A5089413985- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive System and Pregnancy
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Sperm and Testicular Function
- Endometriosis Research and Treatment
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Gestational Diabetes Research and Management
- Uterine Myomas and Treatments
- Turkish Urban and Social Issues
- Gestational Trophoblastic Disease Studies
- Sexual Differentiation and Disorders
- Ectopic Pregnancy Diagnosis and Management
- Vitamin D Research Studies
- Pregnancy and Medication Impact
- Hypothalamic control of reproductive hormones
- Gynecological conditions and treatments
- Growth Hormone and Insulin-like Growth Factors
- Ovarian cancer diagnosis and treatment
- Sexual function and dysfunction studies
- Birth, Development, and Health
- Cardiovascular Issues in Pregnancy
- Biomedical Research and Pathophysiology
Bahçeşehir University
2018-2024
Marmara University
2021-2023
Istanbul Eye Hospital
2017-2022
Istanbul Medeniyet University
2018-2022
Kayseri Eğitim ve Araştırma Hastanesi
2021
Medical Park Tarsus Hastanesi
2021
Istanbul Memorial Hospital
2014
Hacettepe University
1994-2002
Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of World Health Organization laboratory manual for examination and processing human semen. Many conditions risk factors have been associated with elevated SDF; therefore, it is important identify population infertile men who might benefit from this test. The purpose study investigate global practices related indications SDF testing, compare relevant professional society guideline recommendations, provide expert...
To investigate the effects of body mass index (BMI) values and 25(OH) vitamin D levels determined by Endocrine Society on serum Anti Mullerian Hormone (AMH) antral follicle count (AFC) in women with polycystic ovary syndrome (PCOS).Sixty infertile PCOS 30 age-matched unexplained infertility (UEI), were included. Patients control groups divided into three subgroups according to their BMI as normal, overweight obese. Each group was levels. While AMH at first admission, AFC measured third day...
Abstract Background A fine-tuned pro-inflammatory and anti-inflammatory balance in the follicular unit is essential for cumulus expansion successful ovulation. While long pentraxin 3 (PTX3) gene required of cells (CCs), ovulation, resumption meiosis fertilization, vitamin D receptor (VDR-X2) intra-follicle redox balance. This study was planned to determine expression pattern VDR-X2 PTX3 mRNA CCs isolated from germinal vesicle (GV), metaphase I (MI), II (MII) oocytes PCOS patients with...
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. It characterized by combination hormonal imbalances, ovarian dysfunction, and metabolic disturbances. PCOS has significant implications for women's health, fertility, overall well-being. This comprehensive review aims to provide an overview PCOS, including its etiology, clinical manifestations, diagnosis, management strategies.
The aim of the study was to investigate relationship between serum level vitamin D, semen analysis parameters and sperm DNA damage in men with unexplained subfertility.Fifty-eight diagnosed infertility 50 age BMI matched fertile were included study. A participant whose parameter is normal but pregnancy not achieved accepted as male infertility. Blood samples taken from all participants following three-day abstinence for measurement D. Sperm assessed by Aniline Blue staining collected...
Non-obstructive azoospermia (NOA) is a common, but complex problem, with multiple therapeutic options and lack of clear guidelines. Hence, there considerable controversy marked variation in the management NOA. This survey evaluates contemporary global practices related to medical surgical for patients A 56-question online covering various aspects evaluation NOA was sent specialists around globe. paper analyzes results second half dealing Results have been compared current guidelines, expert...
To investigate the impact of laparoscopic ovarian drilling (LOD) on expression endometrial NFκB p65 (Rel A) in women with clomiphene-resistant polycystic ovary syndrome (PCOS).The study group comprised 25 normal-weight PCOS undergoing LOD and 14 control without PCOS. Endometrial NF-κB levels evaluated before after following immunohistochemical staining. The semiquantitative method was used to evaluate intensity levels. found higher endometrium patients compared controls. leads significant...
To investigate the changes in serum ghrelin and leptin levels patients with clomiphene-resistant polycystic ovary syndrome (PCOS).Thirty-five who could not achieve ovulation or pregnancy despite using 150 mg/day of clomiphene citrate (CC) participated study. Thirty-five were compatible study group terms age body mass index (BMI) but did have clinical laboratory findings PCOS constituted control group. On third day cycle, addition to basal hormone profile, also measured. Patients both groups...
Pruritic urticarial papules and plaques of pregnancy development may have a strong relationship with hormone treatments during in vitro fertilization hormonal changes pregnancy. The aim this study was to evaluate compare the frequency related factors pregnancies spontaneous pregnancies. In study, 517 1253 were retrospectively reviewed for frequency. diagnosis performed by referral dermatology department according typical clinical manifestations disease. more common all (including single...
Objective: To review the outcomes of in vitro maturation (IVM) and fertilization (IVF) women with empty follicle syndrome (EFS).The study evaluated genetic underpinnings EFS by analyzing mutations. Materials Methods:This retrospective case series involving 17 over at least 2 IVF cycles was conducted.The also employed whole-exome sequencing to analyze mutations.The treatment approaches included letrozole-primed IVM, follicle-stimulating hormone (FSH)human chorionic gonadotrophin (hCG)-primed...
Aim: The purpose of this study was to predict the number oocytes using anti-Mullerian hormone (AMH) and Follicle Stimulating Hormone (FSH) levels in In Vitro Fertilization (IVF) candidates. Methods: This retrospective cohort included 121 (23 cases with poor response, 92 normal 6 excessive response) infertile patients. We examined relationship between AMH FSH oocytes. method used consider as response variable identify effective factors. All analyses were performed free R software. Results:...
To investigate whether prior endometrium spectroscopy predicts the success of embryo transfer in patients with recurrent implantation failure (RIF).Twenty women RIF who were scheduled for IVF-ET and six fertile included study. All controls underwent before transfer. A multi-voxel sequence was used detection choline (Cho), creatine (Cr), lactate, lipids. Women divided into two subgroups as successful (n = 8) unsuccessful 12) according to both Cho Cr metabolite characteristics pregnancy...
Autoimmune thyroid diseases are multifaceted conditions in which the gland is infiltrated by lymphocytes, resulting production of thyroid-specific auto-antibodies against peroxidase (TPOAb) and thyroglobulin (TGAb). Iron deficiency a common nutritional has multiple adverse effects on metabolism. The association between iron status autoimmunity not been well-evaluated. This retrospective study aimed to determine whether frequency was higher patients with than healthy individuals negative...
To investigate whether serum levels of estradiol affect reproductive outcomes normoresponder women undergoing fresh embryo transfer (ET) versus frozen-thawed ET (FET).Two hundred fifty-five underwent in their first or second vitro fertilization cycle. Ninety-two with negative pregnacy test results FET. Clinical and ongoing pregnancy rates, implantation, live birth rates FET were compared.One forty-seven (57.65%) out the 255 receiving had positive beta-human chorionic gonadotrophin (hCG)...
To investigate the relationship between thyroid autoimmunity and early pregnancy serum β-HCG levels in intracytoplasmic sperm injection patients.The study subjects were 85 female euthyroid patients undergoing embryo transfer cycles with GnRH antagonist treatment. Patients who received of more than one embryo, those TSH greater 2.5 IU/ml using levothyroxine excluded. Normal responder under age 40 years randomly selected from patient files retrospectively. Subjects divided into two groups:...
Our aim in this study is to evaluate the efficacy of HbA1c screening for GDM during first trimester pregnancy.In retrospective cohort study, we evaluated (ft-HbA1c) levels 195 pregnant women who attended our university hospital's obstetrics clinic. Blood samples were drawn from patients 11-14 weeks gestation. After that, all screened using standardized one-step 75gr OGTT between 24 and 28 included. Thirty-two (16.4%) included diagnosed with GDM. The mean ft-HbA1c level was 5.52% those...
The aim of this study was to compare the complication rates oocyte pick-up (OPU) procedures via transvaginal ultrasonography in patients with different levels ovarian reserve.In total, 789 who underwent OPU for vitro fertilization (IVF) were included study.Individuals normal reserve had a 2.947-fold higher risk complications than individuals low reserve, and high 7.448-fold reserve. In addition, number IVF trials associated an increased complications.The results show that has complications,...
Objective: To determine and compare metabolite content using magnetic resonance spectroscopy (MRS) of growing follicles in patients with polycystic ovary syndrome (PCOS) receiving recombinant follicle stimulating hormone (rFSH), clomiphene citrate (CC) or aromatase inhibitor (AI) for ovarian stimulation. Material Methods:Thirty diagnosed PCOS infertility scheduled stimulation were divided by therapy, rFSH/CC/AI, into three equal groups.Five fertile cases designated as the control group.When...
Aim: Many women of reproductive age who use contraceptive methods have sexual dysfunction and reduced quality life. This study aimed to evaluate the effects various on female function index (FSFI) life scale (SF-12). Methods: prospective observational was conducted patients admitted Gynecology Obstetrics outpatient clinic between August October 2020. FSFI total score sub-domains (desire, arousal, lubrication, orgasm, satisfaction, pain) SF- 12 were used compare differences groups using...