A5083745721- High-pressure geophysics and materials
- Geological and Geochemical Analysis
- Water Treatment and Disinfection
- Heavy Metal Exposure and Toxicity
- Toxic Organic Pollutants Impact
- Lipid Membrane Structure and Behavior
- Heavy metals in environment
- Occupational and environmental lung diseases
- Per- and polyfluoroalkyl substances research
- X-ray Spectroscopy and Fluorescence Analysis
- X-ray Diffraction in Crystallography
- Fecal contamination and water quality
- Environmental Justice and Health Disparities
- Crystal Structures and Properties
- Wastewater Treatment and Reuse
- Protein Interaction Studies and Fluorescence Analysis
- Ion channel regulation and function
- Trace Elements in Health
- Air Quality and Health Impacts
- Protein Structure and Dynamics
- Radiation Dose and Imaging
- Effects and risks of endocrine disrupting chemicals
- Aluminum toxicity and tolerance in plants and animals
- Arsenic contamination and mitigation
- ATP Synthase and ATPases Research
TU Dortmund University
2015-2024
National Institute of Environmental Health Sciences
2013-2023
Colorado School of Mines
2020-2021
National Institutes of Health
2015-2021
Entertainment Industries Council
2018
Indiana Geological and Water Survey
2018
United States Geological Survey
2018
Ohio-Kentucky-Indiana Water Science Center
2018
University of Illinois System
2018
Delta Electronics (China)
2015-2018
In this article we summarize the results of a series studies that measured relative bioavailability (RBA) lead in variety soil and soil-like test materials. Reference material (Pb acetate) or Pb-contaminated soils were administered orally to juvenile swine twice day for 15 days. Blood samples collected from each animal at multiple times during course study, liver, kidney, bone sacrifice. All analyzed Pb. We estimated RBA by fitting mathematical models dose-response curves measurement end...
Mining, handling, processing, and personal or commercial use of asbestos-contaminated vermiculite have led to widespread contamination the Libby, Montana, area. We initiated a medical testing program in response reports respiratory illness community. The purpose this analysis was identify quantify asbestos-related radiographic abnormalities among persons exposed Libby examine associations between these outcomes participants' self-reported exposures. A cross-sectional interview were conducted...
Bioterrorist attacks involving letters and mail-handling systems in Washington, DC, resulted Bacillus anthracis (anthrax) spore contamination the Hart Senate Office Building other facilities US Capitol's vicinity.To provide information about nature extent of indoor secondary aerosolization B spores.Stationary personal air samples, surface dust, swab samples were collected under semiquiescent (minimal activities) then simulated active office conditions to estimate spores. Nominal size...
Safe drinking water at the point-of-use (tapwater, TW) is a United States public health priority. Multiple lines of evidence were used to evaluate potential human concerns 482 organics and 19 inorganics in TW from 13 (7 supply, 6 private well self-supply) home 12 (public supply) workplace locations 11 states. Only uranium (61.9 μg L–1, well) exceeded National Primary Drinking Water Regulation maximum contaminant level (MCL: 30 L–1). Lead was detected 23 samples (MCL goal: zero). Seventy-five...
SiO 2 is the main component of silicate melts and thus controls their network structure physical properties.The compressibility viscosities at depth are governed by short range atomic electronic structure.We measured O K-edge Si L 2,3 -edge in silica up to 110 GPa using X-ray Raman scattering spectroscopy, found a striking match calculated spectra based on structures from molecular dynamic simulations.Between 20 27 GPa, [4] species converted into mixture [5] [6] between 60 70 becomes...
Per- and polyfluoroalkyl substances (PFAS) are a group of highly fluorinated synthetic chemicals that were originally developed for uses as surfactants surface protectors. Increasingly, specific this class being found in environmental media (e.g., water, soils, sediments, food sources), concerns regarding exposure to humans receptors have been described by the public, legislators, general population. Data suggest some PFAS (such certain long-chain ones) bioaccumulate long biological...
Humans are primary drivers of environmental contamination worldwide, including in drinking-water resources. In the United States (US), federal and state agencies regulate monitor public-supply drinking water while private-supply monitoring is rare; current lack directly comparable information on contaminant-mixture exposures risks between private- public-supplies undermines tapwater (TW) consumer decision-making.We compared residential point-of-use TW at Cape Cod, Massachusetts, where both...
Most animal studies conducted to determine the bioavailability of lead have, in past, employed rodents or lagomorphs as experimental models. In this paper issues and data are presented which raise questions uncertainties about employing for investigations into lead. These include: (1) possible role coprophagy feeding behavior reducing estimates bioavailability; (2) anatomical physiological differences related may influence derived rats rabbits; (3) evidence relatively high biliary excretion...
A pilot-scale expanded target assessment of mixtures inorganic and organic contaminants in point-of-consumption drinking water (tapwater, TW) was conducted Puerto Rico (PR) to continue inform TW exposures corresponding estimations cumulative human-health risks across the US. In August 2018, a spatial synoptic pilot than 524 37 chemicals 14 locations (7 home; 7 commercial) PR. follow-up 3-day temporal variability December 2018 at two (1 home, 1 included daily pre- post-flush samples....
Abstract Iron-bearing carbonates are candidate phases for carbon storage in the deep Earth and may play an important role Earth’s cycle. To elucidate properties of at conditions Earth, we investigated pressure driven magnetic high spin to low transition synthetic siderite FeCO 3 magnesiosiderite (Mg 0.74 Fe 0.26 )CO single crystals pressures up 57 GPa using diamond anvil cells x-ray Raman scattering spectroscopy directly probe iron 3d electron configuration. An extremely sharp crystal occurs...
In the United States (US), private-supply tapwater (TW) is rarely monitored. This data gap undermines individual/community risk-management decision-making, leading to an increased probability of unrecognized contaminant exposures in rural and remote locations that rely on private wells. We assessed point-of-use (POU) TW three northern plains Tribal Nations, where ongoing arsenic (As) interventions include expansion small community water systems POU adsorptive-media treatment for Strong Heart...
Bottled water (BW) consumption in the United States and globally has increased amidst heightened concern about environmental contaminant exposures health risks drinking supplies, despite a paucity of directly comparable, environmentally-relevant exposure data for BW. This study provides insight into cumulative to human from inorganic/organic/microbial contaminants
X-ray emission spectra reveal that under pressure conditions of Earth's lower mantle, the compaction mechanism in amorphous germanium dioxide on atomic scale is similar to its crystalline form.
Mixtures of contaminants are observed in public-supply drinking water. Frequent exceedances human-health advisories indicate potential cumulative risk to vulnerable subpopulations and the continued need for broad chemical assessments tapwater.
X-ray Raman scattering (XRS) spectroscopy is an inelastic method that uses hard X-rays of the order 10 keV to measure energy-loss spectra at absorption edges light elements (Si, Mg, O etc.), with energy resolution below 1 eV. The high-energy employed this technique can penetrate thick or dense sample containers such as diamond anvils in high-pressure cells. Here, we describe use custom-made conical miniature less than 500 µm thickness which allow pressure generation up 70 GPa. This set-up...
A portable IR fiber laser-heating system, optimized for X-ray emission spectroscopy (XES) and nuclear inelastic scattering (NIS) with signal collection through the radial opening of diamond anvil cells near 90°with respect to incident beam, is presented. The system offers double-sided on-axis heating by a single laser source zero attenuation incoming X-rays other than high-pressure environment. description which has been tested pressures above 100 GPa temperatures up 3000 K, given. XES...
The high spin to low transition of siderite is studied by simultaneous X-ray emission and Raman scattering spectroscopy.
The past decade has seen tremendous expansion in the production and application of engineered nanomaterials (ENMs). unique properties that make ENMs useful marketplace also their interactions with biological systems difficult to anticipate critically important explore. Currently, little is known about health effects human exposure these materials.As part its role supporting National Nanotechnology Initiative, Institute Environmental Health Sciences (NIEHS) developed an integrated, strategic...
Abstract Much of Earth’s carbon may have been stripped away from the silicate mantle by dense metallic-iron during core formation. However, at deep magma ocean conditions becomes less siderophile and thus large amounts it be stranded instead in mantle. Here, we describe structure compaction mechanisms carbonate glass to pressures. Our results, based on non-resonant inelastic X-ray scattering, diffraction ab initio calculations, demonstrate a pressure-induced change hybridization sp 2 3...
Using a combination of high resolution X-ray powder diffraction and Raman scattering spectroscopy at the B K- Ca L<sub>2,3</sub>-edges, we analyzed reaction products Ca(BH<sub>4</sub>)<sub>2</sub>after annealing 350 °C 400 under vacuum conditions.