Abstract Backgrounds Silver diamine fluoride (SDF) has clinical success in arresting dentin caries, this study aimed to investigate its mechanism of action. Methods Using a computer-controlled artificial mouth, we studied the effect 38% SDF on cariogenic biofilms and carious lesions. We used five common bacteria ( Streptococcus mutans, sobrinus, Lactobacillus acidophilus, rhamnosus Actinomyces naeslundii ) form biofilm that generated lesions with depth approximately 70 um human blocks....

This review aims to investigate the clinical effectiveness of silver diamine fluoride (SDF) in arresting dental caries among children. A systematic search publications was conducted with key words “silver fluoride,” diammine “diamine or “diammine fluoride” as well their translation Chinese, Japanese, Portuguese, and Spanish 7 databases: PubMed (English), Embase Scopus China National Knowledge Infrastructure (Chinese), Ichushi-web (Japanese), Biblioteca Virtual em Saude (Portuguese), en Salud...

International Journal of Paediatric Dentistry 2011; 22: 2–10 Background. Silver diamine fluoride (SDF) has been shown to be a successful treatment for arresting caries. However, the mechanism SDF is elucidated. Aim. To characterize effects on dentine carious induced by Streptococcus mutans and Actinomyces naeslundii. Design. Thirty‐two artificially demineralized human blocks were inoculated: 16 with S. A. naeslundii . Either or water was applied eight in each group. Biofilm morphology,...

This ex vivo study compared the physico-chemical structural differences between primary carious teeth biannually treated with silver diamine fluoride (SDF) and without such treatment.Twelve upper-central incisors were collected from 6-year-old children. Six had arrested caries after 24-month biannual SDF applications 6 active when there was no topical treatment. The mineral density, elemental contents, surface morphology, crystal characteristics assessed by micro-computed tomography...

This in vitro study investigated the effects of silver diamine fluoride (SDF) on dentine carious lesion with cariogenic biofilm.Thirty human blocks were inoculated Streptococcus mutans and Lactobacillus acidophilus dual-species biofilm to create lesion. They equally divided into test control group receive topical application SDF water. After incubation anaerobically using micro-well plate at 37oC for 7 days, biofilms evaluated kinetics, morphology viability by colony forming units (CFU),...

Silver diamine fluoride (SDF) is found to promote remineralization and harden the carious lesion. Hydroxyapatite crystallization a crucial process in remineralization; however, role of SDF crystal formation unknown. We designed an vitro experiment with calcium phosphate different concentrations (0.38, 1.52, 2.66, 3.80 mg/mL) investigate effect this additive on nucleation growth apatite crystals. Two control groups were also prepared-calcium (CaCl

This study investigated the effect of silver diamine fluoride (SDF) and potassium iodide (KI) treatment on secondary caries prevention tooth discolouration in glass ionomer cement (GIC) restoration. Cervical GIC restorations were done 30 premolars with: Group 1, SDF + KI; 2, (positive control); 3, no (negative control). After cariogenic biofilm challenge, demineralisation dentine adjacent to restoration was evaluated using micro-computed tomography (micro-CT) Fourier transform infrared...

Objective To determine the short‐term stability of free fluoride ion concentrations and acidity (p H values) three commercially available SDF solutions over time. Methods Three products for caries control were studied: C ariestop‐12%, ariestop‐30% S aforide‐38%. Their expected 14,200, 35,400 44,800 ppm, respectively. The determined with an ion‐selective electrode. was a p measurements performed when open at 7 28 days. Results mean freshly opened bottles 12,525 ± 450, 13,200 2060 55,800 2536...

The expression of cysteine cathepsins in human carious dentine suggests that this enzyme contributes to the collagen degradation caries progress. This study investigated whether silver diamine fluoride (SDF) inhibited activity cathepsins.Three commercial SDF solutions with concentrations at 38%, 30% and 12% were studied. Two same ion (F(-)) as 38% solutions, 2 (Ag(+)) prepared. Five samples each experimental solution used their inhibitory effect on two (B K) using cathepsin assay kits....

Laboratory studies have demonstrated that enamel-like mineralized tissue can be regenerated and used to repair enamel loss. This has implications for the management of noncarious tooth loss resulting from dental erosion, attrition, abrasion. In this study, we designed a hydrogel biomimetic mineralization model regeneration with prismatic structure. The tissue, which was generated by on an etched surface in presence 500 ppm fluoride, analyzed scanning electron microscopy, X-ray diffraction,...