Gabriela Silva

ORCID: 0000-0002-7479-8540
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Antibiotic Resistance in Bacteria
  • Vibrio bacteria research studies
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Escherichia coli research studies
  • Salmonella and Campylobacter epidemiology
  • Bacterial biofilms and quorum sensing
  • Enterobacteriaceae and Cronobacter Research
  • Education Pedagogy and Practices
  • Infections and bacterial resistance
  • Bacteriophages and microbial interactions
  • Photodynamic Therapy Research Studies
  • Gender, Sexuality, and Education
  • Nanoplatforms for cancer theranostics
  • Vector-borne infectious diseases
  • Noise Effects and Management
  • Bacterial Genetics and Biotechnology
  • Antibiotics Pharmacokinetics and Efficacy
  • Viral Infections and Vectors
  • Science and Education Research
  • Exercise and Physiological Responses
  • Laser Applications in Dentistry and Medicine
  • Gut microbiota and health
  • Porphyrin and Phthalocyanine Chemistry
  • Bee Products Chemical Analysis
  • Vector-Borne Animal Diseases

Universidade Federal dos Vales do Jequitinhonha e Mucuri
2015-2025

Universidade do Oeste Paulista
2025

University of Coimbra
2015-2024

Universidade Federal do Rio de Janeiro
2006-2024

Centro de Neurociências e Biologia Celular
2014-2024

North Carolina State University
2024

Altera (United States)
2024

Google (United States)
2024

Universidad Columbia del Paraguay
2024

Universidade Estadual de Campinas (UNICAMP)
2024

We have investigated to what extent natural transformation acting on free DNA substrates can facilitate transfer of mobile elements including transposons, integrons and/or gene cassettes between bacterial species. Naturally transformable cells Acinetobacter baylyi were exposed from integron-carrying strains the genera Acinetobacter, Citrobacter, Enterobacter, Escherichia, Pseudomonas, and Salmonella determine nature frequency transfer. Exposure various sources resulted in acquisition...

10.1371/journal.ppat.1002837 article EN cc-by PLoS Pathogens 2012-08-02

Microbiota dysbiosis and impaired barrier function are among the most prominent features of inflammatory bowel disease. In gastrointestinal tract, hydrogen sulfide (H(2)S) is an important regulator mucosal homeostasis. We hypothesized that H(2)S promotes resolution colonic inflammation through actions on microbiota biofilm mucus barrier.We used mice genetically deficient for a key enzyme production (cystathionine γ-lyase) pharmacologically inhibited during colitis in wild-type mice. tested...

10.1097/mib.0000000000000345 article EN Inflammatory Bowel Diseases 2015-03-04

Integrons are genetic elements first described at the end of 1980s. Although most integrons were initially in human clinical isolates, they have now been identified many non-clinical environments, such as water and soil. present ≈10% sequenced bacterial genomes frequently linked to mobile (MGEs); particularly class 1 integrons. Genetic linkage a diverse set MGEs facilitates horizontal transfer within between populations species. The mechanistic aspects limiting will therefore limit However,...

10.4161/mge.22967 article EN Mobile Genetic Elements 2012-09-01

Food contamination due to the presence of microorganisms is a serious problem. New food preservation systems are being studied kill or inhibit spoilage and pathogenic that contaminate reduce shelf life products. Chitosan films with potential application have witnessed great developments during last years. cationic polysaccharide ability form possess antimicrobial properties. It water-insoluble but can be dissolved in acidic solutions. In present work, three different acids (acetic, lactic...

10.3390/polym13010001 article EN Polymers 2020-12-22

Gram-negative bacteria and in biofilms are very difficult to eradicate the most antibiotic-resistant bacteria. Therapeutic alternatives less susceptible mechanisms of resistance urgently needed respond an alarming increase resistant nosocomial infections. Antibacterial photodynamic inactivation (PDI) generates oxidative stress that triggers multiple cell death more counteract by We explore PDI multidrug-resistant bacterial strains collected from patients show how positive charge distribution...

10.1021/acsinfecdis.9b00379 article EN ACS Infectious Diseases 2020-01-08

Abstract Bacterial infections are a global health concern, particularly due to the increasing resistance of bacteria antibiotics. Multi-drug (MDR) is considerable challenge, and novel approaches needed treat bacterial infections. Photodynamic inactivation (PDI) microorganisms increasingly recognized as an effective method inactivate broad spectrum overcome mechanisms. This study presents synthesis new cationic 5,15-di-imidazolyl porphyrin derivative impact n-octanol/water partition...

10.1007/s43630-024-00581-y article EN cc-by Photochemical & Photobiological Sciences 2024-05-12

The small intestine is a significant site of ulceration and bleeding induced by nonsteroidal anti-inflammatory drugs (NSAIDs). pathogenesis poorly understood. present study explored the roles bile, bacteria, enterohepatic circulation to NSAID enteropathy, using both conventional (naproxen) gastrointestinal-safe naproxen derivative (ATB-346), as well proton pump inhibitors (PPIs). Rats were treated orally with or equimolar doses ATB-346 over 5-day period, without PPI administration,...

10.1152/ajpgi.00066.2015 article EN AJP Gastrointestinal and Liver Physiology 2015-04-17

Horizontal gene transfer events provide the basis for extensive dissemination of antimicrobial resistance traits between bacterial populations. Conjugation is considered to be most frequent mechanism behind new acquisitions in clinical pathogens but does not fully explain patterns seen some genera. Gene by natural transformation has been described numerous isolates, including Acinetobacter species. The main aim this study was determine what extent clinical, resistant spp. express competence...

10.3390/microorganisms7020030 article EN cc-by Microorganisms 2019-01-24

Carbapenemases, a class of enzymes specialized in the hydrolysis carbapenems, represent significant threat to global public health. These are classified into different Ambler’s classes based on their active sites, categorized A, D, and B. Among most prevalent types IMI/NMC-A, KPC, VIM, IMP, OXA-48, commonly associated with pathogenic species such as Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa. The emergence dissemination carbapenemase-producing bacteria have raised...

10.3390/antibiotics13060557 article EN cc-by Antibiotics 2024-06-14

Background: Humic acid (HA) is a bioproduct that can be extracted from different sources and has anti-inflammatory properties have been little explored in the treatment prevention of Periodontal Disease (PD). Thus, we aimed to investigate effects oral administration HA on progression PD rats. Methods: Twenty-four male Wistar rats were distributed into three experimental groups (Control/ Sham, PD, + HA). was administered by gavage (80 mg/kg/day) for 28 days, induced 14 days after beginning...

10.2174/0115680266302476240510115556 article EN Current Topics in Medicinal Chemistry 2024-05-20
Coming Soon ...