A5050813225- Cardiac tumors and thrombi
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Imaging and Diagnostics
- Peptidase Inhibition and Analysis
- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- Orthopaedic implants and arthroplasty
- Nanoparticle-Based Drug Delivery
- Tissue Engineering and Regenerative Medicine
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Sarcoma Diagnosis and Treatment
Rigshospitalet
2017-2023
Copenhagen University Hospital
2019-2023
University of Copenhagen
2017-2023
The objective of this study was to investigate the effects semaglutide, a long acting glucagon-like peptide-1 receptor agonist, on atherosclerotic inflammation and calcification using multimodality positron emission tomography computed (PET/CT) approach.Atherosclerotic New Zealand White rabbits were randomized an intervention- (n = 12) or placebo group 11) receiving either semaglutide saline-placebo. PET/CT imaging done before after 16-weeks intervention. Three different radiotracers used:...
Polymeric micelles in nanomedicine are often cross‐linked to prevent disintegration vivo . This typically requires clinically problematic chemicals or laborious procedures. In addition, cross‐linking may interfere with advanced release strategies. Despite this, it is not investigated whether necessary for efficient drug delivery. We used positron emission tomography (PET) imaging 64 Cu demonstrate general methodology real‐time investigations of micelle stability. Triblock copolymers...
Abstract Atherosclerosis is a chronic inflammatory disease of the larger arteries that may lead to cardiovascular events. Identification patients at highest risk events challenging, but molecular imaging using positron emission tomography (PET) prove useful. The aim this study was evaluate and compare head-to-head three different PET tracers. Furthermore, tracer uptake compared gene expression alterations arterial vessel wall. Male New Zealand White rabbits (control group; n = 10,...
Abstract Background Translational molecular imaging using Positron Emission Tomography/Computed Tomography (PET/CT) and Transesophageal Echocardiography (TEE) are powerful non-invasive tools for investigation monitoring of cardiovascular functions. Following myocardial infarction (MI), formation new blood vessels (angiogenesis) is importance in the healing process can be assessed with PET tracer 68Ga-NODAGA-E[(cRGDyK)]2 (68Ga-RGD). Purpose The purpose study was to assess angiogenesis a...
Abstract Atherosclerosis is a chronic inflammatory disease of the larger arteries that may lead to cardiovascular events. Identification patients at highest risk events challenging, but molecular imaging using positron emission tomography (PET) prove useful. The aim this study was evaluate and compare head-to-head three different PET tracers. Furthermore, tracer uptake compared gene expression alterations arterial vessel wall. Methods Male New Zealand White rabbits (control group; n=10,...