- Acute Myocardial Infarction Research
- Healthcare Regulation
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Public Health in Brazil
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Health and Mental Health
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Sex and Gender in Healthcare
- Healthcare during COVID-19 Pandemic
- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- Estrogen and related hormone effects
- Peripheral Artery Disease Management
- Cardiac pacing and defibrillation studies
- Aortic aneurysm repair treatments
- Tracheal and airway disorders
- Biomedical and Engineering Education
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Arrhythmias and Treatments
- Health, Nursing, Elderly Care
- Antifungal resistance and susceptibility
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2016-2025
Universidade de São Paulo
2015-2025
Instituto do Coração
2016-2021
Universidad Surcolombiana
2020
Weatherford College
2020
Hospital Universitário da Universidade de São Paulo
2019
Université de Montpellier
2017
Institut de Génétique Moléculaire de Montpellier
2017
Hospital TotalCor
2016
Cliniques Universitaires Saint-Luc
2010
1. Epidemiologia da Parada Cardiorrespiratoria e Apresentacao Diretriz […] Atualizacao de Ressuscitacao Cardiopulmonar Cuidados Cardiovasculares Emergencia Sociedade Brasileira Cardiologia – 2019
We present the case of a woman admitted for an acute ST-segment elevation myocardial infarction. Emergency catheterization was conducted, revealing diffuse lesions affecting 70% anterior descending artery from mid to distal third but with ventriculography compatible Takotsubo syndrome. Two magnetic resonances were performed 90 days apart, confirming unusual coexistence syndrome and transmural infarction in same event.
Acute aortic syndromes (AAS) are deadly conditions causing unspecific symptoms, such as chest/abdominal/back pain, syncope and neurological deficit. They diagnosed with computed tomography angiography (CTA), but the patient selection is challenging. To support physicians standardize management, protocols combining a clinical score D-dimer (DD) have been developed. However, direct comparison of their diagnostic performance cost-effectiveness lacking. We used individual data from 3 prospective...
Background: Gender-related differences have been reported in patients with acute coronary syndrome. The description of this comparative finding a Brazilian registry has not yet documented. Objective: To compare male vs. female regarding the baseline characteristics, findings, treatment and in-hospital long-term prognosis. Methods: This is retrospective, multicenter observational study that included 3,745 (2,437 males 1,308 females) between May 2010 2015. primary outcome was all-cause...
Background: Some small studies have related higher levels of thyrotropin (TSH) to potentially worse prognosis in acute coronary syndromes. However, this relationship remains uncertain. Objective: To analyze the outcomes patients with syndromes relation value TSH at admission. Methods: Observational and retrospective study 505 (446 group I [TSH ≤ 4 mIU/L] 59 II > mIU/L]) between May 2010 2014. We obtained data about comorbidities medications used hospital. The primary endpoint was in-hospital...
Background: Recent studies have shown fondaparinux's superiority over enoxaparin in patients with non-ST elevation acute coronary syndrome (ACS), especially relation to bleeding reduction. The description of this finding a Brazilian registry has not yet been documented. Objective: To compare fondaparinux versus in-hospital prognosis ACS. Methods: Multicenter retrospective observational study. A total 2,282 were included (335 the group, and 1,947 group) between May 2010 2015. Demographic,...
OBJECTIVES: Recent studies have revealed a relationship between beta-blocker use and worse prognosis in acute coronary syndrome, mainly due to higher incidence of cardiogenic shock.However, the relevance this reperfusion era is unknown.The aim study was analyze outcomes patients with syndrome that started oral beta-blockers within first 24 hours hospital admission (group I) compared who did not timeframe II).METHODS: This an observational, retrospective multicentric 2,553 (2,212 group I 341...
1. Introducao A pandemia pelo novo coronavirus (SARS-CoV-2) vem gerando debates a respeito do melhor tratamento para doenca e suas complicacoes. Publicacoes recentes demonstraram que as doencas cardiovasculares (DCV) estao entre os principais fatores de risco evolucao desfavoravel da doenca, incluindo hipertensao arterial diabetes mellitus. – Foi demonstrado pacientes com infeccao (COVID-19) apresentam mecanismos pro-tromboticos distintamente ativados, maior possibilidade eventos tromboticos...
Oral estrogens improve endothelial function, and for this reason may be considered cardioprotective; however, in women with coronary heart disease there also an increase the risk of thrombosis. Although transdermal estrogen administration decrease adverse effect, are few data on function treated using such therapy. This study aimed to report response postmenopausal estrogen.This was a double-blind, prospective, randomized study. Eighteen patients history acute syndrome nine healthy were...
Summary The inflammation of aortic wall, named aortitis, is a rare condition that can be caused by number pathologies, mainly inflammatory or infectious in nature. In this context, the occurrence combined audiovestibular and/or ocular manifestations eventually led to diagnosis Cogan's syndrome, making it case, but susceptible adequate immunosuppressive treatment and satisfactory disease control.
In Chile, 40% of deaths due to acute myocardial infarction occur in women.To assess the presence cardiovascular risk factors women with coronary syndromes.Thirty four aged 46 55 years old, admitted hospital an syndrome and 102 age matched healthy were studied. A clinical history was obtained, blood pressure fasting serum lipids measured.A high present 65 16% patients controls respectively. Seventy seven percent 36% smoked, 76% 48% postmenopausal, 21% 5% diabetic. respectively total...
Introduction: Despite having higher sensitivity as compared to conventional troponins, sensitive troponins have lower specificity, mainly in patients with renal failure. Objective: Study aimed at assessing the troponin I levels chest pain, and relating them existence of significant coronary lesions. Methods: Retrospective, single-center, observational. This study included 991 divided into two groups: (N = 681) without 310) lesion. For posterior analysis, were other 184) 807) chronic The...
SUMMARY Cardiac myxoma is a benign neoplasm, which corresponds to the most common primary heart tumour, responsible for about 50% of cases. In general, 75-80% myxomas are located in left atrium, 18% right and more rarely ventricles or multicentric. Right atrial myxoma, particular, can obstruct tricuspid valve, causing symptoms failure, peripheral oedema, hepatic congestion, syncope. Systemic embolization occurs 30% cases, by either tumour fragmentation total detachment. present report, we...
Background: There is limited evidence in the literature regarding administration of clopidogrel to acute coronary syndrome (ACS) patients over 75 years age. Most studies excluded this age group, making subject controversial due increased risk bleeding population. Objective: This a retrospective, unicentric, and observational study aimed at assessing whether loading dose increases rates Methods: Patients were divided into two groups: group I: mg clopidogrel; II: 300-to 600-mg clopidogrel. A...
Abstract Rationale: Systemic embolism is a known complication of infective endocarditis (IE), but it rarely presents as acute myocardial infarction (AMI). Aspiration thrombectomy without stenting possible approach in this context. The authors present rare case coronary caused by Aggregatibacter aphrophilus IE successfully treated with manual aspiration thrombectomy. Patient concerns: A 19-year-old man previous valve disease was admitted to the emergency department fever and dyspnea. next...
Purpose: To compare the demographic data and outcomes of younger versus elderly patients with acute coronary syndromes. Methods: This was a retrospective bank analysis study 966 (268 in group (less than 55 years) 698 (more years)). Data were obtained about clinical characteristics, angiography, medication used at hospital definitive treatment. The primary endpoint all cause in-hospital death combined events. Comparison between groups made by Anova Q-square. Multivariative determined logistic...
Objective: The objective of this study was to analyse the reversibility anticoagulant effect warfarin by comparing prothrombin complex concentrate (PCC) versus frozen fresh plasma (FFP) in cardiology patients with serious intoxication. Methods: This an observational and retrospective comprising 67 (18 group I [PCC] 49 II [FFP]). primary endpoint reversal after 2 24 hours PCC or FFP administration. Comparisons between groups were made using T-test Q-square. Multivariate analyses conducted...
Objective: Oral estrogens improve endothelial function, and for this reason may be considered cardioprotective; however, in women with coronary heart disease there also an increase the risk of thrombosis. Although transdermal estrogen administration decrease adverse effect, are few data on function treated using such therapy. This study aimed to report response postmenopausal estrogen. Materials methods: was a double-blind, prospective, randomized study. Eighteen patients history acute...
The pharmacokinetics (PK) of isepamicin were studied in 8 febrile neutropenic patients with hematologic malignancy and 20 young women acute pelvic inflammatory disease (PID). Isepamicin was given as a slow intravenous infusion over 30 min at dose 15 mg/kg once daily (OD). Serum levels determined by fluorescence polarization immunoassay, PK analyses obtained based on one-compartment open model after 24 hours (steady state) 7 days.On day 1, the volume distribution (Vd) isepamicin, for both...