A5002382309- Systemic Sclerosis and Related Diseases
- Noise Effects and Management
- Mast cells and histamine
- Sarcoidosis and Beryllium Toxicity Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Systemic Lupus Erythematosus Research
- Asthma and respiratory diseases
- Connective Tissue Growth Factor Research
- Heavy Metal Exposure and Toxicity
- Dermatological and Skeletal Disorders
- Vitamin C and Antioxidants Research
- Eosinophilic Esophagitis
- Infectious Diseases and Tuberculosis
- HIV/AIDS drug development and treatment
- Synthesis and Characterization of Heterocyclic Compounds
- Vitamin D Research Studies
- Musculoskeletal synovial abnormalities and treatments
- Diet and metabolism studies
- Research on Leishmaniasis Studies
- Kruppel-like factors research
- Diagnosis and treatment of tuberculosis
- Inflammatory Myopathies and Dermatomyositis
- Heavy metals in environment
- Rheumatoid Arthritis Research and Therapies
- Allergic Rhinitis and Sensitization
University of Pennsylvania
2020-2024
Hospital of the University of Pennsylvania
2020
Johns Hopkins University
2015-2017
Johns Hopkins Medicine
2015-2016
National Postdoctoral Association
2014
Yale University
2012
Medical University of South Carolina
2011
National Center for Environmental Health
2011
National Center for Immunization and Respiratory Diseases
2011
Centers for Disease Control and Prevention
2009
Objective To estimate the incidence of serious infections in patients with HIV infection and autoimmune disease who were treated tumor necrosis factor (TNF) inhibitors, to compare these rates by stratified viral load levels. Methods Using a unified search strategy, 4 centers identified HIV‐infected exposed TNF inhibitors. Patient characteristics data assessed via chart review all ≥18 years old received inhibitor therapy after diagnosis, between January 1999 March 2015. Results We studied 23...
Background. The prevalence of elevated blood lead levels (EBLLs) has decreased nationally, creating challenges in identifying children at risk. Methods. In a community known to have hazards, we screened with field-administered capillary test and asked parents complete questionnaire about risk factors. Results. Of the 77 child-parent pairs parental questionnaire, 4 had finger stick ≥10 µg/dL. these, one child confirmatory venous level >10 µg/dL (1.3%; 95% CI = 0.0%-4.7%), which is near US...
Background: AVID200 is a novel, potent TGF-beta receptor ectodomain-based trap designed to selectively neutralize 1 and 3. These two isoforms have been implicated as central mediators of the pathogenesis systemic sclerosis (SSc). avoids inhibition 2, isoform that supports normal cardiac function hematopoiesis. Objectives: This first-in-human study (AVID200-01; NCT03831438 ) Phase 1, open label, multicenter, cohort dose-escalation trial evaluate safety, tolerability, pharmacokinetic (PK)...
Sarcoidosis is characterized by noncaseating granulomas that can affect multiple organs. Due to the lack of prospective studies regarding treatment hepatic sarcoidosis with ursodeoxycholic acid (UDCA), we set out evaluate its effects in a single-center, open-label, prospective, pre-post study.
Introduction Crystalline arthritis (CA), characterized by acute joint pain and erythema secondary to calcium pyrophosphate deposition (CPPD, or pseudogout) monosodium urate crystals (gout), is a potentially underreported complication following allogeneic hematopoietic cell transplant (alloHCT). Graft-versus-host disease prophylaxis with calcineurin inhibitors (CNIs) causes hypomagnesemia hyperuricemia, resulting in CA. CA related tacrolimus has yet be alloHCT. Case report We retrospectively...
A 52-year-old right-handed woman, with occupational exposure to heavy cleaning equipment and newspaper delivery, presented the Johns Hopkins Hospital emergency department in great distress. She had just exited subway. While riding train holding a pole for stability, she abruptly developed excruciating pain complete inability flex or extend her left elbow. Rheumatology consultation identified unilateral fullness of elbow, …
Rheumatoid vasculitis is a rare extra-articular complication of rheumatoid arthritis. The most common manifestation cutaneous; however, it can manifest in various organ systems and associated with high degree morbidity mortality. Diagnosis challenging, there are no validated diagnostic or classification criteria. Most cases should be confirmed tissue biopsy when possible given the severity disease extent immunosuppression required to treat this condition. We report case 54-year-old white...
INTRODUCTION: Granulomatous diseases within the gastrointestinal (GI) tract make up a limited list of conditions. Identification exact pathology, however, isn’t always trivial particularly with atypical presentations, often requiring multidisciplinary approach to arrive at diagnosis. CASE DESCRIPTION/METHODS: Here, we describe case 19-year-old man presented recurrent hematemesis and 30 lbs weight loss over 4 months. He had HR 114 BP 84/61 was thin-appearing without tender abdomen. Labs were...