A5045136308- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Trauma and Emergency Care Studies
- Injury Epidemiology and Prevention
- Heavy Metal Exposure and Toxicity
- Nutritional Studies and Diet
- Dialysis and Renal Disease Management
- Cardiac Arrest and Resuscitation
- Vitamin D Research Studies
- Diet, Metabolism, and Disease
- Healthcare Systems and Reforms
- Automotive and Human Injury Biomechanics
- Opioid Use Disorder Treatment
- Air Quality and Health Impacts
- Global Health and Epidemiology
- Renal Transplantation Outcomes and Treatments
- Bone health and osteoporosis research
- Emergency and Acute Care Studies
- Obesity, Physical Activity, Diet
- Cardiac and Coronary Surgery Techniques
- Cardiac pacing and defibrillation studies
- Healthcare cost, quality, practices
University of Leicester
2025
University of Ottawa
2023
NIHR Leeds Musculoskeletal Biomedical Research Unit
2023
Brigham and Women's Hospital
2016-2019
Harvard University
2014-2019
Emory University
2012-2019
Boehringer Ingelheim (United States)
2019
STATinMED (United States)
2019
Tufts Medical Center
2019
Georgia Department of Public Health
2015
In the current health care environment with increased scrutiny and growing concern regarding opioid use abuse, there has been a push toward greater regulation over prescriptions of opioids. Trauma patients represent population that may be affected by this regulation, as incidence pain at hospital discharge is than 95%, opioids are considered first line treatment for management. However, in trauma not explored.To study predictors prescription large national cohort.Analysis adult (18-64...
Abstract Introduction: In a populous city like Mumbai, which lacks an organized pre-hospital emergency medical services (EMS) system, there exists informal network through victims arrive at the trauma center. This baseline study describes prehospital care and transportation that currently is available in Mumbai. Methods: A prospective database was created by interviewing 170 randomly selected patients from total of 454 admitted over two-month period (July–August 2005) Level-I, urban,...
Summary Objective Redox status and inflammation are important in the pathophysiology of numerous chronic diseases. Epidemiological studies have linked vitamin D to a number We aimed examine relationships between serum 25‐hydroxyvitamin [25( OH )D] circulating thiol/disulphide redox biomarkers inflammation. Design This was cross‐sectional study N = 693 adults (449 females, 244 males) an apparently healthy, working cohort Atlanta, GA . Plasma glutathione ( GSH ), cysteine (Cys) their...
Supplemental melatonin may ameliorate metabolic syndrome (MetS) components, but data from placebo-controlled trials are lacking.We conducted a double-blind, placebo-controlled, crossover, Phase II randomized pilot clinical trial to estimate the effects of supplementation on MetS components and overall prevalence MetS. We 39 subjects with receive 8.0 mg oral or matching placebo nightly for 10 weeks. After 6-week washout, received other treatment more measured waist circumference,...
Atherosclerotic changes associated with dyslipidemia and increased cardiovascular disease risk are believed to begin in childhood. While previous studies have linked added sugars consumption low high-density lipoprotein (HDL), little is known about the long-term impact of this consumption. This study aims assess association between intake HDL cholesterol levels during adolescence, whether modified by obesity.
Background Cardiometabolic diseases are a major cause of morbidity and mortality in kidney transplant recipients (KTR) due to clustering traditional non-traditional risk factors including poor physical fitness inactivity. Exercise may mitigate the these this population but evidence is limited, activity levels low. The ECSERT randomised controlled trial assessed feasibility delivering structured, home-based exercise intervention KTR at increased cardiometabolic risk. Methods Fifty (>1-year...
Geographic variation of pre-end-stage renal disease (pre-ESRD) nephrology care has not been studied across the United States. Here we sought to identify geographic differences in pre-ESRD care, assess for county-level and sociodemographic risk factors, correlate with patient outcomes using facility-level mortality. Patients from 5387 dialysis facilities States 2007 2010 were included Dialysis Facility Report. Marginal generalized estimating equations used modeling cluster analysis detect...
Objective The aim of this study was to determine if the association with adiposity varies by type (added vs. naturally occurring) and form (liquid solid) dietary sugars consumed. Methods Data from 10-year National Heart, Lung, Blood Institute (NHLBI) Growth Health Study (n = 2,021 girls aged 9–10 years at baseline; n 5,156 paired observations) were used. Using mixed linear models, 1-year changes in sugar intake, body mass index z-score (BMIz) waist circumference (WC) assessed. Results...
Doctors considering strike action may worry about the effect on patients. David Metcalfe and colleagues examine evidence
Contemporary options for aortic valve replacement (AVR) include transcatheter and surgical approaches (TAVR SAVR). As evidence accrues TAVR in high intermediate risk patients, some clinicians advocate that all patients aged over 80 years should only receive TAVR. Our aim was to investigate the utility of SAVR minimally invasive AVR (mAVR) among octogenarians current era TAVR.From 2002 2015, 1,028 underwent isolated AVR; 306 722 SAVR, which 378 mAVR. Logistic regression Cox modeling were used...
Background : Pancreatic insufficiency is common in patients with cystic fibrosis (CF) and leads to malabsorption of fat‐soluble vitamins. Multivitamins, including vitamins A, D, E, K, are routinely prescribed CF prevent vitamin deficiencies. Our objective was examine the relationship between supplements their impact on blood concentrations. Methods This a retrospective chart review who were treated at Emory Clinic University Hospital during 2008–2012. The amount supplementation, serum...
Patient preferences are assumed to impact healthcare resource utilization, especially treatment options. There is limited data exploring this phenomenon. We sought identify factors associated with patients transferring care for prostatectomy, from military civilian facilities, and the receipt of minimally invasive radical prostatectomy (MIRP).Retrospective review 2006-2010 TRICARE identified men diagnosed prostate cancer (ICD-9 185) receiving open (ORP; ICD-9: 60.5) or MIRP 60.5 +...