A5087416765- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Cancer, Stress, Anesthesia, and Immune Response
- Monoclonal and Polyclonal Antibodies Research
- Cancer Immunotherapy and Biomarkers
- Stress Responses and Cortisol
- Per- and polyfluoroalkyl substances research
- Effects and risks of endocrine disrupting chemicals
- Adipokines, Inflammation, and Metabolic Diseases
- Toxic Organic Pollutants Impact
- Neurogenesis and neuroplasticity mechanisms
Istituto Superiore di Sanità
2010-2021
Social isolation is a powerful stressor capable of affecting brain plasticity and function. In the case breast cancer, previous data indicate that stressful experiences may contribute to worse prognosis, activating neuroendocrine metabolism pathways, although mechanisms underlying these effects are still poorly understood. this study, we tested hypothesis chronic stress (IS) boost hypothalamic–pituitary–adrenal (HPA) axis activity, leading changes in hypothalamic expression genes modulating...
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Purpose: This study was aimed at evaluating the feasibility, safety, immunological and clinical responses in patients with Follicular lymphoma (FL) treated monocyte-derived dendritic cells generated presence of interferon-alpha GM-CSF (IFN-DC) combination low doses Rituximab (R). Experimental design: Firstly, we analyzed vitro vivo properties IFN-DC against FL. Thus, performed a phase I trial 8 refractory relapsed FL based on sequential intranodal injections low-dose R unloaded report...