James C. Lin

ORCID: 0000-0002-7848-9841
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About
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Research Areas
  • Electromagnetic Fields and Biological Effects
  • Wireless Body Area Networks
  • Ultrasound and Hyperthermia Applications
  • Noise Effects and Management
  • Energy Harvesting in Wireless Networks
  • Microwave Imaging and Scattering Analysis
  • Biofield Effects and Biophysics
  • Photoacoustic and Ultrasonic Imaging
  • Molecular Communication and Nanonetworks
  • Non-Invasive Vital Sign Monitoring
  • Ultrasonics and Acoustic Wave Propagation
  • Cardiac Arrhythmias and Treatments
  • Biomedical and Engineering Education
  • Electromagnetic Compatibility and Measurements
  • Ultrasound Imaging and Elastography
  • Cardiac electrophysiology and arrhythmias
  • Wireless Power Transfer Systems
  • Advanced MRI Techniques and Applications
  • Melanoma and MAPK Pathways
  • Microwave and Dielectric Measurement Techniques
  • Monoclonal and Polyclonal Antibodies Research
  • Microbial Inactivation Methods
  • Child Development and Digital Technology
  • Infrared Thermography in Medicine
  • Health, Environment, Cognitive Aging

University of Illinois Chicago
2016-2025

Siliconware Precision Industries (Taiwan)
2021-2024

Taipei Medical University
2022-2024

Shanghai Jiao Tong University
2022-2024

Massachusetts Institute of Technology
2024

Bristol-Myers Squibb (United States)
2002-2023

University of Michigan–Ann Arbor
2023

Ross School
2023

Universidad de Cantabria
2023

University of Chicago
2014-2022

A microwave technique for measuring respiratory movements of man and animal is described. The noncontacting based on the scattering continuous wave radiation. Preliminary results are shown both man, indicating usefulness procedure.

10.1109/proc.1975.9992 article EN Proceedings of the IEEE 1975-01-01

2-Aminothiazole (1) was discovered as a novel Src family kinase inhibitor template through screening of our internal compound collection. Optimization successive structure−activity relationship iterations identified analogs 2 (Dasatinib, BMS-354825) and 12m pan-Src inhibitors with nanomolar to subnanomolar potencies in biochemical cellular assays. Molecular modeling used construct putative binding model for Lck inhibition by this class compounds. The framework key hydrogen-bond interactions...

10.1021/jm060727j article EN Journal of Medicinal Chemistry 2006-10-24

A microwave technique for recording apexcardiograms is reported. The based on detecting changes in the reflected microwaves caused by movement of chest wall response to left-ventricle activity. Results show that useful delineating fine structures precordial movement.

10.1109/tmtt.1979.1129682 article EN IEEE Transactions on Microwave Theory and Techniques 1979-06-01

The cataractogenic effects of near-zone 2450-MHz radiation in rabbits are presented. power deposition pattern inside the eyes and head has been determined using a thermocouple technique. It was found that peak absorption 0.92 W/kg occurred between lens eye retina for each milliwatt/square centimeter incident. Time power-density studies indicated threshold 150-mW/cm2 incident, or 138-W/kg behind 100 min. time decreased with increasing density. Agreement vivo intraocular temperature...

10.1109/tmtt.1975.1128606 article EN IEEE Transactions on Microwave Theory and Techniques 1975-06-01

* ICNIRP, c/o BfS—G. Ziegelberger, Ingolstaedter Landstr. 1, 85764 Oberschleissheim, Germany. For correspondence contact G. Ziegelberger at the above address, or email [email protected]. (Manuscript accepted 3 February 2010)

10.1097/hp.0b013e3181d85908 article EN Health Physics 2010-07-01

Because blood loss attributable to laboratory testing is the primary cause of anemia among preterm infants during first weeks life, we quantified lost phlebotomy overdraw, ie, excess that might be avoided. We hypothesized overdraw in requested by hospital was a common occurrence, clinical factors associated with excessive would identified, and some these are potentially correctable. DESIGN, OUTCOME MEASURES, AND ANALYSIS: Blood samples drawn for purposes from neonates cared our 2 neonatal...

10.1542/peds.106.2.e19 article EN PEDIATRICS 2000-08-01

The IEEE Standards Association recently formally approved a new C95.1 "Standard for Safety Levels with Respect to Human Exposure Radio Frequency Electromagnetic Fields, 3 kHz 300 GHz." Official publication of the standard by was expected late 2005, or soon thereafter. contains some features current ICNIRP guidelines, but it also includes number differences. is not identical even frequencies used in cellular mobile communications and wireless devices systems. Moreover, newly departs major...

10.1109/map.2006.1645601 article EN IEEE Antennas and Propagation Magazine 2006-02-01

Abstract Purpose To present and discuss numerical calculations of the specific absorption rate (SAR) temperature in comparison to regulatory limits. While it is possible monitor whole‐body or whole‐head average SAR and/or core body during MRI practice, this not generally true for local values temperatures throughout body. methods calculation are constantly being refined, interpreting results these light limits also warrant discussion. Materials Methods Numerical human head a volume coil at...

10.1002/jmri.20977 article EN Journal of Magnetic Resonance Imaging 2007-07-25

The induced fields and the associated power deposition in mail exposed to HF electromagnetic (EM) have been investigated theoretically using spherical models. electric inside model either plane wave or near can be described adequately by a combination of quasi-static magnetic induction solutions. It is shown that for field impedances less than 1200/spl pi//spl Omega/ magnetically energy absorption predominates. Therefore, H must measured obtain any estimate hazards due exposure. For 70-kg...

10.1109/tmtt.1973.1128133 article EN IEEE Transactions on Microwave Theory and Techniques 1973-12-01

A search for structurally diversified Tyk2 JH2 ligands from 6 (BMS-986165), a pyridazine carboxamide-derived ligand as clinical inhibitor currently in late development the treatment of psoriasis, began with survey six-membered heteroaryl groups place N-methyl triazolyl moiety 6. The X-ray co-crystal structure an early lead (12) revealed potential new binding pocket. Exploration pocket resulted two frontrunners candidate. hydrogen bonding interaction Thr599 was achieved tertiary amide moiety,...

10.1021/acs.jmedchem.0c01698 article EN Journal of Medicinal Chemistry 2020-12-28

Nonreceptor protein tyrosine kinases including Lck, ZAP-70, and Itk play essential roles in T-cell receptor (TCR) signaling. Gene knockout studies have revealed that mice lacking these individual exhibit various degrees of immunodeficiency; however, highly selective small molecule inhibitors as potential immunosuppressive agents not been identified. Here we discovered two novel compounds, BMS-488516 BMS-509744, potently selectively inhibit kinase activity. The compounds reduce TCR-induced...

10.1021/bi049428r article EN Biochemistry 2004-08-01

This paper presents a new microwave antenna design with improved heating at the tip for interstitial hyperthermia and thermocoagulation. Temperature distribution patterns surrounding conventional insulated sleeved coaxial slot radiator are measured in saline phantom under transient steady-state conditions. The provides an temperature over active region of radiator. In contrast to cold zone maximal (sixfold greater) power deposition its tip.

10.3109/02656738709140371 article EN International Journal of Hyperthermia 1987-01-01

We have studied the interaction of microwaves with blood-brain barrier in Wistar rats. Indwelling catheters were placed femoral vein. Evans blue isotonic saline was used as a visual indicator permeation. Irradiation pulsed 2450-MHz for 20 min at average power densities 0.5 to 2600 mW/cm/sup 2/, which resulted specific absorption rages (SARs) 0.04 200 mW/g brain, did not produce staining, except regions that normally are highly permeable. When incident density increased 3000 2/ (SAR 240...

10.2307/3575686 article EN Radiation Research 1982-01-01

When a human subject is exposed to pulsed microwave radiation, an audible sound occurs which appears originate from within or immediately behind the head. Laboratory studies have also indicated that evoked auditory activities may be recorded cats, chinchillas, and guinea pigs. Using spherical model of head, this paper analyzes process by energy cause observed effect. The problem formulated in terms thermoelasticity theory absorbed represents volume heat source depends on both space time....

10.1109/tmtt.1977.1129167 article EN IEEE Transactions on Microwave Theory and Techniques 1977-07-01

Recent interest and current optimism regarding battery-charging wireless power-transfer technology are driven by the ubiquity of cell phones other mobile communication devices. In some ways, this is to make a dream come true: truly or portable device, completely free from being tethered in any way. The concept power transfer not new, even for charging batteries. Cellular service users customers may be annoyed do want bothered with having plug device into an electrical outlet. If true - as...

10.1109/map.2013.6529362 article EN IEEE Antennas and Propagation Magazine 2013-04-01
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