A5066334063- Advanced X-ray Imaging Techniques
- Advanced X-ray and CT Imaging
- X-ray Spectroscopy and Fluorescence Analysis
- Medical Imaging Techniques and Applications
- Orthopedic Surgery and Rehabilitation
- Bone Tumor Diagnosis and Treatments
- Infrared Thermography in Medicine
- Orthopaedic implants and arthroplasty
- Astrophysical Phenomena and Observations
- Nuclear Physics and Applications
- Musculoskeletal synovial abnormalities and treatments
- Radiation Dose and Imaging
- Molecular Biology Techniques and Applications
- Laser-Plasma Interactions and Diagnostics
- Digital Radiography and Breast Imaging
Inserm
2020-2022
Synchrotron Radiation for Biomedicine
2020-2022
École de Technologie Supérieure
2021
Université Grenoble Alpes
2018-2020
TechnipFMC (France)
2019
Monash University
2018
Centre Hospitalier Universitaire de Grenoble
2018
Laboratoire de Physique du Rayonnement et de la Lumière
2018
We develop a speckle-tracking method for x-ray phase-contrast imaging, based on the concept of geometric flow. This flow is conserved current associated with deformation illuminating speckles induced by passage through sample. The provides rapid, efficient, and accurate algorithm quantitative phase imaging. It highly photon efficient able to image dynamic objects, since single radiograph sample sufficient recovery. experimentally quantify resolution contrast approach both two-dimensional...
We develop X-ray Multi-modal Intrinsic-Speckle-Tracking (MIST), a form of speckle-tracking that is able to recover both the position-dependent phase shift and small-angle scattering (SAXS) signal object. MIST based on combining Fokker-Planck description paraxial optics, with an optical-flow formalism for speckle-tracking. Only two images need be taken in presence sample, corresponding different transverse positions speckle-generating membrane, order refractive local-SAXS properties sample....
We develop a means for speckle-based phase imaging of the projected thickness single-material object, under assumption illumination by spatially random time-independent x-ray speckles. These speckles are generated passing x rays through suitable mask. The method makes use single image obtained in presence which serves to deform illuminating speckle field relative reference (which only needs be measured once) mask and absence object. implicitly rather than explicitly tracks speckles, utilizes...
Since the invention of Computed Tomography (CT), many technological advances emerged to improve image sensitivity and resolution. However, no new source types were developed for clinical use. In this study, first time, coherent monochromatic X-rays from a synchrotron radiation used acquire 3D CTs on patients. The aim work was evaluate potential images acquired using Synchrotron Radiation CT (SRCT). SRCTs tuned at 80 keV (0.350 × 0.350 2 mm
X-ray phase contrast imaging (PCI) has shown great potential for clinical investigation of soft tissues. However, most the existing PCI modalities require either a partially coherent source such as synchrotron or complex setups that are barely compatible with low-dose and patient tomography. This work demonstrates possibility to efficiently achieve on low coherence system conventional tube detector routine. was accomplished by adapting speckle-based setup numerical retrieval processing...
Abstract X-ray Phase Contrast Imaging (PCI) is an emerging modality whose availability in clinics for mammography and lung imaging expected to materialize within the coming years. In this study, we evaluate PCI Computed Tomography (PCI-CT) performances with respect current conventional modalities context of osteo-articular disorders diagnosis. PCI-CT was performed on 3 cadaveric human hands wrists using a synchrotron beam. Conventional CT, MRI Ultrasound were also these three samples routine...
X-ray Phase Contrast Imaging (PCI) is an emerging modality that will be in the next few years available a wider range of preclinical set-ups. In this study, we compare imaging technique with conventional modalities osteoarthritis mouse model. contrast was performed on 6 post-mortem, monoiodoacetate-induced knees and control knees. The mice were then imaged using magnetic resonance micro computed tomography. Examples surrogate markers are reported: local distances within articular space,...
X-ray phase contrast imaging can provide improved or complementary information to traditional attenuation-based imaging, making the field a vast and rapidly evolving research subject. speckle-based (SBI) is one phase-contrast approach that has shown significant potential in providing both high sensitivity resolution while using very simple experimental setup. With aim of transferring such phase-contrast-based techniques from synchrotron laboratory sources, issue deposited radiation dose...
Standard histopathological examination is the gold standard for many disease diagnoses although technique limited with no full 3D volume analysis possible. Three dimensional X-ray Phase-Contrast Imaging(PCI) methods have been under constant and fast developments in recent decades due to their superior performance imaging low density objects ability provide complementary information compared attenuation based imaging. Despite progresses, Phase Contrast Tomography still encounters remaining...
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Objectives: X-ray Phase Contrast Imaging (PCI) is an emerging modality whose availability in clinics for mammography and lung imaging expected to materialize within the coming years. In this study, we evaluate PCI performances with respect current conventional modalities context of osteo-articular disorders diagnosis.Materials Methods: was performed on 3 cadaveric human hands wrists using a synchrotron beam. Conventional CT, MRI Ultrasound were also these three samples routine procedures as...
Understanding the mechanisms that underpin post-natal maturation of articular cartilage is crucial importance for designing next generation tissue engineering strategies and potentially repairing diseased or damaged cartilage. In general, postnatal cartilage, which a wholesale change in collagen structure function to accommodate growth organism, occurs over timescale ranging from months years. Conversely dissolution structural organization also long timescales hallmark degeneration. Our...
Understanding the mechanisms that underpin post-natal maturation of articular cartilage is crucial importance for designing next generation tissue engineering strategies and potentially repairing diseased or damaged cartilage. In general, postnatal cartilage, which a wholesale change in collagen structure function to accommodate growth organism, occurs over timescale ranging from months years. Conversely dissolution structural organization also long timescales hallmark degeneration. Our...