A5111944176- Vector-borne infectious diseases
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Rabies epidemiology and control
- Yersinia bacterium, plague, ectoparasites research
- Pneumocystis jirovecii pneumonia detection and treatment
- Helminth infection and control
- Dermatological diseases and infestations
- Bacteriophages and microbial interactions
- Bartonella species infections research
- RNA modifications and cancer
- Parasites and Host Interactions
- Respiratory viral infections research
- Frailty in Older Adults
- Oral microbiology and periodontitis research
- Insect and Pesticide Research
- Mosquito-borne diseases and control
- Syphilis Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Infectious Diseases and Tuberculosis
- Oral and gingival health research
Peruvian University of Applied Sciences
2025
Universidad Centroamericana José Simeón Cañas
2024
Hospital San Pedro
2006-2023
Center for Biomedical Research of La Rioja
2007-2022
Hospital Universitario Reina Sofía
2018
Universidad Nacional Autónoma de México
2008
Centro de Alta Resolución San Millán
2007
Hospital General de La Rioja
2000-2006
In-Q-Tel
2003
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2003
Abstract We identified Rickettsia monacensis as a cause of acute tickborne rickettsiosis in 2 humans. Its pathogenic role was assessed by culture and detection the organism patients’ blood samples. This finding increases number recognized human rickettsial pathogens expands known geographic distribution Mediterranean spotted fever–like cases.
ABSTRACT The first cluster of cases human Rickettsia felis infection in Spain diagnosed by PCR is reported.
Abstract: This study describes the epidemiological, clinical, and microbiological characteristics of a new tick‐borne disease in Spain— Dermacentor‐ borne necrosis erythema lymphadenopathy (DEBONEL). The clinical presentations include an eschar at site tick bite, surrounded by painful regional lymphadenopathy. appears during colder months its vector is Dermacentor marginatus (D. marginatus). From January 1990 to December 2004, 54 patients presented Hospital La Rioja with these...
Human immunodeficiency virus (HIV) infection can be considered a chronic disease thanks to the extended use of antiretroviral treatment (ART). In this context, low-grade inflammation related gut microbiota (GM) dysbiosis and bacterial translocation (BT) among other factors has been observed despite ART. addition, different ART regimens have demonstrated differential impacts on GM. However, role novel integrase strand transfer inhibitors (INSTIs) not investigated yet. The aim study was...
Background Patients with HIV infection suffer from accelerated aging. In this context, frailty could be a relevant problem that aggravates the quality of life (QoL) and morbi-mortality these patients. Our objective was to determine prevalence pre-frailty in HIV-infected patients our cohort as well their risk factors QoL. Methods This prospective cross-sectional study people aged ≥18 years on stable antiretroviral regimen (ART) ≥1 year. Frailty defined by ≥3 5 Fried's criteria: weight loss,...
During recent decades, a tick-borne rickettsial syndrome, characterized by eschar and painful lymphadenopathy after Dermacentor marginatus-bite, has been described as an emerging rickettsiosis in Europe. Our group named it DEBONEL (Dermacentor-borne-necrosis-erythema-lymphadenopathy), regarding the vector main infection signs. Other groups called TIBOLA (tick-borne-lymphadenophathy) and, later, SENLAT (scalp-eschar-and-neck-lymphadenopathy-after-tick-bite), expanding, latter, etiological...
Abstract Viruses are the most abundant components of human gut microbiome with a significant impact on health and disease. The effects immunodeficiency virus (HIV) infection virome has been scarcely analysed. Several studies suggested that integrase strand transfers inhibitors (INSTIs) associated healthier gut. Thus, objective this work was to evaluate HIV INSTIs composition. 26 non-HIV-infected volunteers, 15 naive HIV-infected patients INSTIs-treated were recruited their composition...
In the course of characterizing 103 rotaviruses from children in Mexico, we found that majority strains were globally common types (55.4% total), while uncommon represented 5.7%, mixed infections with 14.8%, and partially or fully nontypeable isolates about 24%. Serotype G9 was detected for first time Mexico. We sequenced a subset G by reverse transcriptase PCR surprisingly two having human rotavirus P genotypes (8 6) had serotype G3 G4 VP7 gene sequences shared closer homology canine...
A total of 53 engorged adult ticks belonging to the species Rhipicephalus (Boophilus) decoloratus (N = 9), evertsi 27), appendiculatus Amblyomma hebraeum 5), and Hyalomma marginatum turanicum 3), were removed from oryx in Botswana (South Africa). They tested for presence spotted fever group (SFG) Rickettsia Anaplasma phagocytophilum using polymerase chain reaction (PCR). Seventy-seven percent R. as well twenty A. positive ompA, gltA 16S rRNA SFG PCR assays. All nucleotide sequences...
Abstract: Our objective was to learn the prevalence of spotted fever group (SFG) Rickettsia detected in ticks La Rioja, north Spain. From 2001 2005, 496 representing 7 tick species were analysed at Hospital de Rioja. Ticks removed from humans with or without rickettsial syndrome ( n = 59) collected mammals 371) vegetation by dragging 66). The presence SFG these investigated semi‐nested PCR ompA gene) and sequencing. A phylogenetic tree using Clustal method (neighbor‐joining) constructed...
Abstract: In southern Spain, Dermacentor marginatus ticks can be infected with several genospecies of spotted fever Group (SFG) Rickettsia . We developed a nested polymerase chain reaction assay by using species‐specific probe targeting the ompA gene to detect and differentiate between two groups rickettsiae previously described in D. SFG rickettsia has been detected 85.15% studied (26.7% positives have R. slovaca , causative agent TIBOLA‐DEBONEL, 73.3% closely related strains...
A bstract : Our aim was to identify variants of Anaplasma phagocytophilum 16S rRNA gene sequences among products amplified from Ixodes ricinus collected in La Rioja, Spain. A. AP‐variant 1, reported as non‐pathogenic, detected 12 samples (two adults and ten nymphs). This finding could justify the low incidence human anaplasmosis our area, despite high prevalence ticks.