A5061221283- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Respiratory viral infections research
- Blood Pressure and Hypertension Studies
- Radiomics and Machine Learning in Medical Imaging
- Congenital Heart Disease Studies
- Infection Control in Healthcare
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Bacterial Identification and Susceptibility Testing
- Enterobacteriaceae and Cronobacter Research
- Infection Control and Ventilation
- Infective Endocarditis Diagnosis and Management
- Cardiac tumors and thrombi
- Enhanced Recovery After Surgery
- Antiplatelet Therapy and Cardiovascular Diseases
- Platelet Disorders and Treatments
- Food Safety and Hygiene
- Cardiac and Coronary Surgery Techniques
- Sarcoma Diagnosis and Treatment
Rigshospitalet
2008-2025
Copenhagen University Hospital
2013-2020
Icahn School of Medicine at Mount Sinai
2014
University of Copenhagen
2013
Slagelse Hospital
2007
Use of 80% oxygen during surgery has been suggested to reduce the risk surgical wound infections, but this effect not consistently identified. The on pulmonary complications well defined.To assess whether use reduces frequency site infection without increasing in patients undergoing abdominal surgery.The PROXI trial, a patient- and observer-blinded randomized clinical trial conducted 14 Danish hospitals between October 2006 2008 among 1400 acute or elective laparotomy.Patients were randomly...
Early mobilization is important for postoperative recovery but limited by orthostatic intolerance (OI) with a prevalence of 50% 6 h after major surgery. The pathophysiology OI assumed to include hypovolemia besides dysregulation vasomotor tone. Stroke volume-guided fluid therapy, so-called goal-directed therapy (GDT), corrects functional hypovolemia, and the authors hypothesized that GDT reduces surgery assessed this in prospective, double-blinded trial.Forty-two patients scheduled open...
Background/Objectives: The complexity of Minimally Invasive Mitral Valve Surgery (MIMVS) could cause a slow learning curve and potentially patient harm. We thus investigated if novice mitral valve center encountered difficulties implementing MIMVS. Methods: seven hundred forty-eight surgery patients, two years before after MIMVS introduction. Results: propensity score matched sixty elective patients for comparison, with one thirty in each group. Surgical- (5.5 vs. 4.3 h), Cardiopulmonary...
Background/Objectives: To investigate if mitral valve centers encounter challenges implementing Minimally Invasive Mitral Valve Surgery (MIMVS). Methods: We investigated surgery patients, before and after MIMVS introduction. Results: propensity score matched two hundred sixty elective patients for comparison. Surgical- (5.5 vs 4.3h), CPB- (180 102 min) aortic cross-clamp times (98 vs. 81 became longer One year mortality in-hospital outcomes remained unaffected. Hospital length of stay...
Describe changes in measures of right ventricular (RV) function patients treated for aortic stenosis using open-chest surgery (SAVR) or transcatheter treatment (TAVR).Patients the Nordic Aortic Valve Intervention (NOTION) trial were randomized 1:1 to TAVR (n = 114) SAVR 106). Echocardiography was performed at baseline and 3 12 months post-procedure. Tricuspid annular plane systolic excursion (TAPSE) fractional area change (RVFAC) used as longitudinal transverse RV contraction. Left ejection...
Our objective was to evaluate local guidelines regarding early steroid treatment in adult community acquired bacterial meningitis, and assess the actual given its correlation clinical outcome. Patient outcome obtained retrospectively from medical records of 210 adults admitted 47 hospitals Denmark during 2002–2004 (population 5.4 million) combined with results a questionnaire these hospitals. In 36 departments responding questionnaire, 21 recommended treatment, but none did so initially...
Abstract Background Translational molecular imaging using Positron Emission Tomography/Computed Tomography (PET/CT) and Transesophageal Echocardiography (TEE) are powerful non-invasive tools for investigation monitoring of cardiovascular functions. Following myocardial infarction (MI), formation new blood vessels (angiogenesis) is importance in the healing process can be assessed with PET tracer 68Ga-NODAGA-E[(cRGDyK)]2 (68Ga-RGD). Purpose The purpose study was to assess angiogenesis a...