A5027233892- Glutathione Transferases and Polymorphisms
- Genomics, phytochemicals, and oxidative stress
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- Porphyrin Metabolism and Disorders
- DNA and Nucleic Acid Chemistry
- Drug Transport and Resistance Mechanisms
- Selenium in Biological Systems
- Pharmacogenetics and Drug Metabolism
University of Turku
2011-2016
Åbo Akademi University
2011-2016
Turku Centre for Biotechnology
2011-2016
A library of Tau class GSTs (glutathione transferases) was constructed by DNA shuffling using the encoding Glycine max GmGSTU2-2, GmGSTU4-4 and GmGSTU10-10. The parental are >88% identical at sequence level; however, their specificity varies towards different substrates. contained chimaeric structures alternated segments sequences point mutations. Chimaeric GST were expressed in Escherichia coli enzymatic activities CDNB (1-chloro-2,4-dinitrobenzene) herbicide fluorodifen (4-nitrophenyl...