistochemical localization of tryptophan 5-hydroxylase (TPH) in gastrointestinal tract, we developed a specific antibody against TPH purified from mouse mastocytoma P-815 and stained human rat tracts. The specificity was examined by Western blotting immunohistochemistry brain sections. Human ileum colon specimens, stomach, duodenum, jejunum, with without colchicine treatment were prepared for immunohistochemistry. Immunoelectron microscopic...

10.1002/(sici)1096-9861(19990906)411:4<654::aid-cne9>3.0.co;2-h article EN The Journal of Comparative Neurology 1999-09-06

An organic field-effect transistor was fabricated using an anthracene–tetracyanoquinodimethane (AN–TCNQ) single-crystal charge-transfer (CT) complex as the semiconductor material. The CT showed molecular dynamics related to reorientational motion of AN molecule at room temperature. transfer characteristics drastically changed when temperature decreased from 90 K: n-type → ambipolar-type p-type ambipolar-type. From thermal analysis, AN–TCNQ underwent two phase transitions 120 K. To clarify...

10.1021/acs.chemmater.5b01383 article EN Chemistry of Materials 2015-05-27
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