Lazha Sharief

ORCID: 0000-0002-7469-2500
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About
Contact & Profiles
Research Areas
  • Ocular Diseases and Behçet’s Syndrome
  • Retinal and Optic Conditions
  • Retinal Diseases and Treatments
  • Systemic Lupus Erythematosus Research
  • Sarcoidosis and Beryllium Toxicity Research
  • Vasculitis and related conditions
  • Ocular Infections and Treatments
  • Mast cells and histamine
  • Autoimmune Bullous Skin Diseases
  • Retinal Imaging and Analysis
  • Autoimmune and Inflammatory Disorders
  • Otitis Media and Relapsing Polychondritis
  • Drug-Induced Ocular Toxicity
  • CNS Lymphoma Diagnosis and Treatment
  • Syphilis Diagnosis and Treatment
  • Intraocular Surgery and Lenses

University College London
2015-2023

Moorfields Eye Hospital
2015-2023

King's College Hospital NHS Foundation Trust
2023

Moorfields Eye Hospital NHS Foundation Trust
2019-2020

National Health Service
2020

King's College Hospital
2020

Hawler Medical University
2017-2018

Institute of Ophthalmology
2015-2018

Comparison of sarcoid uveitis with other non-infectious treatment and visual outcomes.Retrospective study 287 eyes 1517 (15,029 eye-years follow-up).Sarcoid patients presented at age 43.1 ± 0.8 years, 66.2% were female. Panuveitis was the most frequent presentation (48.3%), 90.1% bilateral. Moderate loss (≤20/50) developed in 19 (6.6%), severe (≤20/200) 13 (4.5%). Sarcoid had better outcomes than (10-year BCVA anterior 0.06 vs 0.24 p = .002; posterior disease 0.17 0.38 .001). Oral...

10.1080/09273948.2022.2032189 article EN Ocular Immunology and Inflammation 2022-02-24

Cataract is one of the most common complications associated with uveitis, and leading cause vision loss in these patients.The study aimed to evaluate effect phacoemulsification on long-term clinical outcome inflammation control uveitis patients.Longitudinal study.Of 1907 eyes 309 underwent were compared a group 300 phakic uveitis.The risk macular oedema pseudophakic group. The rates corticosteroids administration relapse also measured preoperative period.Change activity post by measuring...

10.1111/ceo.13369 article EN Clinical and Experimental Ophthalmology 2018-08-07

Background: Examining the effect of antibiotic resistance, use intravitreal antibiotics and systemic corticosteroids on visual outcome eyes with acute endophthalmitis. Methods: We included 226 endophthalmitis, treated using a standardized protocol. Visual up to 12 months was assessed related biopsy results, resistance treatment regimens. Results: Vitreous biopsies were more likely be culture-positive (41.1%) than anterior chamber (21.6%, p < 0.0001). Antibiotic for amikacin found in 19...

10.3390/antibiotics11070843 article EN cc-by Antibiotics 2022-06-23

Introduction: Inflammatory choroidal neovascularization (iCNV) is a significant complication of uveitis, leading to vision loss in many cases. Recent advances retinal imaging and the use anti-vascular endothelial growth factor (VEGF) agents, have led early diagnose treatment, preventing visual deterioration.Areas covered: This review discusses epidemiology, pathogenesis, conditions that are complicated by iCNV. We further describe diagnosis methods treatment approaches iCNV.Expert opinion:...

10.1080/17469899.2021.1842196 article EN Expert Review of Ophthalmology 2020-11-09

ObjectiveTo assess the efficacy of simvastatin 80mg/day versus placebo in patients with non-infectious non-anterior uveitis receiving prednisolone ≥10mg/day.DesignRandomized, double-masked, controlled trialSubjectsAdult on oral dose ≥10 mg/day.MethodsPatients were randomly assigned at a 1:1 ratio to receive either or placebo. 32 enrolled (16 each arm) all whom completed primary endpoint and 21 reached two-year visit (secondary end points).Main outcome measuresThe was mean reduction daily 12...

10.1016/j.xops.2023.100333 article EN cc-by-nc-nd Ophthalmology Science 2023-05-19
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