Abhimanyu Sharma

ORCID: 0000-0002-7469-9120
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About
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Research Areas
  • Drug Solubulity and Delivery Systems
  • Analytical Methods in Pharmaceuticals
  • Microtubule and mitosis dynamics
  • Cellular transport and secretion
  • Advanced Drug Delivery Systems
  • Bacteriophages and microbial interactions
  • SARS-CoV-2 and COVID-19 Research
  • Lipid Membrane Structure and Behavior
  • Dental Research and COVID-19
  • Computational Drug Discovery Methods
  • SARS-CoV-2 detection and testing
  • Cellular Mechanics and Interactions
  • Infection Control and Ventilation
  • Scientific and Engineering Research Topics
  • Drug-Induced Hepatotoxicity and Protection
  • Healthcare and Environmental Waste Management
  • Complement system in diseases
  • Evolutionary Psychology and Human Behavior
  • Micro and Nano Robotics
  • Photosynthetic Processes and Mechanisms
  • Advancements in Transdermal Drug Delivery
  • Biomedical Research and Pathophysiology
  • Electrospun Nanofibers in Biomedical Applications
  • Pharmacological Effects of Natural Compounds
  • Blood donation and transfusion practices

Chaudhary Devi Lal University
2017-2025

North Carolina State University
2022

University of Utah
2018-2021

ESIC Hospital
2020

Greater reproductive variance among males than females is presented as a component of natural selection's influence in determining preferential treatment the inheritance wealth. In conjunction, transmission sex chromosomes and their attendant probabilities carrying genes identical by descent are traced for several generations order to illustrate male bias species whose heterogametic (XY) while female homogametic (XX). The effect this on coefficients relationship (direct additive) leads...

10.1086/201799 article EN Current Anthropology 1976-12-01

SARS-CoV-2 virus is the causative agent of COVID-19. Here we demonstrate that non-infectious like particles (VLPs) can be assembled by co-expressing viral proteins S, M and E in mammalian cells. The VLPs possess S protein spikes on particle exterior, making them ideal for vaccine development. range shape from spherical to elongated with a characteristic size 129 ± 32 nm. We further show dried ambient conditions retain their structural integrity upon repeated scans Atomic Force Microscopy up...

10.1038/s41598-020-78656-w article EN cc-by Scientific Reports 2020-12-14

The eukaryotic cell's microtubule cytoskeleton is a complex 3D filament network. Microtubules cross at wide variety of separation distances and angles. Prior studies in vivo vitro suggest that cargo transport affected by intersection geometry. However, geometric complexity not yet widely appreciated as regulatory factor its own right, mechanisms underlie this mode regulation are well understood. We have used our recently reported manipulation system to build crossings de novo purified...

10.1073/pnas.1707936115 article EN Proceedings of the National Academy of Sciences 2018-01-02

Pulsatile drug delivery systems have been a major field of research recently.It is the most interesting time-specific and site-specific system.This system designed for chronopharmacotherapy which based on circadian rhythm.This means these will deliver at time when disease displays it's morbid mortal state within cycle.The use has investigated diseases like asthma, arthritis, ulcers, cardiovascular diseases, hypercholesterolemia, cancer etc. Various capsular, osmotic, single multiple unit...

10.21276/apjhs.2018.5.3.38 article EN Asian Pacific Journal of Health Sciences 2018-07-01

Changing paradigm in prosthodontics practice post COVID-19 outbreak - APRD- Print ISSN No: 2581-4796 Online No:- 2581-480X Article DOI 10.18231/j.aprd.2020.017, IP Annals of Prosthodontics and Restorative Dentistry-IP Ann Prosthodont Restor Dent

10.18231/j.aprd.2020.017 article EN IP Annals of Prosthodontics and Restorative Dentistry 2020-06-11

Recent pandemic virus SARS-CoV-2 is a global warning for the healthcare system. The spike protein of significant because two reasons. Firstly, this binds with human ACE2 (hACE2) receptor. Secondly, it has several antigenic regions that might be targeted vaccine development. However, structural analytical data not available.Here, we performed an analysis to understand subunits S glycoprotein (S gp) SARS-CoV-2. Further, secondary structure components and tertiary RBD was carried out. We also...

10.26355/eurrev_202102_24881 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2021-02-01

Abstract SARS-CoV-2 virus is the causative agent of COVID-19. Here we demonstrate that non-infectious like particles (VLPs) can be assembled by co-expressing viral proteins S, M and E in mammalian cells. The VLPs possess S protein spikes on particle exterior, making them ideal for vaccine development. range shape from spherical to elongated with a characteristic size 129 ± 32 nm. We further show dried ambient conditions retain their structural integrity upon repeated scans Atomic Force...

10.1101/2020.06.01.128058 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2020-06-01

Abstract The Endosomal Sorting Complexes Required for Transport (ESCRTs) mediate diverse membrane remodeling events. These activities typically require ESCRT-III proteins to stabilize negatively-curved membranes, although recent work has indicated that certain ESCRT-IIIs also participate in positive-curvature shaping reactions. polymerize into membrane-binding filaments, but the structural basis negative versus positive curvature by these remains poorly understood. To learn how shape we...

10.1101/798181 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-10-11

The objective of the present study was to prepare immediate release tablets (IRTs) deflazacort by direct compression method. Two types superdisintegrants i.e. sodium starch glycolate (SSG) and Ac-Di-sol were used in formulation tablets. Twelve preliminary batches prepared varying concentration superdisintegrants. It found that containing Ac-Di-Sol disintegrated less time as compared glycolate. Values friability be more case Ac-Di-Sol. Attempts also made combination these resulted with...

10.22270/jddt.v9i2.2411 article EN Journal of Drug Delivery and Therapeutics 2019-03-15

10.1016/j.bbrc.2020.06.030 article EN publisher-specific-oa Biochemical and Biophysical Research Communications 2020-06-30

Biomedical waste management is one of the emerging causes for Hospital Acquired Infection, which very important to deal with due its significant impact on health and environment. generated in dental clinics hospitals if not managed properly, can create various hazards professionals, auxiliaries, patients other care service providers who work office. Each provider should have knowledge about handling disposal biomedical waste. In this article different methods during unprecedented times...

10.26480/jhcdc.03.2021.50.53 article EN Journal Of Healthcare In Developing Countries 2020-04-21

The objective of the present study was to prepare immediate release tablets (IRTs) valsartan by direct compression method. Two types superdisintegrants i.e. sodium starch glycolate (SSG) and Ac-Di-sol were used in formulation tablets. Twelve preliminary trial batches prepared varying concentration superdisintegrants. It found that containing Ac-Di-Sol disintegrated less time as compared glycolate. Values friability be more case Ac-Di-Sol. Attempts also made combination these resulted with...

10.22270/jddt.v9i2-s.2444 article EN Journal of Drug Delivery and Therapeutics 2019-04-15

An amendment to this paper has been published and can be accessed via a link at the top of paper.

10.1038/s41598-021-88846-9 article EN cc-by Scientific Reports 2021-04-26
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