The aim of this study was to report the five scales comprising rating system that Japanese Society for Surgery Foot (JSSF) devised (JSSF standard system) and newly offered interpretations criteria determinations each assessment item. We produced new JSSF by modifying clinical systems established American Orthopaedic Ankle (AOFAS scales) Association's foot scale (JOA scale). also provided item in system. improved ambiguous expressions content conventional so they would be easily understood...

This study evaluated the validity and inter- intraclinician reliability of (1) Japanese Society Surgery Foot (JSSF) standard rating system for four sites [ankle- hindfoot (AH), midfoot (MF), hallux (HL), lesser toe (LT)] rheumatoid arthritis (RA) foot ankle scale (2) Orthopaedic Association’s (JOA scale). Clinicians from same institute independently participating patients their by two evaluations at a 1- to 4-week interval. Statistical evaluation was as follows. The intraclass correlation...

Abstract Objective To analyze the differences in gene expression profiles of chondrocytes intact and damaged regions cartilage from same knee joint patients with osteoarthritis (OA) knee. Methods We compared messenger RNA (classified according to Mankin scale) obtained OA. Five pairs OA were evaluated by oligonucleotide array analysis using a double vitro transcription amplification technique. The microarray data confirmed real‐time quantitative polymerase chain reaction (PCR) previously...

Prostaglandin E synthase (PGES) including isoenzymes of membrane-associated PGES (mPGES)-1, mPGES-2, and cytosolic (cPGES) is the recently identified terminal enzyme arachidonic acid cascade. converts prostaglandin (PG)H2 to PGE2 downstream cyclooxygenase (COX). We investigated expression isoenzyme in articular chondrocytes from patients with osteoarthritis (OA). Chondrocytes were treated various cytokines mRNA was analyzed by reverse transcription–polymerase chain reaction Northern...

To evaluate the involvement of chemokine/chemokine receptor system in cartilage degradation osteoarthritis (OA).Expression 4 C-C chemokines monocyte chemoattractant protein 1 (MCP-1), macrophage inflammatory 1alpha (MIP-1alpha), MIP-1beta, and RANTES, their receptors CCR-2 CCR-5, was assessed 11 OA patients 5 normal controls, by reverse transcriptase-polymerase chain reaction (RT-PCR), enzyme-linked immunosorbent assay (ELISA), immunochemistry, flow cytometry on untreated or...

Background: Few prospective epidemiological studies on soccer match injuries have collected continuous data using subjects from the same group. Purpose: To investigate long-term injury-induced changes during official matches in professional Japanese league. Study Design: Descriptive study. Methods: Acute among top-division leaguers were prospectively 1993 to 2007. Injuries preventing player participation for 7 days or more defined as a reportable injury. Interseasonal variations of injury...

To present time, scientific knowledge about symptoms of common mental disorders and adverse health behaviours among professional soccer players is lacking. Consequently, the aim study was to determine prevalence (distress, anxiety/depression, sleep disturbance) (adverse alcohol behaviour, smoking, nutrition behaviour) players, explore their associations with potential stressors (severe injury, surgery, life events career dissatisfaction). Cross-sectional analyses were conducted on baseline...

To explore the associations of severe musculoskeletal injuries (joint and muscles) surgeries with symptoms common mental disorders (distress, anxiety/depression, sleeping disturbance, adverse alcohol behaviour , smoking, nutrition behaviour) among male European professional footballers.Cross-sectional analyses were conducted on electronic questionnaires completed by footballers recruited from national players' unions Finland, France, Norway, Spain or Sweden. The number (time loss more than...

Objective: Recent reports suggest that exposure to repetitive concussions in sports is associated with an increased risk of symptoms distress, anxiety and depression, sleep disturbance or substance abuse/dependence (typically referred as common mental disorders[CMD]) later development neurodegenerative disease, particular chronic traumatic encephalopathy (CTE). The primary aim this study was explore the relationship between career-related subsequent occurrence CMD among former male...

To determine the 12-month incidence and comorbidity of symptoms common mental disorders (CMD) among European professional footballers to explore association potential stressors with health conditions under study those footballers.Observational prospective cohort a follow-up period 12 months.Male from 5 countries (n = 384 at baseline).Adverse life events, conflicts trainer/coach, career dissatisfaction were explored by using validated questionnaires.Symptoms distress, anxiety/depression,...

Abstract Objective Membrane‐associated prostaglandin E synthase (mPGES) is a recently identified terminal enzyme of the arachidonic acid cascade, which converts PGH 2 to PGE in rheumatoid arthritis synovial fibroblasts (RASFs). This study was undertaken investigate factors regulating expression mPGES. Methods RASFs were treated with interleukin‐1β (IL‐1β), indomethacin, NS‐398, rofecoxib, or meloxicam. The effects and selective agonists for receptor subtypes (EP1, EP2, EP3, EP4) also...

The effects of heat-stress on proliferative potential in vivo were studied rat skeletal muscle. Male Wistar rats (7-weeks-old) divided into two groups: control (n &equals; 24) and heat-stressed 24). Rats the experimental group exposed to environmental (41°C for 60 min) a heat chamber without anesthesia. soleus muscles dissected 1, 7, 14 days after exposure. wet dry weights muscle relative body weight significantly higher than controls 7 exposure (10.1% 17.5%, respectively, p < 0.05)....

Objective: To investigate the incidence of acute injuries and soccer-related chronic pain from long-term training during matches in adolescent players using natural grass turfs (NT) artificial (AT). Design: Case-controlled prospective study. Setting: Institutional-level Fédération Internationale de Football Association Medical Centre Excellence. Participants: Youth soccer (12-17 years age) 6 teams, with a predominant tendency to train on either NT or AT, were included. Of 332 enrolled this...

The aim of the study was twofold, namely (i) to determine prevalence symptoms common mental disorders (CMDs) among current and retired professional football handball players (ii) explore relationship psychosocial stressors with outcome measures under study. A total 1155 were enrolled in an observational based on a cross-sectional design. Questionnaires validated scales set up distributed by Danish players' union. In football, highest (4 weeks) CMDs 18% 19% for anxiety/depression players,...

The primary aim was to establish the association between osteoarthritis (OA) and occurrence comorbidity of symptoms common mental disorders (CMD: distress, anxiety/depression, sleep disturbance, adverse alcohol use) in a group former elite athletes (rugby, football, ice hockey, Gaelic sports cricket). A secondary explore this subgroups sports.Cross-sectional analysis performed on baseline questionnaires from five prospective cohort studies conducted April 2014 January 2016 rugby, cricket....

As a consequence of severe knee injuries, osteoarthritis (OA) seems prevalent in retired professional footballers. However, some epidemiological data remain missing, for instance whether OA is also current footballers, associated with injuries and surgeries, leads to lower level functioning. Therefore, three research questions were answered: (i) what the prevalence among footballers? (ii) injury or surgery (iii) are consequences on physical function footballers?An observational study based...

Mental disorders have become a topic of increasing interest in research due to their serious consequences for quality life and functioning.The objective this study was explore the relationship level education, employment status working hours with symptoms common mental (distress, anxiety/depression, sleep disturbance, adverse alcohol behaviour, smoking, nutritional behaviour) among current retired professional footballers.Cross-sectional analyses were conducted on baseline questionnaires...