A5053203090- Reproductive Biology and Fertility
- Sperm and Testicular Function
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Ovarian function and disorders
- Reproductive Health and Technologies
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Biosensors and Analytical Detection
- Renal and related cancers
- Advanced biosensing and bioanalysis techniques
- Vaccine Coverage and Hesitancy
- Cancer Risks and Factors
- Ectopic Pregnancy Diagnosis and Management
- Birth, Development, and Health
- Pluripotent Stem Cells Research
- Genetic Syndromes and Imprinting
- Diabetes Management and Research
- COVID-19 Clinical Research Studies
- Diabetes Management and Education
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- COVID-19 epidemiological studies
- Oil, Gas, and Environmental Issues
- Migration, Health and Trauma
- Influenza Virus Research Studies
University of California, San Francisco
2017-2022
United in Health
2022
Bay Area Hospital
2021-2022
Institute for Reproductive Health
2022
University of Lisbon
2019
Reproductive Science Center
2015
University of California, Davis
2012
Does microfluidic sorting improve the selection of sperm with lower DNA fragmentation over standard density-gradient centrifugation? Microfluidic unprocessed semen allows for clinically usable, highly motile nearly undetectable levels fragmentation. devices have been explored to sort and morphologically normal from a raw sample without centrifugation; however, it is uncertain whether damage reduced in this process. This blinded, controlled laboratory study differences analysis parameters...
COVID-19 vaccine coverage in the Latinx community depends on delivery systems that overcome barriers such as institutional distrust, misinformation, and access to care. We hypothesized a community-centered vaccination strategy included mobilization, vaccination, "activation" components could successfully reach an underserved population, utilizing its social networks boost coverage.
SARS-CoV-2 rapid antigen tests are an important public health tool.
Characterizing the clinical symptoms and evolution of community-based SARS-CoV-2 infections may inform health practitioners public officials in a rapidly changing landscape population immunity viral variants.To compare COVID-19 among people testing positive with rapid antigen test (RAT) during Omicron BA.1 variant period (December 1, 2021, to January 30, 2022) pre-Delta (January 10 May 31, 2021) Delta (June 1 November periods assess duration RAT positivity surge.This cross-sectional study...
Abstract In 731 persons seeking COVID-19 testing at a walk-up San Francisco community site in January 2022, simultaneous nasal rapid antigen (BinaxNOW™) and RT-PCR was performed. There were 296 (40.5%) positive tests by RT-PCR; 98.5% of random sample (N=67) the omicron variant. Sensitivity single test 95.2% (95% CI 92-98%); 82.1% 77-87%) 65.2% 60-71%) for Ct threshold < 30, 35 no threshold, respectively. We also compared BinaxNOW™ to from oral cheek swabs (N=75); specimen significantly...
Abstract STUDY QUESTION Does processing of spermatozoa for IVF with ICSI by a microfluidic sperm separation device improve embryo quality compared density-gradient centrifugation? SUMMARY ANSWER Patients randomized to preparation had similar cleavage- and blastocyst-stage clinical ongoing pregnancy rates those who underwent standard ICSI. WHAT IS KNOWN ALREADY Microfluidic can isolate use minimal DNA fragmentation but unclear impact on outcomes. DESIGN, SIZE, DURATION A prospective...
Abstract Background COVID-19 vaccine coverage in the Latinx community depends on delivery systems that overcome barriers such as institutional distrust, misinformation, and access to care. We hypothesized a community-centered vaccination strategy included mobilization, vaccination, “activation” components could successfully reach an underserved population, utilizing its social networks boost coverage. Methods Findings Our community-academic-public health partnership, “Unidos en Salud,”...
<h3>Importance</h3> Community-based COVID-19 testing and vaccination programs play a crucial role in mitigating racial ethnic disparities service delivery. They also represent platform that can be leveraged to expand access for chronic diseases, including diabetes, disproportionately affect the Latinx community other marginalized communities. <h3>Objective</h3> To evaluate outcomes associated with diabetes strategy designed reach low-income persons by leveraging infrastructure trust...
The ability to understand whether embryos survive the thaw process is crucial transferring competent that can lead pregnancy. objective of this study was develop a proof concept deep learning model capable assisting embryologist assessment survival thawed blastocysts prior embryo transfer. A developed using 652 labeled time-lapse videos freeze-thaw blastocysts. evaluated against and along embryologists on test set 99 blastocysts, images obtained at 0.5 h increments from 0 3 post-thaw....
Abstract Importance Characterizing clinical symptoms and evolution of community-based SARS Co-V-2 infections can inform health practitioners public officials in a rapidly changing landscape population immunity viral variants. Objective To characterize COVID-19 during the Omicron period compared to pre-Delta Delta variant periods assess duration BinaxNOW rapid antigen test positivity surge. Design, Setting, Participants This surveillance study was undertaken between January 2021-January 2022,...
Do embryos from sibling oocytes assigned to distinct single-step media culture systems demonstrate differences in early embryo development, morphokinectics or aneuploidy rates?Embryo quality, morphokinetic parameters and rates trophectoderm biopsy were similar between cultured the time of gamete isolation.Studies on effect commercially available have demonstrated inconsistent impact human embryonic morphokinetics, clinical outcomes. In addition, these studies been primarily randomized at...
To describe morphokinetic parameters and ploidy among low-quality blastocysts not meeting the criteria for clinical use.Prospective cohort study.Academic medical center.Two hundred patients undergoing in vitro fertilization between February 2018 November 2019.All embryos were cultured a time-lapse incubator. All expanded underwent preimplantation genetic testing aneuploidy using next-generation sequencing.Static blastocyst morphology grading; parameters, including time to each cell division...
ABSTRACT Background COVID-19 oral treatments require initiation within 5 days of symptom onset. Although antigen tests are less sensitive than RT-PCR, rapid results could facilitate entry to treatment. As SARS-CoV-2 variants and host immunity evolve, it is important characterize the use case for treatment entry. Methods We collected anterior nasal swabs BinaxNOW RT-PCR testing clinical data at a walk-up, community site in San Francisco, California between January June 2022. genomic sequences...