A5076485059- Mosquito-borne diseases and control
- Viral Infections and Vectors
- COVID-19 epidemiological studies
- Photonic and Optical Devices
- Malaria Research and Control
- Optical Network Technologies
- Semiconductor Lasers and Optical Devices
- Viral Infections and Outbreaks Research
- SARS-CoV-2 and COVID-19 Research
- Influenza Virus Research Studies
- Advanced Fiber Laser Technologies
- Zoonotic diseases and public health
- Data-Driven Disease Surveillance
- Virology and Viral Diseases
- Obesity, Physical Activity, Diet
- Advanced Photonic Communication Systems
- Respiratory viral infections research
- Insect symbiosis and bacterial influences
- Vaccine Coverage and Hesitancy
- Artificial Intelligence in Healthcare and Education
- COVID-19 and Mental Health
- Disaster Response and Management
- Food Security and Health in Diverse Populations
- SARS-CoV-2 detection and testing
- Dengue and Mosquito Control Research
Puerto Rico Department of Health
2017-2025
Centers for Disease Control and Prevention
2016-2025
AID Atlanta
2024
National Center for Emerging and Zoonotic Infectious Diseases
2013-2024
Vanderbilt University Medical Center
2020-2024
Centers for Disease Control and Prevention
2017-2024
Vector & Vector-Borne Diseases Research Institute
2024
Government of the United States of America
2023
Swedish Veterinary Agency
2023
University of Puerto Rico System
2023
To estimate the frequency and duration of detectable Zika virus (ZIKV) RNA in human body fluids, we prospectively assessed a cohort newly infected participants Puerto Rico.We evaluated samples obtained from 150 (including 55 men) whom ZIKV was detected on reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay urine or blood an enhanced arboviral clinical surveillance site. We collected serum, urine, saliva, semen, vaginal secretions weekly for first month then at 2, 4, 6 months. All...
https://www.cdc.gov/coronavirus/2019-ncov/cases-in-us.html.† Hotspot counties are defined as those meeting all of the following baseline criteria: 1) >100 new COVID-19 cases in most recent 7 days, 2) an increase 7-day incidence over preceding incidence, 3) a decrease <60% or 3-day and 4) ratio to 30-day exceeds 0.31.In addition, hotspots must have met at least one >60% change incidence.Abbreviations: AI/AN = American Indian/Alaska Native; coronavirus disease 2019; NHPI Native Hawaiian/other...
Pregnant women living in or traveling to areas with local mosquito-borne Zika virus transmission are at risk for infection, which can lead severe fetal and infant brain abnormalities microcephaly (1). In February 2016, CDC recommended 1) routine testing infection of asymptomatic pregnant ongoing the first prenatal care visit, 2) retesting during second trimester who initially test negative, 3) signs symptoms consistent disease (e.g., fever, rash, arthralgia, conjunctivitis) any time...
Approximately 60 million persons in the United States live rural counties, representing almost one fifth (19.3%) of population.* In September 2020, COVID-19 incidence (cases per 100,000 population) counties surpassed that urban (1). Rural communities often have a higher proportion residents who lack health insurance, with comorbidities or disabilities, are aged ≥65 years, and limited access to care facilities intensive capabilities, which places these at increased risk for...
Cancer is a leading cause of disease burden globally, with more than 19·3 million cases and 10 deaths recorded in 2020. Research crucial to understanding the determinants cancer effects interventions, improving outcomes. We aimed analyse global patterns public philanthropic investment research.In this content analysis, we searched UberResearch Dimensions database UK data for human research funding awards from funders between Jan 1, 2016, Dec 31, Included award types were project programme...
Abstract Dengue is the most prevalent mosquito-borne viral disease in humans, and cases are continuing to rise globally. In particular, islands Caribbean have experienced more frequent outbreaks, all four dengue virus (DENV) serotypes been reported region, leading hyperendemicity increased rates of severe disease. However, there significant variability regarding surveillance reporting between islands, making it difficult obtain an accurate understanding epidemiological patterns Caribbean. To...
We describe recent results of the Advanced Research Projects Agency (ARPA) sponsored Consortium on Wideband All-Optical Networks which is developing architectures, technology components, and applications for ultrafast 100 Gb/s time-division multiplexing (TDM) optical networks. The shared-media networks we envision are appropriate providing low-access-delay bandwidth demand to both future high-burst rate (100 Gb/s) users as well aggregates lower-rate (i.e., a heterogeneous user population)....
Objective. To test the effectiveness of a Bayesian model employing subjective probability estimates for predicting success and failure health care improvement projects. Data Sources. Experts' assessment data development independent retrospective on 221 healthcare projects in United States, Canada, Netherlands collected between 1996 2000 validation. Methods. A panel theoretical practical experts literature organizational change were used to identify factors outcome efforts. was developed...
Zika virus is a flavivirus transmitted primarily by Aedes aegypti and albopictus mosquitoes, infection can be asymptomatic or result in an acute febrile illness with rash (1). during pregnancy cause of microcephaly other severe birth defects (2). Infection has also been associated Guillain-Barré syndrome (GBS) (3) thrombocytopenia (4,5). In December 2015, the Puerto Rico Department Health (PRDH) reported first locally acquired case infection. This report provides update to epidemiology...
Dengue is a vectorborne infectious disease caused by dengue viruses (DENVs), which are predominantly transmitted Aedes aegypti and albopictus mosquitos. four closely related (DENV-1-4), person can be infected with each serotype for total of infections during their lifetime. Areas where endemic in the United States its territories freely associated states include Puerto Rico, American Samoa, U.S. Virgin Islands, Federated Micronesia, Republic Marshall Palau. This report summarizes...
Dengue is one of the most common vectorborne flaviviral infections globally, with frequent outbreaks in tropical regions. In 2019 and 2020, Pan American Health Organization reported approximately 5.5 million dengue cases from Americas, highest number on record. United States, local virus (DENV) transmission has been all U.S. territories, which are characterized by climates that highly suitable for Aedes species mosquitoes, vector transmits dengue. endemic territories Samoa, Puerto Rico,...
Abstract During May 2022–April 2023, dengue virus serogroup 3 was identified among 601 travel-associated and 61 locally acquired cases in Florida, USA. All 203 sequenced genomes belonged to the same genotype III lineage revealed potential transmission chains which most occurred shortly after introduction, with little sustained transmission.
Distinguishing between non-severe and severe dengue is crucial for timely intervention reducing morbidity mortality. World Health Organization (WHO)-recommended warning signs offer a practical approach clinicians but have limited sensitivity specificity. This study aims to evaluate machine learning (ML) model performance compared WHO-recommended in predicting among laboratory-confirmed cases Puerto Rico. We analyzed data from Rico's Sentinel Enhanced Dengue Surveillance System (May...
Rocky Mountain spotted fever (RMSF) transmitted by the brown dog tick (Rhipicephalus sanguineus sensu lato) has emerged as a significant public health risk on American Indian reservations in eastern Arizona. During 2003–2012, more than 250 RMSF cases and 19 deaths were documented among Arizona's population. The high case fatality rate makes community-level interventions aimed at rapid sustained reduction of ticks urgent. Beginning 2012, two year pilot integrated prevention campaign called...
Zika virus is a flavivirus transmitted primarily by Aedes species mosquitoes; symptoms of infection include rash, arthralgia, fever, and conjunctivitis.*,† during pregnancy can cause microcephaly other serious brain anomalies (1), in rare cases, has been associated with Guillain-Barré syndrome (2) severe thrombocytopenia (3). This report describes the incidence reported symptomatic disease U.S. territory Puerto Rico age sex. During November 1, 2015-October 20, 2016, 62,500 suspected cases...
Dengue, the leading cause of arboviral disease worldwide, can be fatal without appropriate treatment.Among 7,528 confirmed or probable travel-associated U.S. dengue cases reported during 2010-2021, one in five (1,474, 20%) was 2019.This is 168% higher than annual average number 2010-2018 and 2020-2021 (approximately 550 per year) 61% 913 2016, second highest year on record.The as a fraction air traffic volume to international destinations outside North America Europe also 2019, with 41.9...
Problem/Condition: Dengue is the most prevalent mosquitoborne viral illness worldwide and endemic in Puerto Rico.Dengue's clinical spectrum can range from mild, undifferentiated febrile to hemorrhagic manifestations, shock, multiorgan failure, death severe cases.The disease presentation nonspecific; therefore, various other illnesses (e.g., arboviral respiratory pathogens) cause similar symptoms.Enhanced surveillance necessary determine prevalence, characterize epidemiology of disease,...
Long-standing systemic social, economic, and environmental inequities in the United States have put many communities of color (racial ethnic minority groups) at increased risk for exposure to infection with SARS-CoV-2, virus that causes COVID-19, as well more severe COVID-19-related outcomes (1-3). Because race ethnicity are missing a proportion reported COVID-19 cases, counties substantial information often excluded from analyses disparities (4). Thus, complement these case-based analyses,...
Leptospirosis, an acute bacterial zoonotic disease, is endemic in Puerto Rico. Infection approximately 10%-15% of patients with clinical disease progresses to severe, potentially fatal illness. Increased incidence has been associated flooding areas around the world. In 2022, Hurricane Fiona, a Category 1 hurricane, made landfall and inundated Rico heavy rainfall severe flooding, increasing risk for leptospirosis outbreak. response, Department Health (PRDH) changed guidelines make cases...
During July to November 2012, two botulism outbreaks (12 cases total) occurred in one all-male prison; both were associated with illicitly brewed alcohol (pruno) consumption. Inmate surveys conducted evaluate and develop prevention education strategies. Qualitative open-ended questions performed among inmates from rooms where learn about pruno Quantitative assessed knowledge gained after the preferred information sources. For quantitative surveys, 250 randomly selected by bed across...