Shafiq-Ur-Rehman Naseem

ORCID: 0000-0002-7676-5670
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About
Contact & Profiles
Research Areas
  • Immunodeficiency and Autoimmune Disorders
  • Food Allergy and Anaphylaxis Research
  • Cystic Fibrosis Research Advances
  • Allergic Rhinitis and Sensitization
  • Contact Dermatitis and Allergies
  • Respiratory and Cough-Related Research
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Vestibular and auditory disorders
  • Diabetes and associated disorders
  • Ion Channels and Receptors
  • Immune Response and Inflammation
  • Cerebral Venous Sinus Thrombosis
  • Acute Lymphoblastic Leukemia research
  • Food Safety and Hygiene
  • Blood disorders and treatments
  • Cardiovascular Syncope and Autonomic Disorders
  • Epigenetics and DNA Methylation
  • Ion channel regulation and function
  • Immune Cell Function and Interaction

Sultan Qaboos University Hospital
2016-2022

Institute of Child Health
2019

Sultan Qaboos University
2016

University of Pecs
2013

The coat protein I (COPI) complex mediates retrograde trafficking from the Golgi to endoplasmic reticulum (ER). Five siblings with persistent bacterial and viral infections defective humoral cellular immunity had a homozygous p.K652E mutation in γ1 subunit of COPI (γ1-COP). disrupts binding KDEL receptor impairs retrieval KDEL-bearing chaperones ER. Homozygous Copg1K652E mice increased ER stress activated T B cells, poor antibody responses, normal numbers cells that proliferated normally,...

10.1172/jci140494 article EN Journal of Clinical Investigation 2021-02-01

This study aimed to evaluate the relationship between food allergen sensitisation patterns and allergic manifestations in Omani patients highlight importance of specific immunoglobulin E (IgE) testing.This retrospective included all referred due Sultan Qaboos University Hospital (SQUH), Muscat, Oman, from November 2012 2016. Specific IgE blood testing was performed determine common foods known cause reactions.A total 164 were SQUH over period, with 35.4% presenting one manifestation, 48.8%...

10.18295/squmj.2018.18.04.009 article EN cc-by Sultan Qaboos University medical journal 2019-03-28

Anaphylaxis is an acute and potentially fatal allergic reaction. No studies have yet been conducted to evaluate the spectrum of anaphylactic reactions among Omani patients. As such, this study aimed describe clinical features, causes, investigation, management anaphylaxis patients presenting a tertiary care center in Oman.This retrospective took place between August 2005 June 2020 at allergy immunology clinic Sultan Qaboos University Hospital, Muscat, Oman. All diagnosed with during period...

10.5001/omj.2021.113 article EN cc-by-nc Oman Medical Journal 2021-10-18
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