A5020582140- Cancer, Hypoxia, and Metabolism
- Phytochemistry and Bioactive Compounds
- Cancer, Lipids, and Metabolism
- Helicobacter pylori-related gastroenterology studies
- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Cancer Treatment and Pharmacology
- Berberine and alkaloids research
Tianjin Medical University General Hospital
2024
Guangxi Medical University
2022-2023
Gastric cancer (GC) is marked by high incidence, malignancy, and poor prognosis. Understanding its development mechanisms discovering effective drugs are urgent needs. Elevated oxidative stress levels in GC patients have been linked to disease progression. Berberine, an isoquinoline alkaloid from Coptis chinensis, exhibits strong anti-GC properties without notable side effects. However, impact regarding remain unclear. This study aims explore berberine's through network pharmacology validate...
To explore the underlying mechanism of total flavonoids Litchi seed (TFLS) in treating prostate cancer (PCa).Cell Counting Kit-8 (CCK-8), EdU incorporation assay, trypan blue dye assay and colony formation were employed to evaluate effect TFLS on PCa vitro. The xenograft mouse model was established anti-tumour vivo. Alterations metabolic profiles PC3 cells serum obtained by untargeted metabolomics. Combination with metabolomics analysis network pharmacology strategies, potential targets...