A5010422845- Advanced Polymer Synthesis and Characterization
- Surfactants and Colloidal Systems
- Hydrogels: synthesis, properties, applications
- Polymer Surface Interaction Studies
- Block Copolymer Self-Assembly
- Polymer Nanocomposites and Properties
- biodegradable polymer synthesis and properties
- Dendrimers and Hyperbranched Polymers
- Polymer crystallization and properties
- Electrostatics and Colloid Interactions
- Supramolecular Self-Assembly in Materials
- Material Dynamics and Properties
- Nanoparticle-Based Drug Delivery
- Advanced Materials and Mechanics
- 3D Printing in Biomedical Research
- Graphene research and applications
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Rheology and Fluid Dynamics Studies
- Membrane Separation and Gas Transport
- Supramolecular Chemistry and Complexes
- Conducting polymers and applications
- Force Microscopy Techniques and Applications
- Analytical Chemistry and Chromatography
- Synthesis and properties of polymers
University of Patras
2015-2024
Foundation for Research and Technology Hellas
2005-2018
FORTH Institute of Chemical Engineering Sciences
2006-2015
Laboratoire de Mathématiques de Bretagne Atlantique
2006-2009
Clarkson University
2003-2008
University of Cyprus
2005-2007
Iowa State University
2006
Fraunhofer Institute for Applied Polymer Research
2003
University at Buffalo, State University of New York
2001
Lund University
2001
The present review highlights the recent developments on reversible hydrogels which are formed through self-assembling and association mechanisms of well-defined macromolecular entities able to respond external stimuli like temperature, pH, light chemical triggers. Thanks great progress engineering, especially enormous development "living"/controlled polymerization methods, together with ability create artificial peptide-based macromolecules recombinant DNA novel "smart" capable form...
In this work a dual crosslinked network based on sodium alginate graft copolymer, bearing poly(N-isopropylacrylamide-co-N-tert-butylacrylamide) P(NIPAM-co-NtBAM) side chains was developed and examined as shear thinning soft gelating bioink. The copolymer found to undergo two-step gelation mechanism; in the first step three-dimensional (3D) is formed through ionic interactions between negatively ionized carboxylic groups of backbone positive charges Ca2+ divalent cations, according "egg-box"...
A novel liposome/hydrogel soft nanocomposite was explored as a controlled drug delivery system. P2VP-PAA-PnBMA biocompatible, pH-responsive triblock terpolymer used an injectable gelator, entrapping PC/Chol liposomes loaded with calcein hydrophilic model drug. The composite hydrogel formed in vitro through pH-induced sol–gel transition by dialysis against buffer under physiological conditions and at polymer concentration low 1 wt %. Excellent control of the release achieved just adjusting...
Multicompartmental responsive microstructures with the capability for pre-programmed sequential release of multiple target molecules opposite solubility (hydrophobic and hydrophilic) in a controlled manner have been fabricated. Star block copolymers dual-responsive blocks (temperature poly(N-isopropylacrylamide) chains pH poly(acrylic acid) poly(2-vinylpyridine) arms) unimolecular micellar structures serve as nanocarriers hydrophobic microcapsule shell. The interior can be loaded...
Polystyrene (PS) end-capped polyelectrolytes were prepared by modification of polystyrene−poly(tert-butyl acrylate)−polystyrene triblock copolymers synthesized via anionic polymerization. These amphiphilic polymers are associated in dilute aqueous solutions forming loose multimicellar clusters. At higher polymer concentrations an extensive intermicellar bridging occurs, leading to the formation a transient network as revealed viscoelastic response system. The so-formed gel is characterized...
Single molecule conformations and associate morphologies for polystyrene/poly(2-vinylpyridine) (PS7−P2VP7) heteroarm star copolymer, formed in controlled environment deposited onto mica or Si wafers, have been studied by atomic force microscopy (AFM) with molecular resolution. At concentrations below 0.01 mg/mL PS7−P2VP7 exists the molecularly dissolved state both selective (acidic water, toluene) common good (chloroform, tetrahydrofuran) solvents. In acid conditions forms either...
Abstract Hetero‐arm star copolymers are constituted of a central core carrying branches two kinds. The two‐stage synthesis such polymer species involves an arm‐first step and core‐first step: A linear anionic living polystyrene precursor was used to initiate the polymerization small amount divinylbenzene, yielding star‐shaped bearing sites inside cores; in second stage these were another monomer — butyl methacrylate —, more electrophilic than styrene. This results formation new set...
Star shaped segmented macromolecules constitute an interesting class of polymeric materials whose properties differ remarkably from those appearing in their linear counterparts. This review highlights the work done last decade, dealing with self-assembly star-shaped block copolymers and terpolymers various topologies aqueous media. article focuses on a specific star designated as stimuli responsive. These stars bearblock/arms undergo sharp phase transitions upon responding to stimuli, such...
A novel thermoresponsive gelator of (B-co-C)-b-A-b-(B-co-C) topology, comprising a poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) weak polyelectrolyte as central block, end-capped by thermosensitive poly(triethylene glycol methyl ether methacrylate/n-butyl [P(TEGMA-co-nBuMA)] random copolymers, was designed and explored in aqueous media. The main target this design to control the dynamics stickers temperature create an injectable hydrogel that behaves gel at low strong physiological...
Polysaccharide-based graft copolymers bearing thermo-responsive grafting chains, exhibiting LCST, have been designed to afford injectable hydrogels. The good performance of the hydrogel requires control critical gelation temperature, Tgel. In present article, we wish show an alternative method tune Tgel using alginate-based gelator two kinds chains (heterograft copolymer topology) P(NIPAM86-co-NtBAM14) random and pure PNIPAM, differing in their lower solution temperature (LCST) about 10 °C....
Abstract Soft materials are usually defined as made of mesoscopic entities, often self-organised, sensitive to thermal fluctuations and weak perturbations. Archetypal examples colloids, polymers, amphiphiles, liquid crystals, foams. The importance soft in everyday commodity products, well technological applications, is enormous, controlling or improving their properties the focus many efforts. From a fundamental perspective, possibility manipulating material properties, by tuning...
Unimolecular micelles constituted from the star-shaped PS7−P2VP7 polysterene/poly(2-vinylpyridine) block copolymer single molecules were studied with molecular resolution using AFM. In selective solvent unimers show core−shell structures very pronounced segregation into collapsed core and extended shell formed by stretched polymer arms of P2VP PS in water toluene, respectively. Metallization leads to organic−inorganic nanocomposite 1−3 nm diameter palladium clusters localized outer unimers,...
A heteroarm star block copolymer made from seven polystyrene and poly(2-vinylpyridine) arms was grafted onto a solid substrate to fabricate responsive polymer surface consisting of densely packed monolayer molecules. The layer demonstrates two-level hierarchical response upon external stimuli combining core−shell transitions single stars with cooperative the interacting between "dimple" "ripple" morphologies monolayer. allows for switching properties changing solvent selectivity or pH...
We report on the viscoelastic response of a physical gel formed in aqueous solutions poly(sodium acrylate) end-capped with short polystyrene (PS) blocks. Above percolation threshold (cgel = 0.2 wt %) transient network is constituted PS hydrophobic domains (cross-links) interconnected via fully charged polyelctrolyte chains. Oscillatory shear and step-strain experiments were employed to study properties. The stretched conformation middle blocks (bridges) high hydrophobicity ends have...
We report on the phase behavior and micellization phenomena of a poly(2-vinylpyridine-b-poly(methyl methacrylate)-b-(poly(acrylic acid) block terpolymer (P2VP−PMMA−PAA) in aqueous dilute solutions. This double hydrophilic exhibits different self-assemblies depending pH solution. At low (1−2) heteroarm starlike micelles are formed bearing interactive P2VP PAA arms corona. Aging due to intramicelleral interactions lead morphology changes from Janus (segregated arms) shell cross-linked (mixed...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCore-first synthesis of star polymers with potentially ionogenic branchesConstantinos Tsitsilianis, Pierre Lutz, Sabine Graff, Jean Philippe Lamps, and Paul RemppCite this: Macromolecules 1991, 24, 22, 5897–5902Publication Date (Print):October 1, 1991Publication History Published online1 May 2002Published inissue 1 October 1991https://pubs.acs.org/doi/10.1021/ma00022a001https://doi.org/10.1021/ma00022a001research-articleACS PublicationsRequest...
We report on the association capability of a novel multisegmented, multiarm star terpolymer to form diversity pH-responsive amphoteric micellar nanostructured self-assemblies.
This article is dealing with the design of novel segmented polymers comprising homopolymer and random copolymer building blocks designated as block-random. type polymeric materials can be prepared through macromolecular engineering by using controlled polymerization methods. By replacing a block one, in topologies, further tuning properties achieved. The present highlights recent developments on block-random macromolecules, bearing tunable (e.g. thermo-sensitivity (LCST), hydrophobicity)...