A5019787552- Photoreceptor and optogenetics research
- Protist diversity and phylogeny
- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Molecular Communication and Nanonetworks
- Molecular Biology Techniques and Applications
- Bacterial biofilms and quorum sensing
- Wastewater Treatment and Nitrogen Removal
- Oral microbiology and periodontitis research
- Photosynthetic Processes and Mechanisms
- Genomics and Rare Diseases
- Genomic variations and chromosomal abnormalities
- Neuroscience and Neuropharmacology Research
- bioluminescence and chemiluminescence research
- Cancer Genomics and Diagnostics
The University of Tokyo
2014-2024
Japan Agency for Marine-Earth Science and Technology
2021
Sphere Institute
2018
Saitama Children's Medical Center
2017
Marine Ecology Research Institute
2017
Light-activated, ion-pumping rhodopsins are broadly distributed among many different bacteria and archaea inhabiting the photic zone of aquatic environments. Bacterial proton- or sodium-translocating can convert light energy into a chemiosmotic force that be converted cellular biochemical energy, thus represent widespread alternative form photoheterotrophy. Here we report genome marine flavobacterium Nonlabens marinus S1-08(T) encodes three types rhodopsins: rhodopsin 1 (NM-R1), 2 (NM-R2), 3...
Epilepsies are common neurological disorders and genetic factors contribute to their pathogenesis. Copy number variations (CNVs) increasingly recognized as an important etiology of many human diseases including epilepsy. Whole‐exome sequencing (WES) is becoming a standard tool for detecting pathogenic mutations has recently been applied CNVs. Here, we analyzed 294 families with epilepsy using WES, focused on 168 no causative single nucleotide variants in known epilepsy‐associated genes...
Proteorhodopsin (PR) is a light-driven proton pump that found in diverse bacteria and archaea species, widespread marine microbial ecosystems. To date, many studies have suggested the advantage of PR for microorganisms sunlit environments. The ecophysiological significance still not fully understood however, including drivers gene gain, retention, loss different species. explore this question we sequenced 21 Flavobacteriia genomes polyphyletic origin, which encompassed both PR-possessing as...
Light-driven ion-pumping rhodopsins are widely distributed among bacteria, archaea, and eukaryotes in the euphotic zone of aquatic environment. H+-pumping rhodopsin (proteorhodopsin: PR), Na+-pumping (NaR), Cl--pumping (ClR) have been found marine which suggests that these genes evolved independently ocean. Putative microbial were identified genome sequences Cytophagia. In present study, one was heterologously expressed Escherichia coli cells protein named Rubricoccus marinus halorhodopsin...
Pseudomonas aeruginosa is one of the most common model bacterial species, and genomes hundreds strains this species have been sequenced to date. However, currently there only available genome an oceanic isolate. Here, we report two complete six draft sequences P. isolates from open ocean.
ABSTRACT Here, we report the draft genome sequence of Rubricoccus marinus SG-29 T , a bacterium isolated from western North Pacific Ocean. R. possesses two different types rhodopsin genes and belongs to family Rhodothermaceae with which halophilic, thermophilic, marine bacteria are associated.
The ammonia monooxygenase subunit A (amoA) gene has been used to investigate the phylogenetic diversity, spatial distribution and activity of ammonia-oxidising archaeal (AOA) bacterial (AOB), which contribute significantly nitrogen cycle in various ecosystems. Amplicon sequencing amoA is a widely method; however, it produces inaccurate results owing lack 'universal' primer set. Moreover, currently available sets suffer from amplification biases, can lead severe misinterpretation. Although...
Winogradskyella sp. strain PG-2 is a marine flavobacterium isolated from surface seawater. This organism contains proteorhodopsin, which can convert light energy into available forms of biochemical energy. Here, we present its complete genome sequence and annotation, provide further insights the life strategy proteorhodopsin-mediated phototrophy in ocean.
Abstract The ammonia monooxygenase subunit A ( amoA ) gene has been used to investigate the phylogenetic diversity, spatial distribution, and activity of ammonia-oxidizing archaeal (AOA) bacterial (AOB), which contribute significantly nitrogen cycle in various ecosystems. Amplicon sequencing is a widely method; however, it produces inaccurate results owing lack ‘universal’ primer set. Moreover, currently available sets suffer from amplification biases, can lead severe misinterpretation....