A5019703763- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Adolescent Sexual and Reproductive Health
- COVID-19 epidemiological studies
- Opioid Use Disorder Treatment
- HIV Research and Treatment
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Syphilis Diagnosis and Treatment
- Alzheimer's disease research and treatments
- SARS-CoV-2 detection and testing
- Hepatitis C virus research
- Reproductive tract infections research
- Sex work and related issues
- Data-Driven Disease Surveillance
- COVID-19 and Mental Health
- Hepatitis B Virus Studies
- Genetics and Neurodevelopmental Disorders
- Global Maternal and Child Health
- HIV-related health complications and treatments
- Statistical Methods in Clinical Trials
- Liver Disease Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Primary Care and Health Outcomes
- Autism Spectrum Disorder Research
Emory University
2020-2025
Acadia Pharmaceuticals (United States)
2024
Emory and Henry College
2024
Cooper Green Mercy Hospital
2024
Mercy Health
2024
Georgia State University
2019-2023
University of Alabama at Birmingham
2023
UAB Medicine
2023
Eisai (United States)
2019-2022
University of Michigan
2022
Lecanemab (BAN2401), an IgG1 monoclonal antibody, preferentially targets soluble aggregated amyloid beta (Aβ), with activity across oligomers, protofibrils, and insoluble fibrils. BAN2401-G000-201, a randomized double-blind clinical trial, utilized Bayesian design response-adaptive randomization to assess 3 doses 2 regimens of lecanemab versus placebo in early Alzheimer's disease, mild cognitive impairment due disease (AD) AD dementia.
Background. Herpes simplex virus types 1 and 2 (HSV-1 HSV-2) are common infections with serious sequelae. HSV-1 is an increasingly important cause of genital herpes in industrialized countries. Methods. Using nationally representative data from the National Health Nutrition Examination Survey (NHANES), we examined HSV-2 seroprevalence among 14- to 49-year-olds United States. We estimated 1999–2004 2005–2010, stratified by sociodemographic characteristics sexual behaviors. also reviewed...
Abstract Background Public health data signal increases in the number of people who inject drugs (PWID) United States during past decade. An updated PWID population size estimate is critical for informing interventions and policies aiming to reduce injection-associated infections overdose, as well provide a baseline assessments pandemic-related changes injection drug use. Methods We used modified multiplier approach adults injected 2018. deduced estimated nonfatal overdose events among from...
Free radical activity has been implicated in the development of diabetic vascular complications Type 1 diabetes. The aim present study was to investigate levels free scavengers, particularly erythrocyte superoxide dismutase, plasma and lysate thiol, caeruloplasmin 22 2 patients clinically complications, 15 comparable non‐diabetic control subjects. concentration (median (range)) both dismutase (23 (10–39) vs 45 (25–75) μmol I −1 ; p < 0.001) thiol (374 (172–523) 460 (386–595) 0.01) were...
Background AIDSVu is a public resource for visualizing HIV surveillance data and other population-based information relevant to prevention, care, policy, impact assessment. Objective The site, AIDSVu.org, aims make about the US epidemic widely available, easily accessible, locally inform health decision making. Methods develops visualizations, maps, downloadable datasets using results from systems, sources of (eg, Census national probability surveys), developed specifically display...
To examine racial/ethnic and gender disparities in antiretroviral (ART) use viral suppression among HIV-infected persons care identify factors that might account for observed disparities. The Medical Monitoring Project (MMP) is a complex sample survey of adults receiving medical the United States. We used weighted interview record data collected 06/2009 to 05/2012 estimate prevalence ART gender-stratified groups. χ2 tests significant differences outcomes between white men versus other...
Evaluation of sexual behaviors is essential to better understand the epidemiology sexually transmitted infections and their sequelae.The National Health Nutrition Examination Surveys (NHANES) an ongoing probability sample survey US population. Using NHANES behavior data from 1999 2012, we performed following: (1) trend analyses among adults aged 25 59 years by 10-year birth cohorts (2) descriptive participants 14 24 years. Sex was defined as vaginal, anal, or oral sex.Among years, median age...
Existing health disparities based on race and ethnicity in the United States are contributing to morbidity mortality during coronavirus disease (COVID-19) pandemic. We conducted an online survey of American adults assess similarities differences by with respect COVID-19 symptoms, estimates extent pandemic, knowledge control measures, stigma.
Peter G. Szilagyi, MD, MPH; Kyla Thomas, PhD; Megha D. Shah, MPH, MS; Nathalie Vizueta, Yan Cui, Sitaram Vangala, Arie Kapteyn, PhD
Hepatitis C virus (HCV) infection is a leading cause of liver‐related morbidity and mortality, more than 2 million adults in the United States are estimated to be currently infected. Reducing HCV burden will require an understanding demographic disparities targeted efforts reduce prevalence populations with disproportionate disease rates. We modeled state‐level estimates hepatitis among U.S. by sex, birth cohort, race during 2013‐2016. National Health Nutrition Examination Survey data were...
The National Health and Nutrition Examination Survey (NHANES) underestimates the true prevalence of HCV infection. By accounting for populations inadequately represented in NHANES, we created 2 models to estimate national hepatitis C among US adults during 2017-2020.
Background. The Ryan White HIV/AIDS Program (RWHAP) provides persons infected with human immunodeficiency virus (HIV) services not covered by other healthcare payer types. Limited data exist to inform policy decisions about the most appropriate role for RWHAP under Patient Protection and Affordable Care Act (ACA). Methods. We assessed associations between assistance antiretroviral therapy (ART) prescription viral suppression. used from Medical Monitoring Project, a surveillance system...
To examine trends in racial/ethnic disparities antiretroviral therapy (ART) prescription and viral suppression among HIV-infected persons care, overall men who have sex with (MSM), from 2009 to 2013.The Medical Monitoring Project (MMP) is a complex sample survey of adults receiving medical care the United States.We used weighted interview record data collected June 2009-May 2014 estimate prevalence ART groups MSM.We found significant increases all 2013, both MSM. By MSM, Hispanic-white...
Abstract Background SARS-CoV-2 virus testing for persons with COVID-19 symptoms, and contact tracing those positive, will be critical to successful epidemic control. Willingness of experiencing symptoms seek may determine the success this strategy. Methods A cross-sectional online survey in United States measured willingness if feeling ill under different specimen collection scenarios: home-based saliva, swab, drive-through facility clinic-based swab. Instructions clarified that...
Abstract Background Although reported condom use between female sex workers and their clients is high in Ethiopia, with regular, non-paying partners remains low, posing a substantial risk of HIV infection to workers, the general population. Previous studies have identified synergistic effects substance abuse, violence risk, but few examined these inter-relationships among partners. This study explored associations work-related violence, alcohol abuse inconsistent establishment-based Adama...