A5024434281- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Malaria Research and Control
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- Herpesvirus Infections and Treatments
- Homelessness and Social Issues
- Insect symbiosis and bacterial influences
- Vaccine Coverage and Hesitancy
- LGBTQ Health, Identity, and Policy
- Data-Driven Disease Surveillance
- Genital Health and Disease
- HIV/AIDS drug development and treatment
- Respiratory viral infections research
- Zoonotic diseases and public health
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
Centers for Disease Control and Prevention
2016-2025
Puerto Rico Department of Health
2018-2025
National Center for Emerging and Zoonotic Infectious Diseases
2017-2024
Centers for Disease Control and Prevention
2018-2024
Vector & Vector-Borne Diseases Research Institute
2024
AID Atlanta
2024
Government of the United States of America
2022-2023
Ponce Health Sciences University
2022-2023
United States Virgin Islands Department of Health
2021-2023
Micronesia Conservation Trust
2023
Vectorborne diseases are major causes of death and illness worldwide. In the United States, most common vectorborne pathogens transmitted by ticks or mosquitoes, including those causing Lyme disease; Rocky Mountain spotted fever; West Nile, dengue, Zika virus diseases. This report examines trends in occurrence nationally reportable during 2004-2016.Data reported to National Notifiable Diseases Surveillance System for 16 notifiable 2004-2016 were analyzed; findings tabulated disease, vector...
Human immunodeficiency virus (HIV) transmission risk is primarily dependent on behavior (sexual and injection drug use) HIV viral load. National goals emphasize maximizing coverage along the care continuum, but effect prevention unknown.To estimate rate number of transmissions attributable to persons at each following 5 continuum steps: infected undiagnosed, diagnosed not retained in medical care, prescribed antiretroviral therapy, therapy virally suppressed, suppressed.A multistep, static,...
To estimate the frequency and duration of detectable Zika virus (ZIKV) RNA in human body fluids, we prospectively assessed a cohort newly infected participants Puerto Rico.We evaluated samples obtained from 150 (including 55 men) whom ZIKV was detected on reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay urine or blood an enhanced arboviral clinical surveillance site. We collected serum, urine, saliva, semen, vaginal secretions weekly for first month then at 2, 4, 6 months. All...
Background. Pre-exposure prophylaxis (PrEP) is an effective prevention tool for people at substantial risk of acquiring human immunodeficiency virus (HIV). To monitor the current state PrEP use among men who have sex with (MSM), we report on willingness to and utilization. assess whether MSM subpopulations highest infection indications according 2014 clinical guidelines, estimated by demographics. Methods. We analyzed data from cycle National HIV Behavioral Surveillance (NHBS) system tested...
In the United States, 9% of human immunodeficiency virus (HIV) infections diagnosed in 2015 were attributed to injection drug use (1). 2015, 79% diagnoses HIV infection among persons who inject drugs occurred urban areas (2). To monitor prevalence and associated behaviors drugs, CDC's National Behavioral Surveillance (NHBS) conducts interviews testing selected metropolitan statistical (MSAs) (3). The 20 MSAs was 7%. a behavioral analysis HIV-negative an estimated 27% receptively shared...
Abstract Dengue is the most prevalent mosquito-borne viral disease in humans, and cases are continuing to rise globally. In particular, islands Caribbean have experienced more frequent outbreaks, all four dengue virus (DENV) serotypes been reported region, leading hyperendemicity increased rates of severe disease. However, there significant variability regarding surveillance reporting between islands, making it difficult obtain an accurate understanding epidemiological patterns Caribbean. To...
Dengue and Zika viruses are closely related mosquitoborne flaviviruses with similar transmission cycles, distribution throughout the tropics subtropics, disease manifestations including fever, rash, myalgia, arthralgia. For patients suspected dengue or virus disease, nucleic acid amplification tests (NAATs) preferred method of diagnosis. Immunoglobulin M (IgM) antibody testing can identify additional infections remains an important tool for diagnosis these diseases, but interpreting results...
Evaluate changes in condomless anal sex at last among men who have with (MSM) and assess if these are associated the adoption of serosorting biomedical prevention.The National HIV Behavioral Surveillance is a crosssectional survey done up to 21 cities 2005, 2008, 2011 2014.MSM were recruited through venue-based sampling. Among reporting least one male partner, we evaluated partner (1) HIV-concordant (proxy for serosorting) or (2) HIV-discordant (discordant/unknown) status. We hypothesized...
Objective: To estimate HIV prevalence, annual incidence density, and factors associated with infection among young MSM in the United States. Design: The 2008 National Behavioral Surveillance System (NHBS), a cross-sectional survey conducted 21 US cities. Methods: NHBS respondents included analysis were aged 18–24 valid test who reported at least one male sex partner past year. We calculated prevalence estimated density (number of infections/total number person-years risk). Generalized...
Risk for severe coronavirus disease 2019 (COVID-19)-associated illness (illness requiring hospitalization, intensive care unit [ICU] admission, mechanical ventilation, or resulting in death) increases with increasing age as well presence of underlying medical conditions that have shown strong and consistent evidence, including chronic obstructive pulmonary disease, cardiovascular diabetes, kidney obesity (1-4).Identifying describing the prevalence these at local level can help guide...
Dengue is a vectorborne infectious disease caused by dengue viruses (DENVs), which are predominantly transmitted Aedes aegypti and albopictus mosquitos. four closely related (DENV-1-4), person can be infected with each serotype for total of infections during their lifetime. Areas where endemic in the United States its territories freely associated states include Puerto Rico, American Samoa, U.S. Virgin Islands, Federated Micronesia, Republic Marshall Palau. This report summarizes...
Dengue is one of the most common vectorborne flaviviral infections globally, with frequent outbreaks in tropical regions. In 2019 and 2020, Pan American Health Organization reported approximately 5.5 million dengue cases from Americas, highest number on record. United States, local virus (DENV) transmission has been all U.S. territories, which are characterized by climates that highly suitable for Aedes species mosquitoes, vector transmits dengue. endemic territories Samoa, Puerto Rico,...
Abstract During May 2022–April 2023, dengue virus serogroup 3 was identified among 601 travel-associated and 61 locally acquired cases in Florida, USA. All 203 sequenced genomes belonged to the same genotype III lineage revealed potential transmission chains which most occurred shortly after introduction, with little sustained transmission.
Distinguishing between non-severe and severe dengue is crucial for timely intervention reducing morbidity mortality. World Health Organization (WHO)-recommended warning signs offer a practical approach clinicians but have limited sensitivity specificity. This study aims to evaluate machine learning (ML) model performance compared WHO-recommended in predicting among laboratory-confirmed cases Puerto Rico. We analyzed data from Rico's Sentinel Enhanced Dengue Surveillance System (May...
Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission facilitated by the large number undiagnosed cases, frequency atypical occurrence asymptomatic shedding. The lack easy, affordable diagnostic methods specific antiviral treatment in countries with low middle income great concern, given ability GUD to enhance HIV acquisition. With rising prevalence contributing increase...